1,995 zoekresultaten voor “development 26 disease” in de Publieke website
-
Relevantie project
Naast het feit dat angstproblemen veelvoorkomend zijn en het daarom belangrijk is om hier effectieve preventieve programma’s en behandelingen voor te ontwikkelen, is dat in deze tijd extra relevant.
-
Comparative biology of common and grey seals along the Dutch coast
What are the main factors associated with the stranding of the two seal species? What are the factors influencing the prevalence of disease in the two species? Which human-related factors influence the populations of the two seal species?
-
Nucleosome stacking in chromatin fibers probed with single-molecule force- and torque-spectroscopy
In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.
-
SMALL Savannah : an information system for the integrated analysis of land use change in the Far North of Cameroon
Promotores: W.T. de Groot, M. Tchuenté, Co-promotor: J.P. Cheylan
-
Cities, migration and global interdependence 1350-2000
The research programme Cities, Migration and Global Interdependence 1350-2000 (CMGI) focuses on urbanisation, migration, and economic development in a comparative and global context.
-
Policy Review on Decoupling
Development of indicators to assess decoupling of economic development and environmental pressure in the EU-25 and AC-3 countries.
-
Security Studies
Security is key to survival for any living organism: life is full of perils and threats, both physically, environmentally, and societally. Security challenges such as terrorism, natural disasters, and cybercrime rank among the most pressing issues of our time, affecting the security and safety of millions…
-
Religie en het milieu
De temperaturen stijgen en de weerpatronen worden steeds onstabieler, de hoeveelheid plastic in de oceanen groeit, diersoorten sterven uit, poolkappen smelten, landbouwgrond wordt onbruikbaar en drinkvoorraden nemen af. Steeds vaker horen we in de media dit soort verontrustende berichten. Op de meest…
-
Synthetic carbohydrate ligands for immune receptors
One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.
-
Bloomington Grove Kickapoo Creek Restoration to Enhance Biodiversity
Does a high quality prairie restoration in an urban/agricultural landscape provide invertebrates necessary for a sustainable ecosystem?
-
RNA splicing in breast cancer progression
In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.
-
Functionalized two-dimensional membranes and materials for solar-to-fuel devices: a multiscale computational approach
In the current global context, there is a pressing need to address sustainable energy supplies to safeguard our Planet and its ecosystems. The choices made by human society have a significant impact on genetic evolution and climate.
-
X-ray spectroscopy of merging galaxy clusters
This thesis focuses on the X-ray spectral analysis of merging galaxy clusters and the plasma code development for future high-resolution X-ray spectroscopy observations.
-
Predicting the future: Predictive control for astronomical adaptive optics
The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.
-
Analysis of Energy Systems
The Institute of Environmental Sciences has carried out and participates in several projects that deal with the analysis of energy systems.
-
Synthesis and applications of cell wall glycopolimer fragments from Staphilococci and Enterococci
Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…
-
Materials Innovative Technologies Assessment (MIN-TEA)
How can prospective LCA be streamlined in a way that its practical application in research and technology development increases?
-
Design, synthesis and application of paramagnetic probes for protein structure studies
The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.
-
Pharmacology based toxicity assessment: towards quantitative risk prediction in humans
Promotor: Prof.dr. M. Danhof
-
Caging ruthenium complexes with non-toxic ligands for photoactivated chemotherapy
The main goal of the research described in this thesis was the development of new photoactivated chemotherapy (PACT) ruthenium(II) complexes bearing a non-toxic photolabile ligand.
-
Self-Adjusting Surrogate-Assisted Optimization Techniques for Expensive Constrained Black Box ProblemsBagheri, S.
Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.
-
Temminck's Order. Debates on Zoological Classification: 1800-1850
“Temminck’s Order” is the scientific biography of Coenraad Jacob Temminck (1778–1850), a Dutch naturalist and the first director of ’s Rijks Museum van Natuurlijke Historie in Leiden.
-
Novel formulations and delivery strategies for inactivated polio vaccines : new routes with benefits
This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.
-
Synthesis of Ribitol Phosphate based Wall Teichoic acids
Antibiotic resistance, caused by widespread use of antibiotics, leads to bacterial infections that are difficult, if not impossible, to treat and is a major worldwide health concern.
-
Onderwijs
De programmagroep Leer- en Gedragsproblemen in het Onderwijs is verantwoordelijk voor onderwijs op het gebied van leerproblemen binnen de bachelor- en masteropleidingen van het Instituut Pedagogische Wetenschappen.
