This ecological community has long been known to affect host biology, and their diverse roles have been further clarified in recent years following numerous studies of animal:microbiota interactions in diverse systems.

This thesis manuscript explores the use of video games as tools for conceptual exploration and academic research.

This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;

Taal als sleutel tot het begrijpen van de mens.

Galaxies in the local Universe fall into two main categories of spirals and ellipticals. In this Thesis, we explore the structural evolution of galaxies into this bimodal distribution.

This thesis describes a study from both a theoreticaL and an experimental point of view.

Glucocorticoids are potent anti-inflammatory drugs widely used clinically to treat various inflammatory and immune conditions. However, two main clinical problems limit their use. GCs trigger severe side effects and they induce acquired glucocorticoid resistance, especially during chronic systemic treatment…

This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.

Planets are formed in disks of gas and dust around young stars.

Onderwijs over quantum is ontzettend belangrijk. Daarom ontwikkelt Quantum Leiden onderwijs en voorlichting over de quantumtechnologie, op alle niveaus, van middelbare school tot Masters-studie. Zo leiden we de onderzoekers van de toekomst op, en bereiden we de jeugd voor op een quantumtoekomst.

Promotor: E. Gittenberger, Co-promotor: B.W. Hoeksema

In het onderzoek wordt de situatie voor bescherming van persoonsgegevens vergeleken in acht Europese landen: Frankrijk, Duitsland, het Verenigd Koninkrijk, Ierland, Roemenië, Italië, Zweden en Nederland. De vergelijking tussen de landen is gericht op het overheidsbeleid voor bescherming van persoonsgegevens,…

Promotor: Prof.dr. W.J.G.M. Peijnenburg

Dit project gaat over een grafaltaar met een Latijnse inscriptie voor Q. Petronius Turnus. Het werd gevonden in Rome en gedateerd op de eerste eeuw na Christus. Het werd onderdeel van de collectie van Baron Van Westreenen en bevindt zich nu in Museum Het Huis van het boek te Den Haag.

Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier

Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown

Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…

Promotores: Prof.dr. E.F. van Dishoeck, Prof.dr. C.P. Dullemond

Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov

In this thesis, we study different curved single crystals because of the diversity of surface structures across their curvature.

Wil je deelnemen aan ons onderzoek in Psychologielab op Wielen? Momenteel hebben we twee experimenten in de bus. Natuurlijk zorgen we voor de bescherming van je gegevens en privacy. Doe mee met onze experimenten en meld je aan.

This thesis examines the link between simple molecules and the underlying structure and chemistry within protoplanetary disks - the birthplaces of planets.

This thesis involves three topics: benchmarking discrete optimization algorithms, empirical analyses of evolutionary computation, and automatic algorithm configuration.

This thesis focuses on enhancing predictions of central nervous system drug exposure using the LeiCNS-PK3.0, a physiologically based pharmacokinetic model.

Microbiome composition of the spermosphere and the rhizosphere of wild and modern bean accessions grown in an agricultural and a native soil from Colombia was characterized by metagenomics and cultivation-dependent approaches.

Angst hangt samen met emotie regulatie. Negatieve emoties trekken onze aandacht. Uit onderzoek weten we dat mensen die angstig zijn, sneller letten op een boos gezicht dan op een neutraal gezicht. Vervolgens kijken ze ook sneller weg van een boos gezicht. Over jonge kinderen is minder bekend en over…

De Grachtwacht doet onderzoek naar stadsnatuur en de impact van plastic op de natuur. Met onze clean-ups verzamelen we niet alleen afval, maar ook data. Zo proberen we de bron van het afval te achterhalen en de kraan aan wal dicht te draaien. Zo komt er structureel minder plastic in de gracht!

Acute cardiovascular syndromes, including myocardial infarction or stroke, are the principal cause of death in the Western society. The main underlying pathology of cardiovascular diseases is atherosclerosis, which is caused by the accumulation of lipids and inflammatory cells in the vessel wall, in…

Sewer pipes are an essential infrastructure in modern society and their proper operation is important for public health. To keep sewer pipes operational as much as possible, periodical inspections for defects are performed.

In most applications, electrocatalysts exhibit a large surface area to volume ratio, for example using nanoparticles.

The physical origin of the dozens of stellar-mass binaries, the mergers of which have been detected by the LIGO-Virgo-KAGRA collaboration via gravitational waves, is still unknown.

Recentelijk is een Special Issue van de European Journal of Criminology verschenen, die is samengesteld door Marieke Liem, Universitair Docent Criminologie bij het Instituut voor Strafrecht & Criminologie, en William Pridemore.

LLInC ondersteunt innovatief en hoogwaardig onderwijs, binnen de Universiteit Leiden en in samenwerking met onderwijs- en maatschappelijke organisaties.

The invention of neural networks marks a critical milestone in the pursuit of true artificial intelligence. Despite their impressive performance on various tasks, these networks face limitations in learning efficiently as they are often trained from scratch.

This thesis investigates how quantum, quantum-inspired, and hybrid quantum-classical computation can enhance key points of the automated machine learning (AutoML) pipeline under the constraints of noisy intermediate-scale quantum (NISQ) devices.

Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.

Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.

Mycoheterotrophy is a particular mode of life in which plants obtain carbohydrates from their associated fungal partners, instead of by using photosynthesis.

Galaxy intrinsic alignments induce a major astrophysical contamination to weak gravitational lensing measurements and need to be modelled and mitigated when extracting cosmological information from such measurements.

It has now been well established that shocks and turbulent motions in the intra-cluster medium (ICM) generated through cluster mergers can produce large-scale synchrotron emission.

In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.

Op welke manieren heeft cybersecurity invloed op de relatie tussen overheden en burgers?

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. M. van der Zee

Promotor: Prof.dr. G.R. de Snoo

De Faculteit Geesteswetenschappen publiceert jaarlijks een D&I kalender. Deze kalender dient als instrument om bewustzijn en begrip te creëren voor belangrijke religieuze feestdagen en andere vieringen van de diverse groepen binnen onze academische gemeenschap.

At the largest scales, two ingredients dictate the distribution of matter in the Universe. The first is dark matter, acting as an invisible scaffolding held together by gravitational forces.

Promotor: Prof.dr. E. Deprettere