1,583 zoekresultaten voor “statistische modelling” in de Publieke website
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Data
Het gebruik van ‘Big data’ is niet meer weg te denken binnen het wetenschappelijk onderzoek. Voor dit onderzoek maken we gebruiken van diverse grote databestanden.
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Maatschappelijke adviesraad Criminologie
Hieronder informatie over deze adviesraad.
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Safe anytime-valid inference: from theory to implementation in psychiatry research
Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.
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ALL-IN meta-analysis
Science is typically a patchwork of research contributions without much coordination. Especially in clinical trials, the follow-up studies that we do fail to be the most promising.
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Psychology
Leer meer over de Engelstalige bachelor Psychology aan de Universiteit Leiden. Bekijk de voorlichtingsvideo en ontdek of deze veelzijdige studie bij je past!
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Psychologie
Psychologie studeren in Leiden? Alles komt aan bod in deze video: van toelating tot vervolgstappen en meer.
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Studying the Benefits of Using UML on Software Maintenance: an Evidence-Based Approach.
Including modelling as part of software development appears to have various benefits.
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The endocannabinoid system in zebrafish larvae
In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.
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Frank den Hollander koninklijk onderscheiden
Frank den Hollander, hoogleraar Kansrekening, is op 15 december onderscheiden als Ridder in de Orde van de Nederlandse Leeuw.
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Developing systems for high-throughput screening of infectious diseases using zebrafish
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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De arrogantie van de statisticus
Van ongeveer 30% van de medische studies blijkt dat het beweerde effect achteraf geen stand houdt: ‘dit geneesmiddel werkt tóch niet’, stelde Peter Grünwald op 6 november in zijn oratie. Dit is schrikbarend meer dan op grond van de statistiek verwacht mag worden.
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Data-driven donation strategies: understanding and predicting blood donor deferral
The research in this dissertation aims to optimise blood donation processes in the framework of the Dutch national blood bank Sanquin. The primary health risk for blood donors is iron deficiency, which is evaluated based on donors' hemoglobin and ferritin levels.
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Boosting the host immune system to fight tuberculosis
New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.
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Towards predictive cardiovascular safety: a systems pharmacology approach
Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski
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Random walks and the contact process
Promotores: W. Th. F. den Hollander, M.O. Heydenreich
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Into the Darkness: Forging a Stable Path Through the Gravitational Landscape
In this thesis we study the landscape of gravitational models which modify GR by introducing an additional scalar degree of freedom (d.o.f.) to source Cosmic Acceleration.
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De perspectieven van professionele gebruikers op metaforen in machinevertaling
Dit onderzoek gaat over hoe literaire vertalers en journalisten reageren op en omgaan met machinevertaalde metaforen, en wat de gevolgen daarvan zijn voor de beroepspraktijk.
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Thermostable Nanodiscs for the development of novel biopharmaceuticals
Nanodiscs are small, disc-shaped structures designed to mimic biological cell membranes, composed of a lipid bilayer stabilized by scaffold proteins. Membrane proteins play crucial roles in essential processes such as nutrient and waste transport, molecular recognition, and cell signalling, making them…
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Novel pharmacometric techniques to quantify the pharmacodynamics of analgesics
The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.
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Surf Innovation Challenge Awards voor Shabaz Sultan en Simon Portegies Zwart
Shabaz Sultan en Simon Portegies Zwart, met de hulp van Vincent Icke, hebben één van de tien Surf Innovation Challenge Awards gewonnen voor hun onderzoek naar 'Interactive high-performance laboratory for Chaos'. De winnaars hebben een geldprijs van 10.000 euro ontvangen en krijgen 6 maanden (tot 1 juni…
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Mosselen organiseren zich als moleculen in materiaal
Mosselen in mosselbedden vormen een patroon dat lijkt op de organisatie van moleculen en atomen in materialen als brons, staal of rubber. Dit gedrag kan dan ook worden beschreven met hetzelfde wiskundige model.
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Dynamical Gibbs-non-Gibbs transitions and Brownian percolation
Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez.
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Samenwerkend leren bij lerarenopeldingen
Het ontwikkelen, gebruiken en evalueren van groepsopdrachten in het hoger onderwijs.
