This thesis examines enzyme domain architecture and engineering to improve the breakdown of lignocellulose and starch, abundant biopolymers crucial for sustainable biofuel and biochemical production. Carbohydrate-active enzymes (CAZymes) facilitate this degradation, but the structural complexity of…

For centuries astronomers studied the Universe by collecting light. Nowadays, we are living in times of great technological advancements, which allow us to explore our Universe in a new way - though gravitational wave radiation.

Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.

Hot astrophysical plasma is ubiquitous in the Universe, from comets in our Solar system to the largest scale structures -- the cosmic web filaments. These hot plasmas, with the temperature of a few millions of degrees, are often observed in the X-ray wavelength range.

Promotor: Prof.dr. M. de Jong

Promotor: Prof.dr. E. Smets, M. Stech

Promotor: Prof.dr. G.P. van Wezel

Promotor: W. Jiskoot, Co-promotor: H.A. Every

A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.

Large carnivores and humans, along with their livestock, have co-existed for thousands of years. However, human population growth and an increase in economic activities are modifying the landscape for large carnivores and their prey.

Despite the history of studies on methanol formation from CO2, the dominant elementary reaction steps that constitute the chemical mechanism for this catalyzed process are not determined.

The applications of studying the early development of insects range from agriculture to material science.

Promotores: F.H. van Lunteren, F.P. Israel

Humans can see the world through the eyes of other humans and imagine what they know, want, and intend. This competence is known as Theory of Mind.

Innovation plays an essential role in firms' competitiveness and long-term success. It varies from different types, ranging from run-of-the-mill innovation that brings incremental changes to existing technologies to radical innovation that breaks from existing trajectories.

The work done during this PhD research, aims to investigate the effect of tidal heatingin the observability of extra-solar satellites around exoplanets.

The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…

Nowadays, it is well known that hydrogen and helium (and small traces of lithium and beryllium) were created shortly after the Big Bang, while the heavier elements are created in the cores of stars at different evolutionary stages. When these stars explode as supernovae, they expel metals synthesised…

Promotores: H. Schiessel, G.T. Barkema

Striga hermonthica, commonly known as witchweed, infests major cereal crops in Sub-Saharan Africa causing severe yield losses and threatening the livelihood of millions of resource poor farmers.

The field of science communication is very broad. Below is a list of organisations where SCS students can fulfill internships or where alumni have found jobs.

Promotor: Prof.dr. E. Eliel, Co-Promotor: M.J.A. de Dood

Even though more than 4000 extra-solar planets are known today, only a small fraction of these has been captured in an image. To better understand the planet formation mechanisms in solar-like environments we started the Young Suns Exoplanet Survey (YSES).

Taxonomy as a science has accumulated data and knowledge for more than 250 years.

Promotor: Prof.dr. P. Stevenhagen, Co-promotor: B. de Smit

Cathodic corrosion is a relatively unknown phenomenon that can severely etch metallic electrodes at cathodic (negative) potentials.

collegereeks duurzaamheid en recht

Lipid formulations have demonstrated strong potential for nucleic acid delivery,particularly with the success of COVID-19 vaccines. Despite these advances, manyaspects of lipid formulations remain unclear.

This dissertation explores how Large Language Models (LLMs) can effectively and responsibly contribute to complex decision-making processes. By combining AI and human intelligence, Hybrid Intelligence (HI) emerges, allowing the strengths of both humans and machines to be utilized.

Fungal infections pose a significant threat to individuals with compromised immune systems and despite advancements in diagnosis and treatment, they continue to jeopardize patient’s health.

A large diversity of exoplanetary systems has been found, but it is still unclear what drives this diversity.

In this work, we attempt to answer the question:

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

Mycorrhizas are symbiotic associations between soil fungi and most plant species.

Promotor: R.D. Gill, F. Taroni

Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.

The effects of anthropogenic noise on interactions between predators and their prey are still little understood.

The Vallesian, 11.1-9 Ma, was a special time in the Vallès-Penedes basin near Barcelona, where a biodiversity hotspot existed. Europe had a subtropical climate, with rhinos, forest giraffes, lions, hyenas, flying squirrels and primates.

Heart failure is a major health care problem with high mortality.

Image segmentation is a fundamental task in computer vision, with applications ranging from medical diagnostics to archaeological research.

The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.

Promotor: G.P. van Wezel

Patterned detectors are an existing technology that can be found in almost all color cameras.

Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.

Het LAK biedt fotografie voor beginners en gevorderden aan. Tijdens de fotografiecursussen verken je de mogelijkheden van de camera die van belang zijn om de creatieve mogelijkheden van fotografie ten volle te kunnen benutten. Tijdens de gevorderden cursus ontdek en ontwikkel je een eigen handschrift. Voor…

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.

Promotores: H.A. Udo De Haes, P.M. Brakefield