347 zoekresultaten voor “chemical industry” in de Publieke website
-
Electrocatalysis of CO2/CO interconversion and Hydrogen Evolution in Bicarbonate Buffers
Bicarbonate buffer is largely found in nature due to its ability to regulate pH variations around neutral values. As the pH changes, so does the speciation of the buffer.
-
Zipping into Fusion
Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros
-
Quantum computation with Majorana zero modes in superconducting circuits
Promotor: Prof.dr. C.W.J. Beenakker
-
Protoplanetary disk anatomy: examining the structure and chemistry of planetary birthplaces with simple molecules
This thesis examines the link between simple molecules and the underlying structure and chemistry within protoplanetary disks - the birthplaces of planets.
-
Bridging the gap between physics and chemistry in early stages of star formation
A dense region of a gaseous and dusty cloud collapses to form a protostar surrounded by a disk and an envelope. This thesis uses both observations and models to study physical and chemical conditions of these protostellar systems which are likely where planets start to form.
-
Antibiotic Discovery: From mechanistic studies to target ID
The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.
-
Stereoelectronic and conformational effects in oxocarbenium, iminium and iminosugar ammonium ions
Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée
-
Giant unilamellar vesicles: An efficient membrane biophysical tool and its application in drug delivery studies
Promotor: A. Kros
-
Development of highly accurate density functionals for H2 dissociation on transition metals
Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).
-
Sensing Transport
Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.
-
Applications of Natural Deep Eutectic Solvents to Extraction and Preservation of Biomolecules
The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.
-
Synthetic Study on ADP-ribosylation
This Thesis focuses on the design and synthesis of ADP-ribosylated compounds that can be applied in biological studies.
-
The puzzle of protoplanetary disk masses
My work focuses on a class of astronomical objects called protoplanetary disks.
-
Omics data integration with genome-scale modelling of dopaminergic neuronal metabolism
Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.
-
Matter into context: population- and community-level impacts of nanomaterials in freshwater ecosystems
The application of nanomaterials in industrial processes and consumer products provides many societal benefits, but can also lead to the release of nanomaterials into the environment. The work in this dissertation aims to provide insights into the potential environmental impacts that may follow from…
-
Activity-based protein profiling of glucosidases, fucosidases and glucuronidases
Promotores: H.S. Overkleeft, G.A. van der Marel, Co-promotor: B.I. Florea
-
Compiling and Refining Environmental and Economic Accounts (CREAA)
CREEA is a FP7 project on compiling and refining environmental and economic accounts. The project runs from April 2011 to March 2014.
-
Multi-objective Evolutionary Algorithms for Optimal Scheduling
Multi-criteria optimalisatie is een effectieve techniek voor het vinden van optimale oplossingen die een afweging bieden tussen verschillende, tegenstrijdige criteria. Het heeft zijn toepassing gevonden in de wereld om ons heen omdat bij het oplossen van praktische, re¨ele wereld problemen men gewoonlijk…
-
EPCEM 2001: Differences in the authorization process of GMOs in the EU and the USA
This report investigates the different approaches in the authorization process of GMOs for commercial use in the European Union and the United States of America. Three main aspects are considered and analyzed as potential causes of differences in the authorization process of GMOs for commercial use.…
-
Evaluating Asian aquaculture using Life Cycle Assessment (LCA)
Are there significant differences among the environmental impacts resulting form the production of Asian aquaculture commodities and what are the main causes for these?
-
New Foundations for Separation Logic
The research presented in this thesis concerns one of the most important questions in software engineering of our time: how can we make sure that software is free from memory safety bugs?
-
The Infrared Spectrum of Massive Protostars
We have conducted a full spectral line survey of the 3-13 micron region of two massive protostars, AFGL 2591 and AFGL 2136, for the first time at high spectral resolution.
-
The holographic glass bead game: from superconductivity to time machines
Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm
-
Global distribution patterns of distinct mycorrhizal types and ecological drivers of these patterns
What are the global relationships between environmental conditions and abundance of distinct types of mycorrhizal fungi in soil and plant roots?
-
Parallel evolution in an invasive plant species: evolutionary changes in allocation to growth, defense, competitive ability and regrowth of invasive
Promotor: Prof.dr. P.G.L Klinkhamer, Co-promotor: K. Vrieling
-
Ab initio molecular dynamics calculations on reactions of molecules with metal surfaces
Promotor: Prof.dr. G.J. Kroes
-
X-ray spectroscopy of interstellar dust: from the laboratory to the Galaxy
In this thesis, we present new laboratory data of interstellar dust analogues.