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Dynamic real-time substrate feed optimization of anaerobic co-digestion plants
Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)
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Methoden van contractsuitleg
Op 20 juni verdedigde Anne Hendrikx het proefschrift 'Methoden van contractsuitleg: een model voor de uitleg van een overeenkomst'. Het promotieonderzoek is begeleid door Henk Snijders.
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A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
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Foam rheology near the jamming transition
Promotor: Prof.dr. M.L. van Heck, Co-Promotor: B.P. Tighe
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Probing new physics in the laboratory and in space
The Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles.
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Phenotypic screening with 3D cell-based assays
Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.
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Diagnostics for mechanical heating in star-forming galaxies
Promotor: F.P. Israel, Co-Promoter: R. Meijerink
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Playing dice with the Universe
The ultimate goal of cosmologists is to find a cosmological model able to explain the current observational data.
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GLOBOX
GLOBOX is a spatially differentiated multimedia fate, exposure and effect model. It is used for the calculation of spatially differentiated LCA characterisation factors on a global scale.
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Tomer FishmanFaculteit der Wiskunde en Natuurwetenschappen
t.fishman@cml.leidenuniv.nl | 071 5272727
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Van Tekst naar Kennis: Taalmodellen voor Extractie van Kennisgrafen en Ontologieën
Dit promotieonderzoek onderzoekt hoe taalmodellen kunnen worden ingezet om gestructureerde kennis uit tekst te extraheren op een manier die nauwkeurig, robuust en toepasbaar is in praktijksituaties.
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NWO Open Competitie subsidie voor Leidse onderzoekers
Twee onderzoeksprojecten van de Universiteit Leiden ontvangen subsidie vanuit de NWO Open Competitie ENW-M. Hiermee wordt vernieuwend, fundamenteel onderzoek van hoge kwaliteit binnen het domein Exacte en Natuurwetenschappen gefinancierd.
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Towards circular and energy-efficient management of building stock
Material circularity and energy efficiency are highly relevant and intertwined issues for the transition towards a carbon-neutral and circular built environment. In the Netherlands, the building sector has been rendered a priority towards a circular and low-carbon society.
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Vier Vici's voor Leidse onderzoekers
Leiden scoort goed bij de Vici's. Onder de 31 Vici-winnaars wier namen NWO begin februari bekendmaakte, zijn vier Leidse wetenschappers. De winnaars zijn: gezinspedagoog Marian Bakermans-Kranenburg, informaticus Peter Grünwald, sterrenkundige Harold Linnartz en hoogleraar Boeddhisme Jonathan Silk.
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Yingjie FanFaculteit der Wiskunde en Natuurwetenschappen
y.fan@liacs.leidenuniv.nl | 071 5274799
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Trustworthy anomaly detection for smart manufacturing
This dissertation explores how we can make anomaly detection—identifying unusual or faulty behavior in complex systems—more trustworthy and effective, with a focus on smart manufacturing.
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Vervolgopleidingen
LUC alumni hebben een internationaal erkend Bachelor Honours-diploma (BA/BSc) waar ze hun pad na LUC mee voortzetten. Meer dan 90% van onze alumni doet een masterprogramma na het afstuderen aan LUC. Hun kennis en doorzettingsvermogen is duidelijk zichtbaar. Velen starten hun studies in competetive programma's…
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Nonparametric Bayesian Methods in Robotic Vision
In this dissertation non-parametric Bayesian methods are used in the application of robotic vision.
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Massively collaborative machine learning
Promotor: J. N. Kok, Co-promotor: A. J. Knobbe
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Sterile neutrinos in the early Universe
Promotor: A. Achúcarro, Co-promotor: A. Boyarsky
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Development of a healthy and diseased artery-on-a-chip
Cardiovascular diseases are a leading cause of death worldwide, and better models are urgently needed for disease progression studies and drug development.
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Dormancy in stochastic interacting systems
Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.
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Big simulations for big problems
In this thesis we investigate cosmology and the large scale structure of the Universe using cosmological simulations.
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Coiled-coils on lipid membranes: a new perspective on membrane fusion
Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros
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Developing metabolomics for a systems biology approach to understand Parkinson's disease
Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…
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Computational speedups and learning separations in quantum machine learning
This thesis investigates the contribution of quantum computers to machine learning, a field called Quantum Machine Learning. Quantum Machine Learning promises innovative perspectives and methods for solving complex problems in machine learning, leveraging the unique capabilities of quantum computers…