219 zoekresultaten voor “population” in de Publieke website
-
Shaping Massive Galaxies: the structural evolution of galaxies across
Galaxies in the local Universe fall into two main categories of spirals and ellipticals. In this Thesis, we explore the structural evolution of galaxies into this bimodal distribution.
-
Resolving a bioindicator diatom species complex using genomic approaches for freshwater biomonitoring
This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;
-
Pharmacogenomics in Drug Development: Implementation and Application of PKPD Model Based Approaches
Model based approaches, integrating physiological parameters or linking exposure with response, are powerful tools to quantify and evaluate the impact of genetic differences that are reflected as variability of drug exposure and/or clinical response(s). This thesis “Pharmacogenomics in Drug Development: …
-
Benchmarking Discrete Optimization Heuristics
This thesis involves three topics: benchmarking discrete optimization algorithms, empirical analyses of evolutionary computation, and automatic algorithm configuration.
-
Towards predictive cardiovascular safety: a systems pharmacology approach
Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski
-
Online Course The Great Sustainability Transition
In this course, you will learn about sustainability and staying with the environmental boundaries of our planet. You will gain an understanding of the effects of growing affluence and population growth, the key challenges we are facing, and ways to influence your direct environment.
-
Piecewise deterministic Markov processes: an analytic approach
Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans
-
Developing metabolomics for a systems biology approach to understand Parkinson's disease
Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…
-
Monsters in the Deep: Using simulations to understand the excess baryonic mass in the centres of high-mass, early-type galaxies
This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…
-
Impact en stad
De Universiteit Leiden en de stad Den Haag werken nauw samen om de impact van ons onderzoek en onderwijs te vergroten en zo maximaal bij te dragen aan de ontwikkeling van de stad.
-
The assembly history of the milky way nuclear star cluster
Promotor: P. T. de Zeeuw, Co-promotor: N. Neumayer; G. van de Ven
-
Human-wildlife Interactions in the Western Terai of Nepal
Large carnivores and humans, along with their livestock, have co-existed for thousands of years. However, human population growth and an increase in economic activities are modifying the landscape for large carnivores and their prey.
-
Sound Investigation: Effects of noise on marine animals across trophic levels
Anthropogenic noise has been shown to affect marine animals in various ways, this may have fitness consequences at individual and population level. This thesis aims to increase insight into the quantification of sound-induced behavioural responses that are relevant to fitness, and into factors that…
-
On the Emergence of the Energy Transition
The energy system is at the heart of two of the greatest challenges of the 21st century: decreasing CO2 emissions to meet the ambitions of the Paris agreement while fulfilling the growing energy demand associated with the economic aspirations of a growing world population.
-
The spin evolution of accreting and radio pulsars in binary systems
Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.
-
Inkomen en afkomst zijn risicofactoren bij kans op hart- en vaatziekten
Nederlanders met lage inkomens lopen tot 1,5 keer meer risico op het krijgen van een hartaanval of beroerte dan rijkere landgenoten. Bij Surinaamse Hindoestanen is dit risico 1,9 keer hoger. Dat blijkt uit onderzoek van het LUMC en het HagaZiekenhuis. Nederlandse artsen kijken tot nu toe niet naar deze…
-
Health Perspectives. Results from population-based studies of the Dutch and the Indonesian populations
Promotie
-
Onderwijs
In het Leids Universitair Medisch Centrum (LUMC) word je klaargestoomd voor de wereld van morgen. We brengen op een unieke manier onderzoek en patiëntenzorg samen in ons onderwijs.
- Agenda master
-
Ecology of the Ethiopian wolf in a changing landscape: Human carnivore interactions in Afroalpine ecosystems of Ethiopia
Do Ethiopian wolves change their diet and foraging strategy in the landscape under different land uses? How land use affect Afro-alpine rodent Communities? How important are Afro-alpine natural resources utilisation for local livelihoods? What is the human perception of conflict in the Afro-alpine a…
-
Van het acute zorgdoolhof naar een acuut zorgnetwerk
Acute zorginstanties in Nederland zijn overbelast en dat zorgt voor grote problemen. Arts-onderzoeker Naomi Minderhout deed daarom de afgelopen jaren aan de Health Campus in Den Haag onderzoek naar hoe de acute zorg in Nederland op alle niveaus verbeterd kan worden, zodat deze zorg voor iedereen toegankelijk…
-
Lopende projecten
Lees hieronder meer over de lopende onderzoeksprojecten van het Leiden Leadership Centre.
