1,677 zoekresultaten voor “ronald systems” in de Publieke website
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The LeiCNS-PK3.0 model development and applications: healthy-to-diseased CNS pharmacokinetic translation
Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…
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On metrics and models for multiplex networks
In this thesis, we extend the concept of null models as canonical ensembles of multi-graphs with given constraints and present new metrics able to characterize real-world layered systems based on their correlation patterns.
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Simona Demkova over Enforcement Challenges in Multilevel Regulatory Systems
Op 15 en 16 december nam Simona Demková deel aan een afsluitende conferentie en boekpresentatie van het doctorale opleidingsprogramma van de Universiteit van Luxemburg over ‘Enforcement Challenges in Multilevel Regulatory Systems – DTU REMS.
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Nicolas NavarreWiskunde en Natuurwetenschappen
n.h.navarre@cml.leidenuniv.nl | +31 71 527 2727
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Innate immune modulation in atherosclerosis and vascular
Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax, Co-promotor: I. Bot
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Algorithm design for mixed-integer black-box optimization problems with uncertainty
The increasing competition in the automotive industry requires the tailored, swift development of technologically sophisticated vehicles. Therefore, the computationally expensive state-of-the-art simulation technologies are combined with optimization algorithms. An example of a real-world optimization…
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Adaptive Streaming Applications: Analysis and Implementation Models
Promotor: Prof.dr. E. Deprettere
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Integrating Analytics with Relational Databases
The database research community has made tremendous strides in developing powerful database engines that allow for efficient analytical query processing.
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Gastschrijver
Het gastschrijverschap brengt studenten en docenten in contact met schrijvers van naam en hun vaak eigenzinnige kijk op de wereld. Samen bespreken ze wat het moderne schrijverschap betekent in de praktijk, onderzoeken ze het hoe en waarom van verbeeldingskracht en creativiteit en verkennen ze de ambachtelijke…
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Publieksinterview met gastschrijver Ronald Giphart
Lezing, Publieksinterview
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Improving juvenile justice systems in Europe: Training for professionals
Prof. Ton Liefaard en dr. Stephanie Rap (m.m.v. Apollonia Bolscher LL.M.) zijn betrokken bij het ontwikkelen van een training Toolkit en Manual voor het project Improving Juvenile Justice Systems in Europe: Training for Professionals (JUST/2013/FRC/AG).
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Compressed Σ-Protocol Theory
In analogy to mathematical proofs, the goal of a proof system is for a prover to convince a verifier of the correctness of a claim.
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Over de gastschrijver
Schrijver Ronald Giphart is in 2024 gastschrijver van de Universiteit Leiden.
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Metastability for low-temperature Kawasaki dynamics with two types of particles
Promotor: W.Th.F. den Hollander, Co-promotor: F.R. Nardi
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Linking the gene regulatory network with the functional physical structure of whole-genome engineered Arabidopsis mutants : an HR-MAS NMR-based
Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.
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Semi-partitioned Scheduling and Task Migration in Dataflow Networks
Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov
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Improved hard real-time scheduling and transformations for embedded Streaming Applications
This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.
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Advancing the LeiCNS-PK3.0 model for prediction of CNS Pharmacokinetics Nonlinear BBB Transport, Inter-species Scaling, and Machine Learning
This thesis focuses on enhancing predictions of central nervous system drug exposure using the LeiCNS-PK3.0, a physiologically based pharmacokinetic model.
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Femke Bakker, Hawks and Doves: Democratic Peace Theory Revisited
Femke Bakker, Hawks and Doves: Democratic Peace Theory Revisited
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Exploring future multi-messenger Galactic astronomy
For centuries astronomers studied the Universe by collecting light. Nowadays, we are living in times of great technological advancements, which allow us to explore our Universe in a new way - though gravitational wave radiation.
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Ecological functioning of bacterial chitinases in soil
Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)
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Exploring the interactions of M dwarf winds and cosmic rays
This thesis focus on the interaction between M dwarf stellar winds and Galactic cosmic rays and the possible effects on the habitability of exoplanets.
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Probing quantum materials with novel scanning tunneling microscopy techniques
This thesis described the development of novel scanning tunneling microscopy techniques to investigate strongly correlated electronic states in quantum matter.
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Countering misinformation in the EU: origins, evolution, and prospects
Dit proefschrift onderzoekt de reactie van de Europese Unie op het groeiende probleem van desinformatie. Het gebruikt deze casus om kritisch te analyseren hoe samenlevingen informatie-uitdagingen zoals
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Computer says no - Understanding Digital Authority
To what extent can digital technologies be considered as authorities?
