777 zoekresultaten voor “working 20from 20home” in de Publieke website
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
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Computational modeling of angiogenesis : from matrix invasion to lumen formation
Promotor: Roeland M.H. Merks
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Services on Environmental Statistics and Accounts
What is the best way to combine the environmental and economic data and how can we create an operational system to do so, thereby supporting the delivery of data to the Data centres on Products and Resources?
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Insights into the mechanism of electrocatalytic CO2 reduction and concomitant catalyst degradation pathways
This work describes several studies into the electroreduction of carbon dioxide (CO2RR), both regarding mechanistical aspects and catalyst stability considerations. Mechanistic insights into carbon-carbon bond formation on a silver catalyst are described in Ch 2, were we find an acetaldehyde-like surface…
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The role of the tumor suppressor Lkb1 in energy homeostasis
The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.
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Soil legacy effects on aboveground plant-insect interactions
In this thesis, the role of plant-mediated soil legacy effects in shaping aboveground plant-insect interactions was investigated.
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Giant unilamellar vesicles: An efficient membrane biophysical tool and its application in drug delivery studies
Promotor: A. Kros
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SDG Report
The following report discusses a survey on the topic of the Sustainable Development Goals that was distributed among researchers at Leiden University in the month of November 2021.
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Mechanistic studies of the water oxidation reaction with molecular iron catalysts
In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.
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The Ecology and Evolution of Microbial Warfare in Streptomyces
The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.
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Breaking & Entering: PAH photodissociation and top-down chemistry
Laboratory, observation and modeling work on the dissociation of polycyclic aromatic hydrocarbons in interstellar environments and the formation of new molecular species through the fragmentation process.
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Deep Hanging Out in the Age of the Digital; Contemporary Ways of Doing Online and Offline Ethnography
A brief review essay on some of the work that has been recently published in the emergent field of digital ethnography.
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Online Course International Law in Action: Investigating and Prosecuting International Crime
This course provides an insider perspective into the work of international criminal courts and tribunals. You will learn about the investigation and prosecution of international crimes in The Hague.
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Online Course The Rooseveltian Century
This course uses the lives, ideals and achievements of Theodore, Franklin, and Eleanor Roosevelt to create the idea of a Rooseveltian century. It is an invitation to think critically and historically, and it wants to give you a glimpse of what it means to be a historian at work.
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Tijdschrift 'East European Politics'
Het tijdschrift 'East European Politics' publiceert artikelen over politiek, bestuur en internationale betrekkingen van de post-communistische landen.
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Public Administration
Public Administration is a major refereed journal publishing articles on public administration, public policy and public management.
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The use of activity based protein profiling to study proteasome biology
Promotor: H.S. Overkleeft, Co-Promotor: B.I. Florea
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Tijdschrift 'Res Publica'
Res Publica een Nederlandstalige wetenschappelijk tijdschrift voor politieke wetenschap, bestuurskunde, Europese en internationale politiek, politieke sociologie en communicatiewetenschap.
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Regional Federal Studies
Regional & Federal biedt een wetenschappelijk platform aan wetenschappers die zich bezighouden met internationaal onderzoek op deze gebieden.
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Acta Politica
Acta Politica is het officiële wetenschappelijke tijdschrift van de Nederlandse Kring voor de Wetenschap der Politiek.
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Full Professor 'Clinical Developmental Psychology'
Sociale Wetenschappen, Psychologie
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Postdoctoral researcher in Supramolecular Chemistry
Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)
- PhD Candidate: Investigating Palaeolithic sheltering solutions in East Central Europe (1.0 FTE)
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Refined tautological relations on moduli spaces of curves
The key purpose of this project is to study tautological relations on the level of closed differential forms or even integral cochains (i.e. we don't take classes in cohomology).
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SCS Courses
The coursework within the Science Communication and Society (SCS) specialisation prepares students for internships and a career in communication about science and health.
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The Demographics of Protoplanetary Disks: from Lupus to Orion
The work presented in this thesis is based on ALMA surveys of protoplanetary disks in three star-forming regions: Lupus, OMC-2, and NGC 2024.
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Novel pharmacometric techniques to quantify the pharmacodynamics of analgesics
The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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Sustaining Ethical Aquatic Trade (SEAT)
Creating a framework to assess the sustainability of fish farms which will set sustainability standards and give consumers information about the the sustainability and safety of their seafood.
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Data-Driven Machine Learning and Optimization Pipelines for Real- World Applications
Machine Learning is becoming a more and more substantial technology for industry.
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Photothermal circular dichroism studies of single nanoparticles
In this work, we investigate the minute circular dichroism effects of single nanoparticles.To this aim, we apply photothermal imaging with a polarization-modulated heating beam.
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Research
The mission of our group is understanding how science communication works to improve the interaction between science and society. We believe better science communication can improve our society and engage many different groups with science, also improving science.
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De volmaakte beschouwer
PhDArts co-director Dr. Janneke Wesseling’s e-book ‘De volmaakte beschouwer, De ervaring van het kunstwerk en receptie-esthetica’ was recently published. The key question of the book is: how does the work of art work?
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The spin evolution of accreting and radio pulsars in binary systems
Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.
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Abiotic depletion in LCIA
Possible improvements for the assessment of abiotic depletion in LCA.
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Controverse in de les
Met dit project wordt van een evidence-based onderwijsmethodiek (toolkit) ontwikkeld voor docenten van alle vakgebieden in het hoger onderwijs voor het effectief omgaan met controversiële onderwerpen in de les.
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Towards a mechanistic understanding of nanoparticle behavior using zebrafish
The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.
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Metals in the diffuse gas around high-redshift galaxies
Promotores: Prof.dr. J. Schaye & Prof.dr. C. Steidel (California Institute of Technology)
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Random walks on Arakelov class groups
The main topic of this PhD thesis is the Arakelov ray class group of a number field, an algebraic object that contains both the ideal class group structure and the unit group structure.
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Peptide-based probes for protein N-Methyltransferases
The work described in this thesis focuses on the development of linear or cyclized peptide probes against protein N-methyltransferases to characterize their specific binding behavior, providing further binding details for inhibitory activity study.
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A molecular journey : tales of sublimating ices from hot cores to comets
The thesis explores how interstellar chemistry evolves as a function of time and changing physical architectures during the formation of stars.
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Search and rescue: tackling antibiotic resistance with chemistry
With the rise of multi-drug resistant bacterial pathogens, the possibility of a post-antibiotic world is quickly becoming reality.
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Health, Ageing and Society (Msc)
Discover the master program Health, Ageing and Scoiety at Leiden University and contribute to a future proof health care system. Read more.
- From basic research to therapy development for neuromuscular disorders
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CfP: ADAM: 'Addressing Difficult Aspects of the Medieval' (Oxford, September 23-24)
A workshop is organized at St John's College, Oxford, on September 23-24. The workshop aims to bring together medievalists of all disciplines to discuss the research and teaching of ‘difficult’ or ‘taboo’ topics. The organizers welcome applications from scholars working in any field that demands sensitivity…
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Research Seminar Series
For questions and suggestions regarding the series, please contact prof. dr. Olaf van Vliet or dr. Max van Lent
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Assistant professor "Inflammation pathways in atherosclerosis"
Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)
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Professional learning of vocational teachers in the context of work placement
Promotie
- Spring School Medieval and Early Modern Studies: Landscape History and Ecology
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Onderzoekers
In dit interdisciplinaire onderzoeksprogramma werken onderzoekers uit vijf verschillende disciplines met elkaar samen. Zij stellen zich hieronder (in het Engels) aan u voor.