418 zoekresultaten voor “global gene regulation” in de Publieke website
-
The Ecology and Evolution of Microbial Warfare in Streptomyces
The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.
-
UN 2.0: Ten Innovations for Global Governance 75 Years beyond San Francisco
Dr. Joris Larik, universitair docent vergelijkend, EU- en internationaal recht bij LUC The Hague, is coauteur van het rapport 'UN 2.0: Ten Innovations for Global Governance 75 Years beyond San Francisco'.
-
A New Model of Global Governance in International Tax Law Making (GLOBTAXGOV)
Dr. Irma Mosquera Valderrama onderzoekt in haar ERC-project de rol van de OESO (Organisatie voor Economische Samenwerking en Ontwikkeling) en de EU bij de totstandkoming van internationale fiscale wetgeving en streeft ernaar voorwaarden te scheppen waaronder zowel ontwikkelde landen als ontwikkelingslanden…
-
Discovery and exploitation of the transcriptional regulatory system of pectinases in Aspergillus niger
Pectin is a plant cell wall polysaccharide made of mainly D-galacturonic acid (GA) subunits. The potency of the filamentous fungus Aspergillus niger to naturally secrete high amounts of pectinases to degrade pectin has been utilized for the industrial production of pectinases.
-
Addressing climate change with behavioural science: A global intervention tournament in 63 countries
Dit artikel beschrijft het ontstaan van een app die kan helpen om het klimaatbewustzijn en de actie wereldwijd te vergroten.
-
Evolution and development of orchid flowers and fruits
To gain more insight into the evolutionary development of orchid flowers and fruits, the orchid species Erycina pusilla was studied. The evolutionary origin of the median petaloid sepal, the callus on the labellum, and the stelidia was studied.
-
Sarah Wolff
Faculteit der Geesteswetenschappen
s.wolff@hum.leidenuniv.nl | +31 71 527 2698
-
Conference on Private law and market regulation georganiseerd door de onderzoeksgroep Coherent Privaatrecht
Op vrijdag 2 december 2016 heeft een internationale onderzoeksconferentie plaatsgevonden in Leiden. Deze was georganiseerd door de onderzoeksgroep van Coherent Privaatrecht. De conferentie droeg de titel “Private law and market regulation – interaction, interference or inconsistency?”. Het centrale…
-
Going global to local: achieving agri-food sustainability from a spatially explicit input-output analysis perspective
The global agri-food system plays a critical role in food security and environmental issues.
-
Upcoming Research Conference on Private law and market regulation in Leiden
Op vrijdag 2 december vindt in Leiden een internationale, multidisciplinaire conferentie plaats gecentreerd rond onderzoek over burgerlijk recht en marktregulering. De conferentie draagt de titel “Private law and market regulation – interaction, interference or inconsistency?” en wordt georganiseerd…
-
Global fitness maximising approaches to evaluate the trade-offs involved in the evergreen and deciduous conundrum
Which traits and/or trade-offs determine benefits of being deciduous or evergreen?
-
Global metabolomics and lipidomics approaches to probe virus-host interactions
The outbreaks of AIDS and COVID-19 showed clearly how infectious viruses can influence people’s lives. Investigating the changes in the host metabolism may provide a paradigm shift to consider immune-metabolic interactions as therapeutic targets.
-
Understanding disease suppressive soils
Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.
-
Precision modeling of breast cancer in the CRISPR era
The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.
-
Disentangling drought-responsive traits with focus on Arabidopsis
In recent decades, climate change has led to more frequent and severe drought events, causing serious consequences such as increased forest mortality and significant crop yield losses. Understanding how drought affects plants, especially economically important herbaceous species, is crucial for predicting…
-
The role of the tumor suppressor Lkb1 in energy homeostasis
The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.
-
Structural changes in single chromatin fibers induced by tension and torsion
Promotor: T. Schmidt, Co-promotor: S. J.T. van Noort
-
Strategies for the improvement of genome editing in Arabidopsis thaliana
Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.
-
Nieuwe decaan Faculteit Governance and Global Affairs
Het College van Bestuur heeft besloten prof. dr. Kutsal Yesilkagit met ingang van 1 januari 2016 voor een periode van 3 jaar te benoemen tot decaan van de Faculteit Governance and Global Affairs.
-
Close-out Netting: A comparative study of English, French and US laws in a global perspective
Op 1 december 2020 verdedigde Bernadette Muscat haar proefschrift 'Insolvency Close-out Netting: A comparative study of English, French and US laws in a global perspective'. Het promotieonderzoek is begeleid door promotoren prof.mr.drs. M. Haentjens en prof.mr. B. Wessels.
-
The Local Impact of a Global Court: Assessing the Impact of the International Criminal Court in Situation Countries
Op 9 januari 2019 verdedigde Marieke Wierda haar proefschrift 'The Local Impact of a Global Court: Assessing the Impact of the International Criminal Court in Situation Countries'. Het promotieonderzoek is begeleid door promotoren prof. dr. C. Stahn en prof.dr. L.J. van den Herik.
