Three major cosmology-focused missions are planned for the next decade: the Euclid space telescope, the Vera C. Rubin Observatory in Chile, and the Nancy Grace Roman Space Telescope.

This thesis applies data mining in commercial settings in the telecommunications industry.

Promotor: F. Arbab

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.

Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe

Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.

Promotor: E. Gittenberger, Co-promotores: L.P. van Ofwegen; B.W. Hoeksema

The redox-conversion reaction of metal-disulfide and metal-thiolate complexes are important, as they may shed light on electron-transfer reactions that often occur in Nature.

The Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles.

Promotor: M.K. Richardson, Co-Promotor: F. Witte

In multi/many-core System-on-Chips (SoCs), the performance is almost linearly scaling with the number of processing elements.

Tracing the evolution of the molecular gas content in galaxies is critical for a complete understanding of galaxy formation and evolution, as it provides the direct fuel for star formation. Studies of high-redshift (z>1) molecular gas reservoirs, most commonly traced by carbon monoxide (CO), have seen…

The project Multimedia Research and Documentation of African Oral Genres: Connecting Diasporas and Local Audiences (Director: D.Merolla) focuses on multimedia as technology that allows scholars to share documentation and scientific knowledge with the cultural owners of the collected oral genres.

Promotores: Wim Jiskoot; Ferry Ossendorp

The research described in this thesis centered on retaining exo-β-glucosidases implicated in health and disease, in particular the human inherited lysosomal storage disorder, Gaucher disease (GD).

International trade has played a major role in defining the modern global economy. Trade, however, entangles the environmental pressures of economic sectors, giving the illusion of environmental improvements, while the opposite may be occurring.

Promotor: E.F. Smets, Co-promotor: J. Geml

Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.

A remarkable population of short period transiting rocky exoplanets with equilibrium temperatures on the order of 2,000 K has recently been discovered.

Promotor: W. Jiskoot, Co-promotor: A. Hawe

Promotores: Prof.dr. G.F.A Kersten, Prof dr. J.A. Bouwstra

The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…

Promotor: A. Kros

Optical projection tomography (OPT) is a tomographic 3D imaging technique used for specimens in the millimetre scale.

Promotor: B.van de Water, Co-promotor: L.S.Price

The electrochemical oxygen reduction reaction (ORR) is an essential half-reaction for the utilization of hydrogen as a sustainable fuel, via the conversion of hydrogen to electrons and protons facilitated by the ORR. In the most common fuel cells, the ORR is requires high loadings of non-abundant platinum…

While ecosystems have concrete benefits for human society, these benefits are typically overlooked in decision-making.

Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier

Tin electrodeposition applications have rapidly evolved in the past 25 years.

This dissertation presents the synthesis and evaluation of antibody recognition for various capsular polysaccharide (CP) fragments of Staphylococcus aureus (S. aureus).

The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.

A large diversity of exoplanetary systems has been found, but it is still unclear what drives this diversity.

Bacteria have the ability to alter their morphology in order to adapt to changing environments.

Studievoorlichting

Promotor: Prof.dr. E.F. Smets, Co-Promotor: L.W. Chatrou

Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik

This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.

Marine sponges are important members of reef ecosystems, as they play ecological roles that are essential for the health of the reef.

In my research, I used a comparative wood anatomical approach to address wood evolution of the (largely) tropical flowering plant families Apocynaceae and Sapotaceae.

Promotor: Prof.dr. B. van de Water

There are many interpretations of quantum mechanics, and ultimately experiments are needed to verify or falsify these interpretations.

An interdisciplinary collection of the best international scholarship on Muslim youth.

Thermodynamics is one of the founding scientific pillars that has helped us better understand heat engines, biology, ecosystems, and even black holes. While it fundamentally describes large systems by examining the bulk behavior of their constituents, it is anchored in the statistical equivalence of…

In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.

Studying the impact of urbanisation on the respiratory health of past Dutch populations (1200-1850 CE).

De onderzoeksvoorstellen van wiskundige Peter Bruin, natuurkundige Daniela Kraft, bio-farmaceut Rawi Ramautar en sterrenkundige Catherine Walsh en nog 7 onderzoeksvoorstellen van talentvolle Leidse wetenschappers zijn gehonoreerd met een Veni-subsidie van 250.000 euro. Landelijk zijn 155 Veni’s vers…

Sekse- en genderverschillen bij diabetes zijn onderbelicht. Meer onderzoek naar en aandacht voor dit thema is gewenst. Dit komt naar voren uit onderzoek van de Leidse gezondheidspsychologen Andrea Evers en Judy Veldhuijzen, samen met Stefanie Meeuwis en Aleksandrina Skvortsova in opdracht van het Diabetes…

Acht jonge wetenschappers van de Universiteit Leiden ontvangen een Rubiconbeurs van wetenschapsfinancier NWO. Hiermee kunnen zij een periode onderzoek doen aan een topinstituut of -universiteit in het buitenland.