One of the key quests in astronomy is to study the growth and evolution of galaxies across cosmic time. Radio observations provide a powerful means of studying the formation of stars and subsequent buildup of distant galaxies, in a way that is unbiased by the presence of dust.

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

This thesis describes the design and synthesis of fragments of various cell wall carbohydrates of the Streptococcus species, including the branched Group B-specific antigen (GBC) of Group B Streptococcus, glycerol phosphate (GroP) modified group A carbohydrate (GAC), and the O-acetylated type 1 capsular…

Growth hormone profiles are pulsatile and highly variable between individuals, limiting the implementation of mathemathical models to quantify an individual's secretion.

Promotor: M.T.M. Koper, Co-promotor: J.B.F. Juurlink

Promotor: M.T.M. Koper, Co-promotors: A.I. Yanson, L.B.F. Juurlink

Advanced sensing techniques require graphene with high quality and well-controlled surface chemistry.

Promotor: Prof.dr. J. den Hertog

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

The book ‘Bestrijdingsmiddelen en Milieu' gives a transparent overview of facts and figures concerning pesticide use in the Netherlands and the impact of pesticides on the environment.

Global healthcare is on the verge of an antibiotic availability crisis as bacteria have evolved resistance to nearly all known antibacterials. Identifying new antibiotics that operate via novel modes-of-action is therefore of high priority.

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-promotor: B.I. Florea

As leading cause of death worldwide, cancer is responsible for nearly 10 million deaths in 2020 according to World Health Organization (WHO). Cisplatin and its derivatives are commonly used chemotherapy agents for current cancer treatment in the clinics.

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

An interdisciplinary collection of the best international scholarship on Muslim youth.

Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.

Following the Big Bang, structure in the Universe started collapsing under the force of gravity. This resulted in the formation of the first stars, galaxies and clusters of galaxies.

Announcement of the publication of Vamping the Stage: Female Voices of Asian Modernities, the first book-length study of women, modernity, and popular music in Asia (University of Hawai'i Press, 2017).

The physical origin of the dozens of stellar-mass binaries, the mergers of which have been detected by the LIGO-Virgo-KAGRA collaboration via gravitational waves, is still unknown.

Op maandag 1 februari is het tweede semester feestelijk ingeluid op de Sterrewacht. De Afdeling Jeugdrecht en JSV Liberi nodigden twee advocaten uit om te komen spreken over de belangen van de minderjarige in het gezondheids- en vermogensrecht.

Per 1 september 2024 is er geen predicaat cum laude meer voor de master Geneeskunde. Het College van Bestuur besloot onlangs een ontheffing te verlenen voor de faculteit geneeskunde van Universiteit Leiden/LUMC. Het besluit past in de lijn van andere geneeskunde opleidingen in Nederland.

Het was een gezellig drukke middag tijdens de On-campus Master's Experience van de Faculteit Geesteswetenschappen. De informatiesessies en de bijbehorende informatiemarkt vielen goed in de smaak bij nieuwsgierige bachelorstudenten.

Het belangrijkste doel van dit onderzoek is om de steden van het Romeinse Nabije Oosten in de keizertijd in kaart te brengen, met een focus op locatie, stadsgrootte en stedelijke kenmerken, om de vorm van het stedelijke systeem en de niveaus van integratie te bestuderen.

De Universiteit Leiden biedt één volledige Leiden University Excellence Scholarship (LExS) aan aan een Afrikaanse kandidaat die geïnteresseerd is in de tweejarige Research Master African Studies (ResMA AS); het is dus een beurs voor niet-EER/niet-EVA*-aanvragers.

This thesis combines field and laboratory studies to address some of the most pressing questions in the field of microplastic research.

This dissertation is a collection of four research articles devoted to the study of Kummer theory for commutative algebraic groups.

This thesis describes how different colours of light affect various aspects of the growth and development of Arabidopsis and tomato plants⁠.

This thesis provides explicit expressions for the density functions of absolutely continuous invariant measures for general families of interval maps, that include random maps and infinite measure transformations, not necessarily number systems.

In this thesis, we have used numerical approaches to study the effects of translational symmetry breaking on strange metallic systems as realised by the holographic duality⁠.

There is an increasing amount of attention on EU and its Member States contributions to implementation of two landmark agreements: the Paris Climate Agreement and the UN Agenda 2030 with Sustainable Development Goals (SDGs). Absent from the current literature is an analysis of the political effect of…

In this thesis, we explore a Hochschild homology and cohomology-like notion for logarithmic schemes.

The main object of study in this thesis is an Arakelov inequalitywhich bounds the degree of an invertible subsheaf of the direct image ofthe pluricanonical relative sheaf of a semistable family of curves.

Almost all bacteria are enveloped by a cell wall that provides cellular protection.

The Sun and all the stars in the night sky reside in the Milky Way galaxy. In the at-rest reference frame of the Galaxy, typical stars travel with velocities of about 100-200 kilometres per second.

Promotor: A. Achúcarro, Co-Promotor: G.A. Palma

The largest structures in the Universe are clusters of galaxies. Each can contain hundreds to thousands of galaxies.

This thesis is about cosmological inflation and its relation to observations.

Leiden University offers a unique range of summer courses where you can broaden or deepen your knowledge or share your expertise with fellow students. The choice of academic courses is very diverse, ranging from Law, Big Data, Languages and Linguistics to Maths and Natural Sciences, Biology, Biomedical…

This thesis describes the design, synthesis, and immunological evaluation of varying (neo)antigenic peptide conjugates containing either a TLR2 or a TLR7 agonist.

Op 8 september kwamen de studenten van de master European Law bijeen in de Lorentzzaal voor de feestelijke opening van hun programma.

Op 30 oktober jl. bezochten de studenten van de advanced master International Children’s Rights het Internationaal Strafhof te Den Haag.

The Utrecht-based VIDI project Lettercraft in Early Medieval Europe, AD 481-751 is working on a new database of Merovingian epistolary communication. We are looking for enthusiastic (R)MA students who would like to join us this Fall as research apprentices for the first phase of data entry and analysis.…

Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia

Microglia support the central and peripheral nervous system by forming the first line of defense against hazardous events. Microglia are increasingly acknowledged as critical players in neurodegenerative diseases, highlighting them as potential therapeutic targets.

A novel mathematical model describes spatial-temporal drug distribution within one or more brain units, which are cubic representations of a piece of brain tissue with brain capillaries at the edges.

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar

Promotor: Prof.dr. J.G.E.M. Fraaije, Co-promotor: A. Kros