20 zoekresultaten voor “aggregates” in de Publieke website
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Analysis of sub-visible particles in complex injectable formulations
Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik
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Natural and non-natural factors influencing Alzheimer´s Aβ
Promotor: Prof.dr. J.P. Abrahams
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Exploring and exploiting the mechanism of mycelial pellet formation by Streptomyces
Promotor: G.P. van Wezel
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Novel analytical approaches to characterize particles in biopharmaceuticals
Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).
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Pharmaceutical Aspects of Subvisible Particles in Protein Formulations
Promotor: W. Jiskoot, Co-promotor: A. Hawe
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Putting a spin on it: amyloid aggregation from oligomers to fibrils
This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.
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China’s industrial carbon emissions: Historical drivers at the regional and sectoral levels and projections in light of policy
This thesis studied in depth the energy use and CO2 emissions of the industrial sector in China.
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Quantitative Super-Resolution Microscopy
Promotor: T. Schmidt
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Squaramide-based supramolecular polymers : from self-assembly to in vivo application
The aim of this thesis is to develop and study a robust and adaptable scaffold for supramolecular polymer self-assembly in water.
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In vitro investigation of the photoprotection mechanism of Light Harvesting Complex II
Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.
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Methods and Tools for Mining Multivariate Time Series
Mining time series is a machine learning subfield that focuses on a particular data structure, where variables are measured over (short or long) periods of time.
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Recommended weighting methods
The project falls in the context of the EU Thematic Strategy on the Sustainable Use of Natural Resources (COM(2005)670). The Institute for Environment and Resources (IES) of the Joint Research Centre (JRC) has developed three sets of decoupling indicators. Such indicators require the definition of a…
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A computational study of structural and excitonic properties of chlorosomes
The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…
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China’s industrial carbon emissions: Historical drivers at the regional and sectoral levels and projections in light of policy targets
Has the industrial sector in China effectively been decarbonizing in recent years, across different regions and subsectors, and is it plausible that it will reduce its CO2 emissions in conformity with national and internationally pledged emission goals?
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Cities, migration and global interdependence 1350-2000
The research programme Cities, Migration and Global Interdependence 1350-2000 (CMGI) focuses on urbanisation, migration, and economic development in a comparative and global context.
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Nieuwe behandelingen om spierziektes te bestrijden
Biofysicus Alireza Mashaghi gaat samen met zijn collega’s de strijd aan tegen spierdystrofie: genetische aandoeningen die spierziektes veroorzaken. Ze zijn op zoek naar een oplossing voor het samenklonteren van eiwitten, waarbij gevaarlijke ophopingen ontstaan. Het team ontvangt hiervoor 550.000 euro…
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Natuurkundigen bedenken oplossingen bij Physics with Industry
De autoindustrie verzinkt metaal met installaties die kunnen gaan vibreren, waardoor de laag zink op het metaal niet overal even dik is. Zo kan een auto bijvoorbeeld gaan roesten. Fysici zochten naar oplossingen van vijf vraagstukken tijdens de workshop Physics with Industry.
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Hoefijzervormige ‘Parkinsoneiwitten’ vormen klonten
Er is weer nieuws over het eiwit alpha-Synucleine. dat een belangrijke rol wordt toegedicht bij de ziekte van Parkinson. Biofysicus Martina Huber e.a. laten zien op welke manier deze eiwiten samenklonteren als ze met een membraan in contact komen. Hun artikel in de Journal of the American Chemical Society…
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Piepkleine deeltjes bouwen zelfstandig complexe structuren
Kleinere computerchips, smallere cameraatjes; ze worden steeds moeilijker om te maken. Maar wat als de bouwstenen zichzelf opbouwen? Natuurkundige Daniela Kraft bedacht een methode om deeltjes aan te sturen in samenklonteren. Publicatie in ACS Nano.
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Research Seminar Series
For questions and suggestions regarding the series, please contact prof. dr. Olaf van Vliet or dr. Max van Lent