755 zoekresultaten voor “global gene regulation” in de Publieke website
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General plant strategies and functions in wetlands: Global trait-based analyses
Wetland plants are distinguished from plants of other terrestrial ecosystems by their adaptations to specific habitat stresses, including waterlogged and flooding and the subsequent abundance of phytotoxic compounds.
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The Ecology and Evolution of Microbial Warfare in Streptomyces
The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.
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XR (Extended Reality) to learn global challenges
Ontwikkeling van effectieve VR-training voor internationaal recht van gewapende conflicten (ILAC)
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Assessing global regionalized impacts of eutrophication on freshwater fish biodiversity
Freshwater biodiversity has been threatened by eutrophication due to excessive nutrients in the environment. Releasing the freshwater species from such pressures requires efforts from industry and manufacturers to avoid emissions to vulnerable and high-risk regions.
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Precision modeling of breast cancer in the CRISPR era
The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.
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Disentangling drought-responsive traits with focus on Arabidopsis
In recent decades, climate change has led to more frequent and severe drought events, causing serious consequences such as increased forest mortality and significant crop yield losses. Understanding how drought affects plants, especially economically important herbaceous species, is crucial for predicting…
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Political Muslims: Understanding Youth Resistance in a Global Context
An interdisciplinary collection of the best international scholarship on Muslim youth.
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Strategies for the improvement of genome editing in Arabidopsis thaliana
Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.
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Conference on Private law and market regulation georganiseerd door de onderzoeksgroep Coherent Privaatrecht
Op vrijdag 2 december 2016 heeft een internationale onderzoeksconferentie plaatsgevonden in Leiden. Deze was georganiseerd door de onderzoeksgroep van Coherent Privaatrecht. De conferentie droeg de titel “Private law and market regulation – interaction, interference or inconsistency?”. Het centrale…
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The role of the tumor suppressor Lkb1 in energy homeostasis
The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.
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Structural changes in single chromatin fibers induced by tension and torsion
Promotor: T. Schmidt, Co-promotor: S. J.T. van Noort
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The Invisible History of the United Nations and the Global South - INVISIHIST
The main aim of this project is to reveal and unravel the invisible histories of the UN, transcending the dominant Western perspective to recover the historical agency of Global South actors. The research will investigate how the UN has both facilitated and limited their role in shaping global order…
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Liberal Arts and Sciences: Global Challenges (BA/BSc) - Leiden University College
Bij Leiden University College The Hague staan Global Challenges centraal. Global Challenges zijn de grote, maatschappelijke uitdagingen van de 21ste eeuw waar we gezamenlijk een oplossing voor moeten vinden, zoals klimaatverandering, armoede, ongelijkheid, vrede en recht. Onze opleiding is opgesplitst…
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Multi-Objective Bayesian Global Optimization for Continuous Problems and Applications
A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.
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Exploring the chemical space of natural products from Streptomyces using multi-omics approaches
The increasing resistance of pathogenic bacteria to antibiotics necessitates the discovery of new medicines.
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Upcoming Research Conference on Private law and market regulation in Leiden
Op vrijdag 2 december vindt in Leiden een internationale, multidisciplinaire conferentie plaats gecentreerd rond onderzoek over burgerlijk recht en marktregulering. De conferentie draagt de titel “Private law and market regulation – interaction, interference or inconsistency?” en wordt georganiseerd…
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Nadia Garnefski
Faculteit der Sociale Wetenschappen
garnefski@fsw.leidenuniv.nl | +31 71 527 3774
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Winifred Gebhardt
Faculteit der Sociale Wetenschappen
gebhardt@fsw.leidenuniv.nl | +31 71 527 4084
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Modulating the behaviour of pancreatic tumour cells
Promotores: Prof.dr. M.K. Richardson, Prof.dr. H.P. Spaink. Co-promotor: C.P. Bagowski
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Discovery of novel Antibiotics from Actinomycetes by Integrated Metabolomics & Genomics Approaches
Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi
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UN 2.0: Ten Innovations for Global Governance 75 Years beyond San Francisco
Dr. Joris Larik, universitair docent vergelijkend, EU- en internationaal recht bij LUC The Hague, is coauteur van het rapport 'UN 2.0: Ten Innovations for Global Governance 75 Years beyond San Francisco'.
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Trans-kingdom DNA transfer
The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.
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A New Model of Global Governance in International Tax Law Making (GLOBTAXGOV)
Dr. Irma Mosquera Valderrama onderzoekt in haar ERC-project de rol van de OESO (Organisatie voor Economische Samenwerking en Ontwikkeling) en de EU bij de totstandkoming van internationale fiscale wetgeving en streeft ernaar voorwaarden te scheppen waaronder zowel ontwikkelde landen als ontwikkelingslanden…
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Nucleosome stacking in chromatin fibers probed with single-molecule force- and torque-spectroscopy
In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.
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Do companies walk the talk? Commitments and actions in global supply chain labor standards
Dit artikel onderzoekt de auteurs de inspanningen om minimale arbeidsnormen in wereldwijde toeleveringsketens te implementeren vanuit het perspectief van maatschappelijk verantwoord ondernemen.
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Phenotypic plasticity and genetic adaptation of plant functional traits on global scales
In light of climate change, it is crucial to determine whether plant species can adapt to future climates to avoid extinction. Plants adapt to various conditions by altering their functional traits, such as leaf size or photosynthetic rate. Some traits appear linked and vary together between species,…
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Histone-DNA assemblies in archaea. Shaping the genome on the edge of life
All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).