-
PhD Position on Understanding the Global Movement for Open Research Information
Sociale Wetenschappen, Centrum voor Wetenschaps- en Technologiestudies
-
Modulating the behaviour of pancreatic tumour cells
Promotores: Prof.dr. M.K. Richardson, Prof.dr. H.P. Spaink. Co-promotor: C.P. Bagowski
-
Directeur UN Global Pulse bezoekt Faculteit
Robert Kirkpatrick, directeur van UN Global Pulse, bezocht de Faculteit der Wiskunde en Natuurwetenschappen op dinsdag 27 oktober 2015.
-
Nucleosome stacking in chromatin fibers probed with single-molecule force- and torque-spectroscopy
In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.
-
Discovery of novel Antibiotics from Actinomycetes by Integrated Metabolomics & Genomics Approaches
Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi
-
Trans-kingdom DNA transfer
The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.
-
Histone-DNA assemblies in archaea. Shaping the genome on the edge of life
All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).
-
Faculteit Campus Den Haag wordt Faculteit Governance and Global Affairs
De Faculteit Campus Den Haag krijgt per 1 januari 2016 een nieuwe naam: Faculteit Governance and Global Affairs. Deze nieuwe naam is een logische samenstelling van de componenten van deze faculteit.
-
Lovende recensies expositie Global Imaginations
Nederlandse kranten schrijven lovend over de lustrumexpositie in de Leidse Meelfabriek: ‘Global Imaginations is grappig en confronterend’. De tentoonstelling vindt plaats ter ere van het 440-jarig bestaan van de Universiteit Leiden en is nog te bezichtigen tot 5 oktober.
-
Onderzoek
The aim of our research program is to better understand the aetiology and course of mood, anxiety and trauma and stressor-related disorders and to test and improve treatments for these disorders.
-
Key innate immune components controlling intracellular infection
Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer
-
Multi-omics studies of the control of growth and antibiotic production of Streptomyces
Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).
-
Citizenship, Migration & Global Transformations: een interdisciplinair onderzoeksprogramma
Een onderzoeksgroep van vijftien mensen uit diverse vakgebieden zoals politieke economie, internationale betrekkingen, rechtsgeleerdheid, geschiedenis en bestuurskunde, werkt samen binnen het interdisciplinaire onderzoeksprogramma 'Citizenship, Migration and Global Transformations'. Voor dit onderzoeksproject…
-
Aquatic eDNA: Beyond Species Presence
As a non-invasive genetic method, eDNA based approaches have become an important component of ecologists' and environmental managers' toolkits for biomonitoring in conservation and an increasingly important source of ecological knowledge.
-
Sheltering 10 billion people in a warming and resource-scarce world: challenges and opportunities
Sheltering is an immediate human need and determines well-being andhealth.
-
Volg het Governance and Global Affairs blog!
Blijf op de hoogte van de ontwikkelingen van de faculteit!
-
De grote uitdaging: think global, act local
De Global Entrepreneurship Week ‘battle of ideas’ is begonnen! Stuur jouw plannen in voor een betere wereld!
-
Valerio Barbarossa
Wiskunde en Natuurwetenschappen
v.barbarossa@cml.leidenuniv.nl | +31 71 527 5656
-
Dynamic organization of bacterial chromatin by DNA bridging proteins
Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.
-
Molecular engineering of plant development using Agrobacterium-mediated protein translocation
Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa
-
Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
-
Vijf vragen over het onderzoeksprogramma Citizenship, Migration and Global Transformations
De onderzoeksteams zijn opgezet, samenwerkingen zijn gestart, projecten afgetrapt, de eerste startsubsidies zijn binnen en de websites zijn in de lucht. Het stimuleringsprogramma Citizenship, Migration and Global Transformations, dat bestaat uit de twee pijlers Social Citizenship and Migration en Global…
-
Nadia Garnefski
Faculteit der Sociale Wetenschappen
garnefski@fsw.leidenuniv.nl | +31 71 527 3774
-
Winifred Gebhardt
Faculteit der Sociale Wetenschappen
gebhardt@fsw.leidenuniv.nl | +31 71 527 4084
-
Transnational counterterrorism assemblages: the case of preventing and countering violent extremism in Mali
In dit artikel wordt onderzocht hoe de dreiging van terrorisme op beleidsniveau is aangepakt door middel van een analyse van een specifiek in Mali.
-
Functions of leptin in tuberculosis and diabetes: multi-omics studies across species
In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.
-
Hybrid zone dynamics in amphibians
Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.
-
Ethiek Commissie Pedagogische Wetenschappen
De Commissie Ethiek heeft als hoofdtaak alle voorgenomen gedragswetenschappelijk onderzoek van het Instituut Pedagogische Wetenschappen, te toetsen op criteria van ethisch verantwoord wetenschappelijk handelen.
-
Chemical genetic approaches for target validation
Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.