Topstukken uit de Universitaire Bibliotheken Leiden

Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…

In the past decade many population studies have been performed with the Atacama Large Millimeter/submillimeter Array (ALMA) to understand the bulk properties of protoplanetary disks around young stars. These population studies mostly consisted of low mass stars, with relatively few of the disks around…

Microglia support the central and peripheral nervous system by forming the first line of defense against hazardous events. Microglia are increasingly acknowledged as critical players in neurodegenerative diseases, highlighting them as potential therapeutic targets.

In-use stocks of products can be considered as intermediaries between human needs and the physical world.

In this project, researchers from computer science, law, psychology, and public administration research in practice how artificial intelligence (AI) can be leveraged to make decision-making in the security domain more effective, while also keeping it safe and accountable.

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

Studeren aan de Universiteit Leiden voor een paar uur per week? Een cursus, of een aantal vakken volgen? Er zijn diverse mogelijkheden voor geïnteresseerden om kennis op te doen bij eenvan de Leidse opleidingen.

Promotor: Prof.dr. H.A.G. Wijshoff

Welke kansen en bedreigingen vloeien voort uit de institutionele en normatieve diversiteit op het terrein van de rechten van de mens voor de effectieve bescherming van die rechten in een wereld die gekenmerkt wordt door pluralisme?

Workshop

Stress komt veel voor in de huidige samenleving. Dit is zorgwekkend, aangezien onderzoek herhaaldelijk heeft aangetoond dat stress een negatieve invloed heeft op de lichamelijke gezondheid. Zo vergroot stress bijvoorbeeld de kans op hart- en vaatziekten.

The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.

This thesis introduces a relational interaction model and a practical tool for describing, visualising and generating interactive dialogues.

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski

This thesis is concerned with the constitution of chiral responsive matrix assemblies that may undergo light-driven conformational changes and self-select vibrations to develop vibronic states for driving semi-classical coherent transfer with nearly 100% yield in a lossless NCAP process.

An interdisciplinary collection of the best international scholarship on Muslim youth.

Dirk Broekhuijsen is op donderdag 16 november 2017 gepromoveerd op zijn proefschrift ‘A multilateral tax treaty: designing an instrument to modernise international tax law’. Zijn promotoren zijn prof. mr. F.A. Engelen en prof. mr. S.C.W. Douma.

Hieratic Papyrology

Mapping the neural mechanisms underlying social motivations of adolescents and adults

Kinase inhibitors are key therapeutic agents, particularly in oncology, yet their clinical efficacy is often hampered by off-target effects and limited understanding of their cellular target profiles.

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

In this thesis chemical and physical processes in the ice mantles on interstellar dust grains are studied.

Irene Khan, expert op het gebied van mensenrechten, werpt een aantal vragen op: Wat kan men verstaan onder een ‘Culture of Justice’? Wie bepaalt wat 'Justice' is? Hoe realistisch is de bevordering van ‘Rule of Law’ en ‘Justice’ in landen waar sprake is van ernstige conflictsituaties en armoede?

Within the field of astronomy, understanding how galaxies grow and evolve from the Big Bang to the present day is a challenging and complex question.

In the emerging field of small-molecule RNA targeting, there is a growing demand for new high-throughput screening methods.

Security and safety challenges rank among the most pressing issues of modern times. Challenges such as cyber-crime, terrorism, and environmental disasters impact the lives of millions across the globe. The course will introduce you to this broad theme in an increasingly complex world.

Het thema 'Health and well-being in a healthy society' is één van de speerpunten van de Faculteit der Sociale Wetenschappen (FSW). We zetten ons in voor het bevorderen van gezondheid en welzijn voor mensen van alle leeftijden.

Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf

Op dinsdag 24 maart is het boek 'The European Public Servant: A shared Administrative Identity?' verschenen.

Make more fluid: In condensed matter systems, electrons can acquire unusual properties from their interaction with the atomic lattice.

Het boek gaat in op de vraag: Hoe en waarom raken mensen betrokken bij het Europese 'homegrown jihadisme'?

Congres/symposium

The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…

De minor Creative Strategies for a Society in Change (CSSC) legt een verbinding tussen het verkrijgen van inzicht in creatieve maakprocessen en het verkennen van maatschappelijke problematieken die kenmerkend zijn voor onze tijd.

Kunst en vrije tijd, Kunst en vrije tijd

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot

Surface acoustic waves (SAWs) are mechanical waves that travel along the surface of a material and find many applications in modern technologies due to the ease of excitation on piezoelectric substrates via interdigital transducers (IDTs).

Almost three years after receiving her honorary doctorate, Dr Graça Machel returned to Leiden University. Over the course of two days she spoke with students, researchers, and other interested persons, about human rights – particularly those of women and children – in a world in which these are continually…

On the largest scale, the Universe resembles a cosmic spiderweb. Most galaxies coexist in small groups within the threads of this web. At the nodes of the threads are enormous groups of galaxies forming the largest structures in the universe still held together by gravity: clusters of galaxies.

In this dissertation, we work towards an experiment in which we aim to bring a micrometer sized magnet at the tip of a soft cantilever into a superposition.

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

Promotor: W.T. de Groot

The zoo of detected exoplanets reveals both the uniqueness of our own Solar System and the complexity of planetary system formation, sparking fundamental questions about how planetary systems form and evolve.

Door tekortkomingen in de regelgeving rond arbeidsomstandigheden lijden piloten en bemanning van luchtvaartmaatschappijen aan vermoeidheid en onvoldoende bescherming. De Leidse promovendus Yuran Shi onderzocht hoe internationaal recht kan helpen om de arbeidsomstandigheden en veiligheid in de luchtvaartsector…