-
The formation of complex organic molecules in dense clouds-Sweet results from laboratory
Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.
-
Electrocatalytic CO2 reduction toward liquid fuels : on heterogeneous electrocatalysts and heterogenized molecular catalysts
With the energy transition toward a renewable energy supply and a CO2-neutral economy, electrification of the energy system is rising in importance, which leads to the challenge of long-term storage of renewable electricity.
-
Lava worlds: characterising atmospheres of impossible nature
Over the last three decades, the discovery of exoplanets has revealed the boundless variety of worlds beyond our own Solar System. Majority of planetary systems contain short-period planets that are larger than Earth but smaller than Neptune.
-
Direct and two-step activity-based profiling of proteases and glycosidases
Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel
-
The use of computational toxicology in hazard assessment of engineered nanomaterials
Assessing the risks of engineered nanomaterials (ENMs) solely on the basis of experimental assays is time-consuming, resource intensive, and constrained by ethical considerations (such as the principles of the 3Rs of animal testing). The adoption of computational toxicology in this field is a high p…
-
Sterrewacht Leiden
Sterrewacht Leiden is het sterrenkundig instituut van de Faculteit der Wiskunde en Natuurwetenschappen van de Universiteit Leiden.
-
Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
-
Abiotic depletion in LCIA
Possible improvements for the assessment of abiotic depletion in LCA.
-
Inhibitor Selectivity: Profiling and Prediction
Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.
-
Postdoc Computational Modeling for Drug Safety Prediction
Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)
-
Thomas Bäck
Wiskunde en Natuurwetenschappen
t.h.w.baeck@liacs.leidenuniv.nl | +31 71 527 7108
-
2 PhD Candidates, Reinforcement Learning for Sustainable Energy
Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)
-
Development of novel anti-cancer strategies utilizing the zebrafish xenograft model
In this thesis, we will utilize embryonic zebrafish tumour models to understand the interaction between engrafted human cancer cells and macrophages from the host, test drug administration modalities and anti-cancer efficacies of newly-developed PDT and PACT compounds, and test a light-triggered liposomal…
-
Onderzoeksgroep Governance of Crises
De onderzoeksgroep ‘Governance of Crises’ bestudeert verschijnselen, dynamiek en spelers als het gaat om crisisbeheersing. Het Crisis Research Center (CRC) van de Universiteit Leiden maakt deel uit van deze onderzoekgroep.
-
Development of an Adverse Outcome Pathway (AOP) for metallic nanoparticles
What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?
-
PROGENY
How do you make a technology sustainable that does not even exist yet? Well, by bringing together an interdisciplinary team of pioneering European experts right at the start and paying attention to sustainability right from the development phase.
-
Improving vegetation representation in Multi-sensor Earth Observation Products through phenology and trait-based priors
What are the behaviours of plant traits throughout various points in the growing season in a radiative transfer model framework and how well can this knowledge be integrated through data assimilation to provide priors for robust local and global vegetation products and analysis?
-
Metals in LCIA
A critical look at the impact assessment modelling of metals in Life Cycle Impact Assessment and improvement options.
-
Less is more: reduced mycelial heterogeneity for improved production of enzymes and antibiotics
Hoe kan de techniek van cell wall engineering worden ingezet zodat de industrie streptomyceten beter kunnen verwerken tot nieuwe antibiotica?
-
NanoFeed
Do selenium nanoparticles in fish food cause subtle alterations in behavior of fish: effect of particles size and concentration?
-
GLOBOX
GLOBOX is a spatially differentiated multimedia fate, exposure and effect model. It is used for the calculation of spatially differentiated LCA characterisation factors on a global scale.
-
Pathogenese en therapie van kanker
Bij kanker groeien lichaamscellen ongecontroleerd. Het gedetailleerd in kaart brengen van hoe dit precies gebeurt maakt het mogelijk om efficiënte therapieën te ontwikkelen. Onderzoekers van het Leids Universitair Medisch Centrum (LUMC) en de Universiteit Leiden werken samen aan het vermeerderen van…
-
Pesticides and health – challenges and opportunities for exposure assessment
The aim is to develop methods to assess environmental and occupational exposure to (individual) pesticides, to be applied in epidemiological studies investigating pesticide exposure and human health. Furthermore, we aim to investigate the potential association between exposure to pesticides and Parkinson’s…