Research

The Economics and Governance specialisation of the Master in Public Administration teaches you to formulate problem-solving approaches to concrete policy issues found at the intersection between economics and public administration. This specialisation is a unique joint offering of the Department of…

Overzicht van de vacatures bij de afdeling Economie.

Promotor: W. T. F. den Hollander, F. H. J. Redig

In this thesis, the focus lies on studying glucocorticoid receptor dynamics in living cells with the aim of understanding how this transcription factor finds its DNA target sites to regulate transcription.

Promotores: Prof.dr. F.S. de Boer, Prof.dr. J.J.M.M. Rutten (Radboud Universiteit Nijmegen)

Promotor: Prof.dr. M. Ubbink

This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.

Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez.

Spectroscopic studies on fluorescent single molecules in organic condensed matter does not only provide information about the molecule itself, but also its near environment. By suppression of phonon-induced broadening of spectral lines through cooling to low temperatures, small changes in the spectral…

The Copenhagen interpretation of quantum mechanics states that a measurement collapses a wavefunction onto an eigenstate of the corresponding measurement operator.

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

During my PhD research, I studied the photon statistics of light emitted by a microcavity that contains a single quantum dot (QD) on resonance.

For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.

Source: Structure , Volume 22, Issue 8, pp. 1120-1139 (2014)

Promotor: Prof.dr. D. Bouwmeester

Promotor: H.V.J. Linnartz

Hoe denken burgers over overheidsschuld? Dit project onderzoekt de politieke grondslag van overheidsschuldcrises door te kijken naar de voorkeuren van burgers voor fiscaal beleid.

Wat is het effect van maatschappelijke veranderingen, persoonlijke levensomstandigheden en migratiebeleid op iemands besluit te migreren?

Kidney transplantation is a major advance of modern medicine. This course will give you state of the art updates about what used to be an experimental, risky, and very limited treatment option more than 50 years ago and is now routinely performed in many countries worldwide.

Staatsrechtelijk analfabetisme Wie de politiek sindsdien volgt, zou misschien geneigd zijn om een stap verder te gaan en te spreken over staatsrechtelijk analfabetisme. Het lijkt er soms wel op dat vele spelers in het politieke veld zich niet meer bewust zijn van de regels van het spel en de achterliggende…

De abortuswetgeving in de Verenigde Staten staat op het punt om strenger te worden. In het radioprogramma OVT vertelt universitair docent Sara Polak waarom abortus zo’n belangrijk politiek thema is geworden.

De Afdeling Jeugdrecht van de Universiteit Leiden en Defence for Children nodigen u van harte uit voor de uitreiking van de achtste Jaap Doek Kinderrechtenscriptieprijs. Deze vindt online plaats, op donderdag 10 december van 15.30 tot 17.00 uur.

Lezing

The work described in this thesis focuses on the development of linear or cyclized peptide probes against protein N-methyltransferases to characterize their specific binding behavior, providing further binding details for inhibitory activity study.

The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.

In this top-rated course, you will learn how the European Union prepares and decides on policy, and how policy is transferred to member states and implemented by various authorities. It discusses the challenges of the European multi-level governance structure and the main causes of policy failure or…

Promotor: Prof.dr. B.R. Katzy

Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers

The increasing resistance of pathogenic bacteria to antibiotics necessitates the discovery of new medicines.

Promotor: R. Cramer

Streptomyces bacteria are a valuable source of natural products, many of which are used in the clinic or in biotechnology.

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

In this work, I explore the creation of new methods that optimize simulations of the gravitational N-body problem. Specifically, I take advantage of the recent popularity of Machine Learning methods to find tools that can suit this problem.

Striga hermonthica, commonly known as witchweed, infests major cereal crops in Sub-Saharan Africa causing severe yield losses and threatening the livelihood of millions of resource poor farmers.

Promotores: Prof.dr. S.J. Edixhoven, Prof.dr. E. Ullmo (University Paris-Sud)

The expanding population and economic activity are driving up global energy consumption. Simultaneously, there is an urgent need to transition from fossil fuels to renewable sources to mitigate the climate crisis, primarily caused by fossil fuel combustion.

Fundamental research in the ALgebra, Geometry And Number Theory

The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…

Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.

One of the key discoveries in exoplanet research over the past decade is the abundance of small planets in our Milky Way. Despite their high numbers, our understanding of their atmospheres remains limited, and it is unknown if they possess atmospheres at all.

While ecosystems have concrete benefits for human society, these benefits are typically overlooked in decision-making.

Promotor: Prof.dr. B. van de Water

This thesis describes the design, characterization and application of dextran based crosslinked network.

Stars and planets form within cold, dense clouds of gas and dust drifting through interstellar space. Although dust makes up only a small fraction of this material, it plays a key role in shaping the chemical evolution of these environments.

Promotor: T. Schmidt, Co-promotor: S. J.T. van Noort

Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.

At the largest scales, two ingredients dictate the distribution of matter in the Universe. The first is dark matter, acting as an invisible scaffolding held together by gravitational forces.

This thesis aims to investigate the effect of tripartite interaction between microbial inoculants, the plant, and herbivore insects on the rhizosphere microbiome and volatilome. We investigated the rhizosphere microbiome and volatilome of tomato plants exposed to insect herbivory and/or inoculated with…

Promotors: C.A.J. Knibbe, Anthonius de Boer, Co-promotor: M.M.J. van der Vorst