Polycyclic aromatic hydrocarbons (PAHs) are the most abundant class of organic compounds in space. The PAH field evolves from the constant interaction between experimentalists, theorists, modellers and observers. While laboratory research and quantum chemical calculations together set up the molecular…

This Thesis focuses on the design and synthesis of ADP-ribosylated compounds that can be applied in biological studies.

This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.

Promotor: G.R. de Snoo

De masterspecialisatie Philosophical Perspectives on Politics and the Economy van de Universiteit Leiden was voorheen bekend onder de naam Philosophy, Politics and Economics.

Sound is everywhere in the marine environment and hearing is therefore a very important for stimuli for fish. They use sound for orientation and communication, during migration, aggregation and spawning, but also for detection of prey and predators.

This thesis mainly extends the theory of positive operators on Riesz spaces to a setting of pre-Riesz spaces.

In this thesis, we extend the concept of null models as canonical ensembles of multi-graphs with given constraints and present new metrics able to characterize real-world layered systems based on their correlation patterns.

Promotor: P.M. Brakefield

Theresa May houdt vol dat geen Brexit-deal beter is dan een slechte Brexit-deal. Volgens diverse wetenschappers is dit echter niet het geval. Het zou niet alleen slecht zijn voor Groot-Brittannië, maar ook voor Nederland.

A management strategy has been developed for field margins to reduce pesticide drift to non-target areas and to promote biodiversity on arable land. To this end, 3 and 6 m wide strips along the edges of winter wheat, sugar beet and potato crops have been left unsprayed with herbicides and insecticides…

This thesis addresses questions on effectively using variational quantum circuits for machine learning tasks.

This thesis aimed to investigate the impact of exposure dynamics, relative contributions of ENPs(particle) and ENPs(ion), and dosing regimens on the toxicity of ENPs varying in different physico-chemical properties, on the composition and functioning of soil microbial communities.

Promotor: P. Stevenhagen, Co-promotor: R.M. van Luijk

A History of Dutch Corruption and Public Morality toont 300 jaar verandering, continuïteit en diversiteit in de geschiedenis van Nederlandse politieke corruptie en publieke moraliteit. Het analyseert een reeks corruptieschandalen en toont hoe de debatten daarover waren verbonden met de grote veranderingen…

Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.

Microbiome composition of the spermosphere and the rhizosphere of wild and modern bean accessions grown in an agricultural and a native soil from Colombia was characterized by metagenomics and cultivation-dependent approaches.

Promotor: Robert Tijdeman, Co-promotor: Cornelis Kraaikamp

In this thesis we push the boundaries of high-resolution imaging at radio frequencies between 100 and 200 MHz. Using the International LOFAR Telescope that spans across Europe we achieve sub-arcsecond angular resolution.

Op 19 september 2019 verdedigde Lynette Janssen zijn proefschrift 'EU Bank Resolution Framework: A comparative study on the relation with national private law'. Het promotieonderzoek is begeleid door promotoren prof.mr. W.A.K. Rank en prof.mr. M. Haentjens.

This thesis consists of three papers that are centered around the common theme of Hausdorff uo-Lebesgue topologies and convergence structures on vector lattices and on vector lattices and vector lattice algebras of order bounded operators.

The physical origin of the dozens of stellar-mass binaries, the mergers of which have been detected by the LIGO-Virgo-KAGRA collaboration via gravitational waves, is still unknown.

Promotor: Prof.dr. E. Bouwman, Co-Promotor: S. Bonnet

This thesis investigates how non-genetic factors, such as inflammation and concomitant medication, impact hepatic drug metabolism and subsequent drug metabolizing phenotype predictions.

With the emergence of online social networks (OSNs), the way people create and share information has changed, which becomes faster and broader than traditional social media.

Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…

This ecological community has long been known to affect host biology, and their diverse roles have been further clarified in recent years following numerous studies of animal:microbiota interactions in diverse systems.

In this thesis, the role of plant-mediated soil legacy effects in shaping aboveground plant-insect interactions was investigated.

Promotoren: R. Tijdeman, A.K. Lenstra, Co-promotor: H.J.J. te Riele

Promotor: Prof.dr. G.R. de Snoo, Co-promotor: R. Heijungs

D2.2 comprises the in-depth legal analysis of the initial heuristic model, focused on addressing, in more detail, the main legal concerns for data reusers in the European data economy. This detailed analysis of the legal propositions presented in D2.1 is supplemented by an analysis of the technological,…

D1.2 reports on the findings of an analysis of framework conditions relevant in the context of the data economy from a legal, a socio-economic and a technological perspective. The analysis is a key foundation for the creation of an initial, heuristic model of the European data economy. The deliverable…

In this thesis we study the moduli space of genus g curves, and the differential forms that occur naturally on this moduli space.

This dissertation is part of a broader research project that revolves around unraveling the evolution of balanced lethal systems.

Because thin systems can deform along the thickness with relative ease, the interplay between surface mechanics and geometry plays a fundamental role in sculpting their three-dimensional shape.

Software development is a complex process. It is important that software products become stable and maintainable assets.

M.T.M. Koper, Co-promotor: D.G.H. Hetterscheid

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.

Promotores: W.J.G.M. Peijnenburg, G.R. de Snoo, Co-promotor: M.G. Vijver

The experiments described in this thesis employ local lentiviral knockdowns in brain areas of female zebra finches followed by behavioural assays consisting of preference and Go/Nogo tasks.

Feedback van medestudenten op schrijfwerk is net zo leerzaam als die van docenten.

We consider the propagation of electrical signals through nerve fibres.

On dinsdag 26 september heeft Jessica Hill haar proefschrift ‘On the road to adulthood. Delinquency and desistance in Dutch emerging adults’ verdedigd. Promotor is Professor Arjan Blokland.

Promotor: H.V.J. Linnartz

Aan de Universiteit Leiden is een subsidie toegekend door de Koninklijke Nederlandse Akademie voor Wetenschappen (KNAW) en het Ministerie van Onderwijs van de Volksrepubliek China. Het gaat om een subsidie voor een gezamenlijk onderzoeksproject van drie jaar, dat wordt uitgevoerd door het Hazelhoff…

The aromatic infrared bands (AIBs) seen throughout the interstellar medium (ISM) are generally thought to be carried by polycyclic aromatic hydrocarbons (PAHs) and their nitrogen analogues (PANHs).

In light of climate change, it is crucial to determine whether plant species can adapt to future climates to avoid extinction. Plants adapt to various conditions by altering their functional traits, such as leaf size or photosynthetic rate. Some traits appear linked and vary together between species,…

The demand for neodymium-iron-boron (NdFeB) magnets is rapidly growing, while the neodymium supply chain is under pressure. Recycling can alleviate these issues. This thesis investigates the potential for deploying novel magnet recycling technologies and their environmental consequences.

In this thesis, we study different curved single crystals because of the diversity of surface structures across their curvature.