918 zoekresultaten voor “human potential” in de Publieke website
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The rebound effect through industrial ecology’s eyes : the case of transport eco-innovation
Promotor: Prof. dr. Arnold Tukker & Prof. dr. René Kemp (Maastricht University)
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Biophysical characterization of membrane protein-small molecule interactions
Promotor: Prof.dr. M. Ubbink
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Controlling growth and morphogenesis of the industrial enzyme producer Streptomyces lividans
Promotor: G.P. van Wezel, Co-Promotor: E. Vijgenboom
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Life Cycle Assessment-Based Guidance for development of New Energy Technologies
The development of new environmentally sound technologies is seen as a key route towards achieving sustainability.
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Fate, accumulation and impact of metallic nanomaterials in the terrestrial environment
The rapidly increasing commercial application of metallic nanoparticles within products will inevitably enhance the amount of NPs being released into soil.
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Noonan and LEOPARD syndrome in zebrafish: molecular mechanisms and cardiac development
Promotor: Prof.dr. J. den Hertog
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Impact of low-carbon electricity development on carbon emissions in China
Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.
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Biomimetic models of [NiFe] hydrogenase for electrocatalytic hydrogen evolution
The growing demand of energy indicates that global energy resources in the form of fossil fuels will not be sufficient in the future. In order to solve potential future energy problems development of a sustainable hydrogen economy is highly desirable.
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The endocannabinoid system in zebrafish larvae
In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.
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Self-assembly of flexible and rigid structures: from colloidal molecules to lattices
Self-assembly offers a promising route to create complex structures and materials using simple building blocks. Through, colloidal self-assembly, we can understand the governing principles of the self-assembly process and unlock its potential in diverse applications in materials science, photonics and…
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Development of a Kidney-on-a-Chip Model for Compound Screening and Transport Studies
Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…
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Single cell mechanics for disease biology and pharmacology
In this thesis, we describe the potential of cell mechanical phenotyping for immune cell characterization, diagnosis, drug testing, as well as treatment of disease.
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Arguably augmented reality : relationships between the virtual and the real
This thesis is about augmented reality (AR). AR is commonly considered a technology that integrates virtual images into a user’s view of the real world.
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Postdoc Computational Modeling for Drug Safety Prediction
Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)
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Human Rights and Global Diversity
Lezing, Opening Owadaleerstoel
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Impacts of the use of Natural Resources and Products
Development of an aggregated impact indicator to measure decoupling.
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Copper trispyrazolylborate complexes for ethene detection
Promotor: E. Bouwman, Co-Promotor: S. Bonnet
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Online Course International Law in Action: A Guide to the International Courts and Tribunals in The Hague
This course explains the functions of each international court and tribunal in The Hague. On the basis of cases and interviews with judges and lawyers, this course explores the role of these courts and tribunals and their potential to contribute to global justice.
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Towards High Performance and Efficient Brain Computer Interface Character Speller: Convolutional Neural Network based Methods
A P300-based Brain Computer Interface character speller, also known as P300 speller, has been an important communication pathway, under extensive research, for people who lose motor ability, such as patients with Amyotrophic Lateral Sclerosis or spinal-cord injury because a P300 speller allows human-beings…
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Prediction of brain target site concentrations on the basis of CSF PK: impact of mechanisms of blood-to-brain transport and within brain distribution
Promotor: M. Danhof, Co-promotor: E.C.M. de Lange
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Waste Collection Systems Assessed and Good Practices Identified (COLLECTORS)
What is the environmental impact of different waste collection systems across Europe? How can the collection be improved when considering collection, sorting, and treatment, as well as use options for secondary materials?
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Preclinical validation of putative targets in cardiovascular and metabolic disease
Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.
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Discovery of Reversible Monoacylglycerol Lipase Inhibitors
Monoacylglycerol lipase (MAGL) is the principal enzyme responsible for hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-AG). MAGL inhibition provides several potential therapeutic opportunities, including anti-nociceptive, anti-inflammatory and anti-cancer activity.
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Spatiotemporal building stock modeling for residential decarbonization in the Netherlands
Decarbonizing the building stock is critical for realizing the climate-neutral target for the Netherlands.
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Systematics, Epidermal defense and Bioprospecting of Wild Orchids
This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.
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Ab initio molecular dynamics calculations on reactions of molecules with metal surfaces
Promotor: Prof.dr. G.J. Kroes
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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Resolving the building blocks of galaxies in space and time
We investigate the buildup of galaxies from various vantage points. The first two chapters focus on the stellar content of galaxies, especially the distribution of stellar masses at birth and potential variations therein in various galactic environments.
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Boosting the host immune system to fight tuberculosis
New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.
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Cancer chess: molecular insights into PARP inhibitor resistance
The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…
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Simulating the birth environment of circumstellar discs
Circumstellar discs are the reservoirs of gas and dust that surround young stars and have the potential to become planetary systems.
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LCA of Printed and E-paper Documents
Comparing the global warming potential (GWP) of the service provided by an iRex Digital Reader to the same service provided by an office printer using a scanning LCA.
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Mariana Gkliati voorzitter bij ‘Europe on Trial'
Op 2 juni heeft Mariana Gkliati deelgenomen aan het debat ‘Europe on Trial' in De Balie.
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Triple bottom line approach for risk-benefit analysis of genetically modified crops
Description of Triple bottom line approach for risk-benefit analysis of genetically modified crops.
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Towards the development of synthetic vaccines against tuberculosis
The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.
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Imaging polarimetry for the characterisation of exoplanets and protoplanetary discs. Scientific and technical challenges
Promotor: Prof.dr. C.U. Keller
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Inverse design of curvature-sensing antiviral peptides
Viral diseases constitute one of the major challenges in modern medicine. Membrane-targeting have broad-spectrum potential and could distinguish viral membranes from the host cell plasma membrane by the difference in membrane curvature.
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The Monetary Valuation of Water-related Ecosystem Services
While ecosystems have concrete benefits for human society, these benefits are typically overlooked in decision-making.
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A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
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Do Intersex & Transgender Children Have Human Rights?
Lezing
- Filosofie van de mensenrechten
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Inhibitors and activity-based probes for β-D-glucuronidases, heparanases and β-L-arabinofuranosidases
Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.
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Heb je nog vragen over de masterspecialisatie Applied Neuroscience in Human Development? Neem dan gerust contact met ons op!
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Cardiomyocytes from human induced pluripotent stem cells
Promotie
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Functional study of the human genome
Promotie
- Symposia 2023-2024
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Data-driven donation strategies: understanding and predicting blood donor deferral
The research in this dissertation aims to optimise blood donation processes in the framework of the Dutch national blood bank Sanquin. The primary health risk for blood donors is iron deficiency, which is evaluated based on donors' hemoglobin and ferritin levels.
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Macro-level assessment of environmental implications of changes to circularity
How to ensure the environmental and economic benefits of circularity transition at macro-scale?
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Placebo onderzoek: Farmacologische conditionering
Het belangrijkste doel is het onderzoeken van de mogelijkheid om het lichaam te leren een soortgelijke fysiologische (autonome, neuro-endocriene of immuunsysteem) en fysieke (b.v. desensibilisatie van hardnekkige lichamelijke symptomen) reactie te laten vertonen op placebomedicatie als op actieve medicatie…