1,694 zoekresultaten voor “mathematical and statistical modelling” in de Publieke website
-
Wout Broekema op de website van Platform O: Zijn experts 'heilig'?
In het bestrijden van de coronacrisis leunen politici in verregaande mate op de kennis van experts. Dat is verstandig, maar het is niet aan experts om politieke besluiten te nemen. Dit betogen Wout Broekema, Universitair Docent Crisis Governance aan de Universiteit Leiden, en Beatrice de Graaf, Hoogleraar…
-
Sofia Express
In Sofia Express gaat Jan Paul Hinrichs op zoek naar de literaire geheimen van de Bulgaarse hoofdstad Sofia, een stad waarin detectives, spionage en andere intriges nooit ver weg zijn.
-
Unmasking the Term 'Dual Use' in EU Spyware Export Control
Dit artikel illustreert hoe de term 'dual use' geassocieerd is geraakt met een bredere dichotomie tussen 'legitieme' en 'illegale' doeleinden.
-
therapy coming of age: Mechanistic insight and rAAV assays on mouse & human retinal organoid models
Promotie
- Statistics Workshop: All hands on Stata
-
Preclinical and ‘near-patient’ models for the evaluation of experimental therapy in prostate and bladder cancer
Promotie
-
Carlos Felipe Blanco Rocha
Wiskunde en Natuurwetenschappen
c.f.blanco@cml.leidenuniv.nl | +31 71 527 4371
-
Ben van Werkhoven
Wiskunde en Natuurwetenschappen
b.j.c.van.werkhoven@liacs.leidenuniv.nl | +31 71 527 2727
-
Piecewise deterministic Markov processes: an analytic approach
Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans
-
Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
-
The holographic glass bead game: from superconductivity to time machines
Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm
-
Cryptography from quantum uncertainty in the presence of quantum side information
Promotor: Ronald Cramer, Co-promotor: Serge Fehr
-
Internationalisering en diversiteit
Laat je op deze pagina inspireren door best practices van onderwijsvernieuwende voorbeelden die in ons onderwijs invulling geven aan de ambitie Internationalisering en diversiteit.
-
Computed fingertip touch for the instrumental control of musical sound with an excursion on the computed retinal afterimage
Promotor: Prof.dr. S. Haring
-
Self adjuvanting immunopeptides: Design and synthesis
Chapter 2 describes a post-synthetic methodology to introduce a fluorescent label in highly lipophilic, Pam3Cys based conjugates.
-
evolutionary changes in allocation to growth, defense, competitive ability and regrowth of invasive Jacobaea vulgaris
Promotor: Prof.dr. P.G.L Klinkhamer, Co-promotor: K. Vrieling
-
The galaxy–dark matter connection: a KiDS study
In this thesis, the research focuses on the properties of dark matter and dark matter haloes and how they connect with the galaxies we can observe in the Universe.
-
Ab initio molecular dynamics calculations on reactions of molecules with metal surfaces
Promotor: Prof.dr. G.J. Kroes
-
Modulation of the immune system for treatment of atherosclerosis
Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.
-
X-ray spectroscopy of interstellar dust: from the laboratory to the Galaxy
In this thesis, we present new laboratory data of interstellar dust analogues.
-
Vertebrate automated screening technology (VAST)
Hoe kun je met robots en automatische herkenning van microscopische beelden uitzonderlijk snel het effect van medicijnen testen?
-
Flows of six heavy metals
Can we provide the Dutch government with an integrative framework, wherein the various policies can be placed and the need for further measures can be identified?
-
The Open Society and Its Animals
Op 10 oktober 2019 verdedigde Janneke Vink haar proefschrift 'The Open Society and Its Animals'. Het promotieonderzoek is begeleid door promotor prof.dr. P.B. Cliteur.
-
The assembly history of the milky way nuclear star cluster
Promotor: P. T. de Zeeuw, Co-promotor: N. Neumayer; G. van de Ven
-
Activity-based protein profiling in drug discovery
In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.
-
Strategies for the improvement of genome editing in Arabidopsis thaliana
Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.
-
CD8+ T-cells in atherosclerosis: mechanistic studies revealing a protective role in the plaque microenvironment
Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.
-
Genetic and environmental factors determining heterogeneity in preservation stress resistance of Aspergillus niger conidia
Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.
-
Inverse Jacobian and related topics for certain superelliptic curves
To an algebraic curve C over the complex numbers one can associate a non-negative integer g, the genus, as a measure of its complexity.
-
Exploring the chemical space of post-translationally modified peptides in Streptomyces with machine learning
The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.