-
Inhibitors and activity-based probes for β-D-glucuronidases, heparanases and β-L-arabinofuranosidases
Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.
-
SDG Report
The following report discusses a survey on the topic of the Sustainable Development Goals that was distributed among researchers at Leiden University in the month of November 2021.
-
Biomimetic models of [NiFe] hydrogenase for electrocatalytic hydrogen evolution
The growing demand of energy indicates that global energy resources in the form of fossil fuels will not be sufficient in the future. In order to solve potential future energy problems development of a sustainable hydrogen economy is highly desirable.
-
Visualization of Vitamin A Metabolism
Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.
-
Exploring novel regulators and enzymes in salicylic acid-mediated plant defense
Salicylic acid (SA) is a plant hormone, which is involved in the defense responses to pathogens and to abiotic stress, and in the regulation of plant growth and development.
-
Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman
-
The role of the Arabidopsis AHL15/REJUVENATOR gene in developmental phase transitions
This thesis describes the functional analysis of the Arabidopsis AHL15 gene.
-
Affinity-based profiling of the adenosine receptors
The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.
-
Ecology of the Ethiopian wolf in a changing landscape: Human carnivore interactions in Afroalpine ecosystems of Ethiopia
Do Ethiopian wolves change their diet and foraging strategy in the landscape under different land uses? How land use affect Afro-alpine rodent Communities? How important are Afro-alpine natural resources utilisation for local livelihoods? What is the human perception of conflict in the Afro-alpine a…
-
Docent Academische Vaardigheden
Wiskunde en Natuurwetenschappen, Instituut Biologie Leiden (IBL)
-
Assistant/Associate professor in Quantitative Ecology (0.8-1.0 fte)
Wiskunde en Natuurwetenschappen, Centrum voor Milieuwetenschappen Leiden (CML)
-
Pre- and perinatal risk factors
Effects of maternal smoking, premature birth, intra-uterine growth retardation and asphyxia on child development.
-
Probing quantum materials with novel scanning tunneling microscopy techniques
This thesis described the development of novel scanning tunneling microscopy techniques to investigate strongly correlated electronic states in quantum matter.
-
Sociology of Policy in Practice (MSc)
De masterspecialisatie Sociology of Policy in Practice biedt de mogelijkheid om een onderzoeksstage te doen om het beleid van een bedrijf of organisatie in de praktijk te bestuderen..
-
Visual Ethnography (MSc)
In de masterspecialisatie Visual Ethnography leer je de kneepjes van het vak om etnografisch onderzoek met audiovisuele methodes te doen.
-
Contact
Wij zijn gevestigd in het Pieter de la Courtgebouw van de Faculteit der Sociale Wetenschappen van de Universiteit Leiden.
-
Sandra van Dijk helpt nierpatiënten gezonder te leven
Hoe kunnen nierpatiënten geholpen worden een gezonde leefstijl aan te nemen? Gezondheidspsycholoog Sandra van Dijk gaat dit onderzoeken met een persoonsgebonden subsidie van de Nierstichting.
-
EUniWell Open Lecture Series | From knowledge transfer to personal development
Lezing, Lezing onderdeel van serie
-
The Sand Motor - Building with Nature to optimise coastal protection and other ecosystem services
How can mega sand nourishments, such as the Sand Motor, be designed and managed for optimal ecosystem services provision ?
-
Carolina Jost
Hoe gebruik je 26.000 opnamen van één zebravisje in het onderwijs?
-
Big Data in ontwikkelings- en humanitaire hulp: een volgende stap in het privacydebat
Hoe kan ‘Big Data’ worden ingezet bij ontwikkelings- en humanitaire hulp en wat zijn de risico’s daarvan? De Universiteit Leiden en United Nation’s Global Pulse organiseren hierover op 23 oktober in Den Haag een internationale expert meeting.
-
Informatie voor scholen
Goede studievoorlichting en kennismaking met wetenschap: de Universiteit Leiden helpt scholen, docenten en decanen graag hiermee.
-
Leidse sterrenkundigen schrijven IEEE Software Impact column
De eer was aan Professor Simon Portegies Zwart en doctor Jeroen Bédorf om voor het blad IEEE Software te schrijven.
-
Osteoprotegerin, a double-edged sword in osteoarthritis development
Promotie
-
Bone and joint disorders: Screening and early clinical drug development
Promotie