-
Understanding the ecology of the Bornean Pygmy Elephant (Elephas maximus borneensis) in the Sebuku Forest, Nunukan District, North Kalimantan
What is movements and corridors of the Bornean pygmy elephant in Sebuku forest? What is the nature of human-elephant conflict in Nunukan District in time and space? What are the diets of the Bornean elephants related to crop raiding?
-
Iber Kasehatan in Sukamiskin: Utilisation of the Plural Health Information and Communication System in the Sunda Region of West Java, Indonesia
This study has been carried out in the community of Sukamiskin, a kelurahan (‘village’) in Bandung, the Capital of West Java Province, located in the Sunda Region of Indonesia.
-
Regiegroep
De volgende medewerkers maken deel uit van de Academia in Motion Regiegroep.
-
Health Governance
Groeiende gezondheidsongelijkheid, stijgende zorgkosten, de vergrijzing en het tekort aan zorgpersoneel zijn maar een paar voorbeelden van uitdagingen waar de gezondheidszorg voor staat, in Nederland en daarbuiten. Deze vraagstukken vragen om antwoorden die voortkomen uit een interdisciplinaire aanpak,…
-
Sheltering 10 billion people in a warming and resource-scarce world: challenges and opportunities
Sheltering is an immediate human need and determines well-being andhealth.
-
Structure and substructure in the stellar halo of the Milky Way
Promotor: K.H. Kuijken
-
Impacts of grassland wildfire on invertebrate species
Does a mid-season fire impact invertebrate populations?
-
Star formation and aging at cosmic noon: the spectral evolution of galaxies from z=2
Promotores: Prof.dr. M. Franx, Prof.dr. P.G. van Dokkum (Yale University)
-
Star-Forming Galaxies at the Cosmic Dawn
Promotor: Prof.dr. M. Franx, Co-Promotor: Rychard Bouwens
-
LUMC-Campus Den Haag gaat voor een gezondere regio
Hoe kunnen we met Population Health Management de burgers van Den Haag helpen om gezond te worden en te blijven? Deze vraag stond dinsdag 15 januari centraal tijdens de 5e werkconferentie van de LUMC-Campus Den Haag. Ruim 150 artsen, onderzoekers, docenten, zorgprofessionals, bestuurders en beleidsmakers…
-
diagnostic management of suspected pulmonary embolism in special patient populations
Promotie
-
Peer coaching as a population approach to increase physical activity in older adults
Promotie
-
Unfolding the regulation of stress response pathways upon liver injury
Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.
-
Microbial communities in Pampa soils; impact of land use changes, soil type and climatic conditions
Promotor: J.A. van Veen, Co-promotor: E.E. Kuramae
-
Invertebrates on the edge
What invertebrates live in the fields and edges? Do the populations change with landscape complexity?
-
Kearifan Kesehatan Lokal: indigenous medical knowledge and practice for integrated nursing of the elderly with cardiovascular disease in Sumedang
The different kinds of cultural perspectives on health and disease of the participants are related to their knowledge, beliefs, values and practices manifested in various forms of lifestyle in Indonesia. The cultural diversity of the population is also related to differences in health behaviour.
-
Breeding birds on organic and conventional arable farms
Promotor: G.R. de Snoo
-
Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantation - a delicate balance
Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius
-
Monitoring drought and salinity stress in agriculture by remote sensing for a sustainable future
Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…
-
Fungi of the greening Arctic: compositional and functional shifts in response to climatic changes
Promotor: E.F. Smets Co-promotor: J. Geml
-
Faint Quasars at Very Low Frequencies
In this thesis, we use low-frequency and high-frequency radio observations to address the following questions regarding quasars: is the radio loud/quiet quasar dichotomy real?
-
A radio view of dust-obscured star formation
Within the field of astronomy, understanding how galaxies grow and evolve from the Big Bang to the present day is a challenging and complex question.
-
Withstanding the cold: energy feedback in simulations of galaxies that include a cold interstellar medium
Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…
-
Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)
-
Exploitation of host chemokine signalling by pathogenic mycobacteria
Promotores: A.H. Meijer, H.P. Spaink
-
Cheating belowground interactions
Mycoheterotrophy is a particular mode of life in which plants obtain carbohydrates from their associated fungal partners, instead of by using photosynthesis.
-
The impact of obesity on the pharmacokinetics of drugs in adolescents and adults
Promotores: C.A.J. Knibbe; J.N. van den Anker, Co-promotores: H.P.A. van Dongen; B. van Ramshorst
-
Comparative biology of common and grey seals along the Dutch coast : stranding, disease, rehabilitation and conservation
Promotores: H.A. Udo De Haes, P.M. Brakefield