The plant hormone auxin regulates plant growth and development through polar cell-to-cell transport-generated maxima and minima. PIN FORMED (PIN) auxin efflux carriers determine the direction of this auxin flow through their asymmetric placement on the plasma membrane (PM).

This dissertation was to develop effective graphene-based nanofluidic devices by developing scalable fabrication methods and elucidating proton transport mechanisms.

This interdisciplinary minor addresses sustainabilty challenges from a systems perspective, and investigates ways to sustain society within planetary boundaries.

How do you engage society to stop biodiversity loss? How do you create political and social involvement to deal with climate change? And how do you balance the economic needs of industry with the negative effects of pollution? If you find these kinds of questions interesting, then this Pre-University…

Promotor: C. W. J. Beenakker, Yu. V. Nazarov, Co-promotor: J. Tworzydlo

Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

De Sustainable City Map dient als een uitgebreide gids om een duurzame levensstijl in de stad te bereiken. Of je nu nieuw bent in de stad of gewoon op zoek bent naar groenere keuzes, deze kaart heeft voor ieder wat wils!

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

Ontdek de bachelor Science for Sustainable Societies aan de Universiteit Leiden. Bekijk de video en leer hoe wetenschap bijdraagt aan duurzame oplossingen!

Promotor: Prof. dr. Arnold Tukker & Prof. dr. René Kemp (Maastricht University)

Single-layer graphene (SLG) has attracted considerable interest as a proton exchange membrane for direct methanol fuel cells (DMFCs), owing to its atomic thickness, mechanical robustness, and unique proton permeability.

The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.

Wil jij het verschil maken voor onze planeet? Wil je oplossingen voor milieuproblemen vinden die écht impact hebben? Vind je dat natuurwetenschappen en sociale wetenschappen moeten samenwerken om zo de complexe duurzaamheidsvraagstukken van onze tijd aan te pakken? Dan is de bachelor Science for Sustainable…

In-use stocks of products can be considered as intermediaries between human needs and the physical world.

This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.

Het volgende rapport bespreekt onze enquête over de UN Sustainable Development Goals die werd verspreid onder onderzoekers aan de Universiteit Leiden in november 2021.

Studievoorlichting

Endocannabinoids are lipid messengers that modulate various physiological functions by activating the cannabinoid CB1 and CB2 receptors. While the metabolism of endocannabinoids and their action at the CB receptors is fairly well studied, the molecular mechanisms governing their release and transport…

In times of hardships or crisis, local people know how to deal with it using their resourcefulness. Although efforts are sometimes made by the government to help them, they are fully aware that community support is at least equally important.

The interest of this thesis lies in spin transport in normal metals and superconducting half-metallic junctions.

This thesis describes a study from both a theoreticaL and an experimental point of view.

Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen

In this thesis, classes of strongly interacting quantum field theories, have been studied.

Global Environmental Extensions Multi-Regional Input-Output (EE-MRIO) analysis is often used to analyze how changes in global and national demand for products lead to socioeconomic and environmental impacts at the national level.

Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.

Supply risks are not new. But the aggravation of power conflicts on the international stage coupled with global shifts towards energy transition and digitalization has triggered the next supply risk research era.

What is the optimal design of sandy solutions for sustainable climate change adaption, from an ecological, biophysical and societal point of view?

Promotor: G.R. de Snoo, Co-promotor: H.H. de Iongh, C.J.M. Musters

A framework for prospective/ex-ante life cycle assessment (LCA) and ecological risk assessment (ERA) of emerging technologies is developed and applied to a case study of III-V/silicon photovoltaic panels.

The studies in this thesis are focused on the physical effects in the flat band materials. The results contain the discovery of strong enhancement of RKKY spin-spin interactions with specific geometric arrangement and dynamical generation of excitonic order parameter with high magnitude.

Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

Transport inspectorates are looking for novel methods to identify dangerous behavior, ultimately to reduce risks associated to the movements of people and goods. We explore a data-driven approach to arrive at smart inspections of vehicles.

Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…

Promotor: M. Danhof, Co-promotor: E.C.M. de Lange

This study attempts to understand how indigenous community institutions pose an important role in sustainable community-based development, including the integration between local culture and development.

The project seeks to develop an eco-design framework for single-use medical devices and packaging

EnSMiRT wil de expertise binnen de alliantie Una Europa benutten en de samenwerking tussen toonaangevende onderzoekers die in verschillende stadia van de minerale waardeketen werken, stimuleren om deze dringende uitdagingen rechtstreeks aan te pakken.

There is an increasing amount of attention on EU and its Member States contributions to implementation of two landmark agreements: the Paris Climate Agreement and the UN Agenda 2030 with Sustainable Development Goals (SDGs). Absent from the current literature is an analysis of the political effect of…

This thesis focuses on enhancing predictions of central nervous system drug exposure using the LeiCNS-PK3.0, a physiologically based pharmacokinetic model.

Despite being the second largest transmembrane protein family after GPCRs, the SLC superfamily has only gained significant attention in early drug development over the past decade.

Promotor: S.M. Verduyn Lunel

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

Luchtvaart is een mondiale kwesitie. Toch zijn er maar weinig landen die de veiligheid van passagiers echt kunnen garanderen.

I will give a general introduction to the field of molecular electronics, its history, methods and challenges. I will also introduce the subject of my investigation and provide a brief outlook to the remainder of our thesis.

This thesis examines enzyme domain architecture and engineering to improve the breakdown of lignocellulose and starch, abundant biopolymers crucial for sustainable biofuel and biochemical production. Carbohydrate-active enzymes (CAZymes) facilitate this degradation, but the structural complexity of…

Thermodynamics is one of the founding scientific pillars that has helped us better understand heat engines, biology, ecosystems, and even black holes. While it fundamentally describes large systems by examining the bulk behavior of their constituents, it is anchored in the statistical equivalence of…

Op 9 juni 2020 verdedigde Maral Darouei haar proefschrift 'Managing a sustainable career in the contemporary world of work: Personal choices and contextual challenges'. Het promotieonderzoek is begeleid door promotor prof.dr. J.I. van der Rest.

IoT technology poses serval opportunities to supply chains. This thesis employs grey correlation and forecasting models, system dynamics, agent-based modeling, and ex-ante LCA to investigate and quantify the opportunities and risks of IoT-enabled sustainable supply chain operations from both industrial…

Prof.dr. Gert Jan Kramer is bij de Faculteit Wiskunde en Natuurwetenschappen in deeltijd benoemd tot hoogleraar Sustainable Energy. Kramer is en blijft daarnaast manager Energy Futures bij Shell. Tot zijn aantreden in Leiden was Kramer hoogleraar bij de TU Eindhoven.