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Addressing climate change with behavioural science: A global intervention tournament in 63 countries
Dit artikel beschrijft het ontstaan van een app die kan helpen om het klimaatbewustzijn en de actie wereldwijd te vergroten.
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Going global to local: achieving agri-food sustainability from a spatially explicit input-output analysis perspective
The global agri-food system plays a critical role in food security and environmental issues.
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Weighting factors for LCA - A new set from a global survey
De auteurs presenteren een benadering voor het achterhalen van de voorkeuren van de bevolking voor gebruik in de optionele wegingstap in de Levenscyclusanalyse (LCA).
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Global metabolomics and lipidomics approaches to probe virus-host interactions
The outbreaks of AIDS and COVID-19 showed clearly how infectious viruses can influence people’s lives. Investigating the changes in the host metabolism may provide a paradigm shift to consider immune-metabolic interactions as therapeutic targets.
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Global fitness maximising approaches to evaluate the trade-offs involved in the evergreen and deciduous conundrum
Which traits and/or trade-offs determine benefits of being deciduous or evergreen?
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Building Northern Public Support to Finance Climate Policies in the Global South
Als onderdeel van het Akkoord van Parijs kwamen landen over de hele wereld overeen om ontwikkelingslanden te steunen bij het investeren in klimaatmitigatie en -adaptatie via een Green Climate Fund. Ontwikkelde landen zijn er echter niet in geslaagd om de financieringsverplichtingen voor het Green Climate…
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Multi-omics studies of the control of growth and antibiotic production of Streptomyces
Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).
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Close-out Netting: A comparative study of English, French and US laws in a global perspective
Op 1 december 2020 verdedigde Bernadette Muscat haar proefschrift 'Insolvency Close-out Netting: A comparative study of English, French and US laws in a global perspective'. Het promotieonderzoek is begeleid door promotoren prof.mr.drs. M. Haentjens en prof.mr. B. Wessels.
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Medieval and Early Modern History: Europe in its Global Context
Het Leiden Instituut voor Geschiedenis heeft een uitzonderlijk sterke expertise in premoderne Europese geschiedenis in haar mondiale context, met specialisten wier interesses vrijwel het hele continent bestrijken. We hebben een sterke staat van dienst in het leiden van grotere onderzoeksteams en werken…
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Cities, migration and global interdependence 1350-2000
The research programme Cities, Migration and Global Interdependence 1350-2000 (CMGI) focuses on urbanisation, migration, and economic development in a comparative and global context.
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Nieuwe decaan Faculteit Governance and Global Affairs
Het College van Bestuur heeft besloten prof. dr. Kutsal Yesilkagit met ingang van 1 januari 2016 voor een periode van 3 jaar te benoemen tot decaan van de Faculteit Governance and Global Affairs.
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in international organizations: How UN peace operations respond to global normative change and shifting power distributions
Tom Buitelaar dat de micro-niveau discours van internationale organisaties zich imperfect aanpast aan macro-niveau veranderingen, waarbij aanpassing aan macrodruk wordt afgewogen tegen de toewijding aan persistente organisatorische waarden.
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The Local Impact of a Global Court: Assessing the Impact of the International Criminal Court in Situation Countries
Op 9 januari 2019 verdedigde Marieke Wierda haar proefschrift 'The Local Impact of a Global Court: Assessing the Impact of the International Criminal Court in Situation Countries'. Het promotieonderzoek is begeleid door promotoren prof. dr. C. Stahn en prof.dr. L.J. van den Herik.
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Aquatic eDNA: Beyond Species Presence
As a non-invasive genetic method, eDNA based approaches have become an important component of ecologists' and environmental managers' toolkits for biomonitoring in conservation and an increasingly important source of ecological knowledge.
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Key innate immune components controlling intracellular infection
Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer
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Directeur UN Global Pulse bezoekt Faculteit
Robert Kirkpatrick, directeur van UN Global Pulse, bezocht de Faculteit der Wiskunde en Natuurwetenschappen op dinsdag 27 oktober 2015.
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Ebbe Rogge
Faculteit Rechtsgeleerdheid
e.rogge@law.leidenuniv.nl | +31 71 527 2727
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MIRD students explore global diplomacy in Brussels
Brussels, the heart of European diplomacy, offered MSc International Relations and Diplomacy (MIRD) students a two-day opportunity to explore NATO and the European External Action Service (EEAS), gaining valuable insights into their roles in shaping EU foreign policy and global security.
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Molecular engineering of plant development using Agrobacterium-mediated protein translocation
Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa
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Faculteit Campus Den Haag wordt Faculteit Governance and Global Affairs
De Faculteit Campus Den Haag krijgt per 1 januari 2016 een nieuwe naam: Faculteit Governance and Global Affairs. Deze nieuwe naam is een logische samenstelling van de componenten van deze faculteit.
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European Union Regulation on Insolvency Proceedings: An Introductory Analysis (Vierde Editie)
Dit boek, geschreven door prof. mr. Bob Wessels (em.) en Ilya Kokorin LLM, , beschrijft en analyseert de Europese insolventieverordening (herschikt) ('EIR 2017’) die inwerking is getreden in juni 2017.
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Chemical genetic approaches for target validation
Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.
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Functions of leptin in tuberculosis and diabetes: multi-omics studies across species
In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.