-
wavefront sensors for direct exoplanet imaging: Theory, simulations and on-sky demonstrations
One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…
-
Development and application of cryo-EM tools to study the ultrastructure of microbes in changing environments
Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…
-
The use of computational toxicology in hazard assessment of engineered nanomaterials
Assessing the risks of engineered nanomaterials (ENMs) solely on the basis of experimental assays is time-consuming, resource intensive, and constrained by ethical considerations (such as the principles of the 3Rs of animal testing). The adoption of computational toxicology in this field is a high p…
-
Dynamics of the Oort Cloud and Formation of Interstellar Comets Santiago Torres Rodriguez
The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.
-
Transcultural Health Care Utilisation in Serengeti of Tanzania: Towards Applied Ethnoscience in Public Health Management
The research provides insight into disease behavior in both rural and semi-urban areas in Serengeti in Tanzania.
-
Linkages of Sustainability
Exploring linkages between energy and material use and implications for sustainable development.
-
Consultatie bij fiscale wetgeving
Voor het verbeteren van de kwaliteit van fiscale wetgeving en het fiscale wetgevingsproces: een consultatiemodel. Het model kan als hulpmiddel dienen om bij de totstandkoming van fiscale wetgeving de optimale consultatievariant en de geschikte stakeholders te kiezen.
-
Mining the kinematics of discs to hunt for planets in formation
Detecting planets during their formation stages is crucial for understanding the history and diversity of fully developed planetary systems like our own. However, observing young planets directly is challenging because they are often deeply embedded within their host protoplanetary discs, rich in gas…
-
Stock-driven Scenarios on Global Material Demand
The role of material production as a driver of environmental impacts is increasing, which calls for a better understanding of global material flows. This thesis explores the role of in-use stocks of products, buildings and infrastructure as a key driver of global material demand and discusses the implications…
-
Strategy Dynamics
In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.
-
Spatial populations with seed-bank
In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…
-
T-CYCLE EPR: Development at 275 GHz for the study of reaction kinetics & intermediates
A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.
-
Synthetic, Physical and Computational Chemistry of Propeller-shaped Polycyclic Aromatic Hydrocarbons
This thesis systematically studies the physicochemical properties of non-planar, propeller-shaped, polycyclic aromatic hydrocarbons. The synthesis of several so-called propellerenes is described on a gram scale, using optimized procedures aimed at using less hazardous reagents and reducing the amount…
-
Science based business
Science Based Business (SBB) verbindt de domeinen wetenschap, bedrijfsleven en beleid. Wetenschappelijk onderzoek waar we ons in Leiden op richten, bijvoorbeeld op het gebied van kunstmatige intelligentie, belooft onze samenlevingen ten goede te komen. Het vertalen van wetenschap naar positieve maatschappelijke…
-
A computational study of structural and excitonic properties of chlorosomes
The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…
-
eLaw - Centrum voor Recht en Digitale Technologie
eLaw - Centrum voor Recht en Digitale Technologie- onderzoekt de rol van het recht in de informatiemaatschappij: hoe kan het recht bijdragen aan een goede werking van informatie- en communicatietechnologie, en het gebruik ervan door burgers, bedrijven en overheden?
-
Masterclass Politieke Stijl
Alle politici en bestuurders zijn anders, zelfs al zijn ze van dezelfde partij. Wat kan helpen een bestuurder snel te doorgronden is het archetypemodel van Carola Schoor: zes bestuursstijlen, zes politieke identiteiten. Duik dieper in het denken, doen en presenteren van verschillende soorten leiders…
-
De mysteries van exoplaneten en superzware zwarte gaten: twee Vici-beurzen voor de Sterrewacht
De een ontrafelt het ontstaan van de grootste zwarte gaten in het universum, de ander onderzoekt de invloed van sterrenwind op de atmosfeer van exoplaneten. Zowel Elena Maria Rossi als Aline Vidotto ontvangen een Vici-beurs voor hun onderzoek naar de mysteries van het heelal. ‘Ik heb nog geen idee hoe…
-
Mastermind spelen om Alzheimer te ontrafelen
Om het ziekteverloop van de Ziekte van Alzheimer beter te begrijpen, is volgens Frédérique Kok een strategische en gestructureerde aanpak nodig: de Mastermindmethode. Met haar LUF-subsidie wil Kok data van hoge kwaliteit verzamelen om een wiskundig model maken dat het ontstaan van de ziekte kan herkennen…
-
Organisational & Entrepreneurial Behaviour
De onderzoeksgroep Organizational & Entrepreneurial Behavior onderzoekt het gedrag van individuen en groepen die in organisaties werken, organisaties starten, of organisaties leiden, met als doel om organisatorische praktijken te informeren. Door zich te concentreren op het gedrag van (groepen) werknemers,…