379 zoekresultaten voor “clinical psychology” in de Publieke website
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Genetic and clinical pharmacology studies in GBA1-associated Parkinson's disease
Promotie
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HLA epitopes in kidney transplantation: from basic science to clinical application
Promotie
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Measurement of cortical, nerve, and muscle excitability in early phase clinical drug development
Promotie
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Analysis of sarcoma and non-sarcoma clinical data with statistical methods and machine learning techniques
Promotie
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on shared decision-making for depression and anxiety disorders in clinical practice
Promotie
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mass spectrometry for kidney injury biomarker translation towards the clinical laboratory
Promotie
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Genetic and clinical aspects of inherited syndromes associated with adenomatous polyposis
Promotie
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“Special Needs by Placebo”: Programme to Advise, Normalize And Control its European Administration (PANACEA)
Hoewel veel beroepsbeoefenaren in de gezondheidszorg aangeven vaak gebruik te maken van placebo-effecten en de mechanismen ervan, is er weinig formele training over hoe om te gaan met placebo- en nocebo-effecten in de klinische praktijk. Dit project wil deze kloof tussen wetenschappelijke kennis over…
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Internationale topstudenten ontvangen LExS-beurs
In het Academiegebouw werden op 5 september de internationale studenten welkom geheten die een LExS-beurs van de Universiteit Leiden kregen. De 50 studenten ontvingen een certificaat dat hun beurs symboliseert.
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First-pass and systemic metabolism of cytochrome P450 3A substrates in neonates, infants, and children
Growth and development affect the metabolism of drugs administered to neonates, infants, and children.
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Diagnosis and treatment of obese children with insulin resistance
Promotors: C.A.J. Knibbe, Anthonius de Boer, Co-promotor: M.M.J. van der Vorst
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High-throughput profiling of small molecules using mass spectrometry
Promotor: Prof.dr. T. Hankemeier
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Time is of the essence: investigating kinetic interactions between drug, endogenous neuropeptides and receptor
Promotor: A.P. IJzerman Co-promotor: L.H. Heitman
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Metabolomics assisted with stable-isotope labeling: exploring neuronal metabolism related to Parkinson’s disease
The progressive loss and degeneration of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD). The onset and progression of PD can be triggered by multiple risk factors, for instance, genetic mutation, environmental exposure, and aging.
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Zebrafish xenograft model: identification of novel mechanisms driving prostate cancer metastasis
Prostate cancer (PCa) is one of the most prevalent cancer in males.
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Chemical biology of glucosylceramide metabolism fundamental studies and applications for Gaucher disease
This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).
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Liposome-based synthetic long peptide vaccines for cancer immunotherapy
Promotores: Wim Jiskoot; Ferry Ossendorp
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Ginsenosides as selective glucocorticoid drugs: agonists, antagonists, and prodrugs
Glucocorticoids are potent anti-inflammatory drugs widely used clinically to treat various inflammatory and immune conditions. However, two main clinical problems limit their use. GCs trigger severe side effects and they induce acquired glucocorticoid resistance, especially during chronic systemic treatment…
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Analytical chemistry and biochemistry of glycosphingolipids: new developments and insights
Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…
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Dynamics of the renin-angiotensin aldosterone system in dogs: circadian variations in physiological conditions and in relation to angiotensin-converting
Promotor: Prof.dr. M. Danhof
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The road to insurmountability: Novel avenues to better target CC Chemokine receptors
This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.
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Towards a system-based pharmacology approach to predict developmental changes in renal drug clearance in children
Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)
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Uncovering vulnerabilities in triple-negative breast cancer
Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.
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Modulation of leukocyte homeostasis in atherosclerosis
Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel
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The interplay between lipids and the immune system in atherosclerosis
Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.
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Novel regulators of prostate cancer stem cells and tumor aggressiveness
Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper
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The role of glomerular filtration and active tubular secretion in predicting renal clearance in children using population pharmacokinetic and
In this thesis population pharmacokinetic and physiologically-based pharmacokinetic (PBPK) approaches were applied to investigate the influence of glomerular filtration (GF) and active tubular secretion (ATS) on renal clearance in children.
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Quantitative pharmacology of antimicrobials
Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.
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Synthesis of Ribitol Phosphate based Wall Teichoic acids
Antibiotic resistance, caused by widespread use of antibiotics, leads to bacterial infections that are difficult, if not impossible, to treat and is a major worldwide health concern.
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Ruthenium-peptide conjugates for targeted phototherapy
As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.
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Towards predictive cardiovascular safety: a systems pharmacology approach
Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski
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PLGA-based particulate vaccine delivery systems for immunotherapy of cancer
Promotores: W. Jiskoot, F. Ossendorp
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Systems pharmacology of the amyloid cascade
According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).
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Stress-induced modulation of the innate immune system in cardiovascular disease
Promotor: Prof.dr. J. Kuiper
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The ins and outs of ligand binding to CCR2
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman
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Algorithms for the description of molecular sequences
Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros
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Protein arginine methyltransferases as modulators of lipid metabolism and inflammation and the relevance for atherosclerosis
Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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Single-cell immune profiling of atherosclerosis: from omics to therapeutics
Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…
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Psychologie (BSc)
De bacheloropleiding Psychologie in Leiden is een brede studie met een focus op onderzoek.
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Methodologie en Statistiek
Methodologie & Statistiek richt zich op de ontwikkeling, evaluatie en toepassing van modellen voor de analyse van psychologische onderzoeksgegevens.
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Studie-informatie van alle vakken
Ons onderwijsaanbod is breed en divers. Hieronder vindt u alle informatie over de vakken die door de afdeling Bedrijfswetenschappen worden verzorgd. Als u op een vak klikt, wordt u doorgeleid naar de studiegids.
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Klinische Psychologie
Klinische psychologie richt zich vooral op de toepassing van wetenschappelijke psychologische kennis op assessment, preventie en behandeling van psychopathologie.
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Onderwijs
Methodologie & Statistiek verzorgt bachelorcursussen en een masterspecialisatie.
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Sociale, Economische en Organisatiepsychologie
Sociale, Economische en Organisatiepsychologie richt zich vooral op de toepassing van wetenschappelijke psychologische kennis op het gebied van sociale processen binnen en tussen groepen mensen en individuen, in organisaties, maar ook bij het maken van economische en consumentenbeslissingen.
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Raising the bar for classification and outcome assessment for clinical studies in axial spondyloarthritis
Promotie
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OSCoffee: The psychology of biases, and how they influence us as scholars
Lezing
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FNV- subsidie voor psychologisch onderzoek naar effect basisinkomen
De psychologen Fenna Poletiek en Erik de Kwaadsteniet krijgen van vakbond FNV een subsidie om te onderzoeken hoe mensen zich gaan gedragen ten opzichte van werk als ze een basisinkomen krijgen. Hoe gaan ze op zoek naar een antwoord?
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'Zonder empathie geen goede zorg'
Een patiënt die zich begrepen voelt herstelt sneller. Maar hoe kan een arts zich beter inleven? Door literaire werken te lezen, stelt de Leidse emeritus hoogleraar medische psychologie, Ad Kaptein. Hij bespreekt er 26 in het boekje ‘Helende woorden – romans over ziek-zijn’.