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Novel system-inspired model-based quantum machine learning algorithm for prediction and generation of High-Energy Physics data
De huidige en toekomstige quantumcomputers vormen dezelfde uitdaging als de laser in zijn begindagen. In theorie werd voorspeld dat de laser een bron van zeer speciaal, zeer krachtig licht zou zijn. Maar in die tijd waren er geen duidelijke toepassingen voor. Critici van het idee noemden het een probleem…
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Tracing the journey of the sun and the solar siblings through the Milky Way
Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown
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Environmental opportunities and challenges for IoT technologies in sustainable supply chain operations: from industries to products
IoT technology poses serval opportunities to supply chains. This thesis employs grey correlation and forecasting models, system dynamics, agent-based modeling, and ex-ante LCA to investigate and quantify the opportunities and risks of IoT-enabled sustainable supply chain operations from both industrial…
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Workshop over Access to Justice and the EU’s Remedies System
Op 3 en 4 november 2022 organiseerde Melanie Fink een workshop voor de auteurs van de samengestelde uitgave ‘Access to Justice and the EU’s Remedies System’. Het boek zal naar verwachting begin 2024 verschijnen bij Cambridge University Press.
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Bartolomeus Häussling LöwgrenWiskunde en Natuurwetenschappen
b.j.p.m.haussling.lowgren@cml.leidenuniv.nl | +31 71 527 2727
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Oliver TaherzadehWiskunde en Natuurwetenschappen
o.a.taherzadeh@cml.leidenuniv.nl | +31 71 527 2727
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Docenten
Docenten Academie voor de Rechtsstaat
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Random walks in dynamic random environments
Promotor: W.Th.F. den Hollander
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Development of synthetic procedures towards immunostimulating carbohydrates
Promotor: Prof.dr. G.A. van der Marel, Co-Promotor: J.D.C. Codée
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Fermions and Bosons: Excitons in strongly correlated materials
Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp
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Discrete tomography for integer-valued functions
Promotor: S.J. Edixhoven, Co-promotor: K.J. Batenburg
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Biological model representation and analysis
Promotor: Prof.dr. J.N. Kok, Co-promotor: F.J. Verbeek
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Jennifer AndersonWiskunde en Natuurwetenschappen
j.a.anderson@cml.leidenuniv.nl | +31 71 527 2727
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Lezingen
Tijdens de Leiden Science Family Day worden er vijf lezingen gegeven: twee kinderlezingen en drie lezingen voor volwassenen. Ben jij er bij?
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Prediction of brain target site concentrations on the basis of CSF PK: impact of mechanisms of blood-to-brain transport and within brain distribution
Promotor: M. Danhof, Co-promotor: E.C.M. de Lange
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Long term dynamics of stochastic evolution equations
Promotor: S.M. Verduyn Lunel, Co-promotor: O. van Gaans
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The impact of climate variability on the ecology of a lion (Panthera leo Linnaeus 1758) population and lion livestock conflicts in the Amboseli
Promotor: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Co-promotor: H.H. de Iongh
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Chemical Tools to Illuminate N-acylphosphatidylethanolamine Biosynthesis
This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.
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Het legaliteitsbeginsel en de doorwerking van Europees recht in het Nederlandse materiële strafrecht
Het recht van de Europese Unie beïnvloedt direct en indirect de reikwijdte van strafrechtelijke aansprakelijkheid in Nederland. Die beïnvloeding heeft betekenis voor het materieelrechtelijk legaliteitsbeginsel.
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Visualizing strongly-correlated electrons with a novel scanning tunneling microscope
Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.
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Don't Blink: Detecting transiting exoplanets with MASCARA
This thesis describes the Multi-site All-Sky CAmeRA (MASCARA), which consists of two small robotic telescope designed to detect exoplanets around the brightest stars in the sky.
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Metabolic signatures in nutrition and health: short-term diet response, sexual dimorphism and hormone chronobiology
The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).
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Soil and crop management options to improve nitrogen cycling on dairy farms on peat soil
The main research question of this thesis was: Can nitrogen cycling on dairy farms on peat soil in the Dutch Green Heart area be improved by adapting management to the nitrogen supply from soil and by using other grassland species and crops without affecting milk production?
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Hai LinWiskunde en Natuurwetenschappen
h.x.lin@cml.leidenuniv.nl |
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Piecewise deterministic Markov processes: an analytic approach
Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans