1,525 zoekresultaten voor “aanraking op based van afbeeldingen” in de Publieke website
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Single-electrolyte isotachophoresis: on-chip analyte focusing and separation
Promotor: Thomas Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto
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Meng Lim.li@cml.leidenuniv.nl | 071 5272727
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Roy Remmer.p.remme@cml.leidenuniv.nl | 071 5275610
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Haye Geukesh.h.geukes@cml.leidenuniv.nl | 071 5272727
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Qinyu Chenq.chen@liacs.leidenuniv.nl | 071 5272727
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Amelie Müllera.muller@cml.leidenuniv.nl | 071 5272727
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Marina Gorostiola Gonzálezm.gorostiola.gonzalez@lacdr.leidenuniv.nl | 071 5272727
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Ming Frickem.m.fricke@cml.leidenuniv.nl | 071 5272727
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Hebben banken mensenrechten?
Op dinsdag 1 oktober 2019 ontving het Hazelhoff Centre for Financial Law voor de negentiende Hazelhoff Guest Lecture Paul Sharma, managing director bij Alvarez & Marsal en co-head van praktijkgroep European Financial Industry Regulatory Advisory Services.
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Management of Small-Scale Fisheries at the Elephant Marsh in Malawi
Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…
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Microstructural and Metabolic Alterations in the Zebrafish Brain Induced by Toll-Like Receptor 2 Deficiency
Advanced UHF MRI techniques provide powerful tools for studying the zebrafish brain, an emerging model in neurological research. In this work, various MRI and localized MRS methods are optimized and employed for UHF strength for studying the zebrafish brain.
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Getting personal: Advancing personalized oncology through computational analysis of membrane proteins
Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.
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A macro level assessment of material circularity
A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.
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Broadening Youth Participation in STEM Learning
How can we broaden youth participation in STEM Learning
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Efficient tuning of automated machine learning pipelines
Automated Machine Learning (AutoML) is widely used to automatically build a suitable practical Machine Learning (ML) model for an arbitrary real-world problem, reducing the effort of practitioners in the ML development cycle for real-world applications. Optimization is a key part of a typical AutoML…
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Evolutionary molecular dynamics
This thesis introduces the concept of
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Biological model representation and analysis
Promotor: Prof.dr. J.N. Kok, Co-promotor: F.J. Verbeek
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Innovative sample preparation and handling strategies for automated and high-throughput metabolomics
Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…
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Identification of novel targets in prostate cancer progression
Promotor: B. van de Water, Co-promotor: E.H.J. Danen
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Application of zebrafish and murine models in lipoprotein metabolism and atherosclerosis research
Cardiovascular diseases are still a major concern for the global health.
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Healthcare Information System Engineering: AI Technologies and Open Source Approaches
Healthcare Information Systems (HIS) are essential for modern healthcare delivery, yet their development faces significant challenges including heterogeneous data formats, regulatory compliance, and the growing demand for AI-driven decision support.
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Data-Driven Machine Learning and Optimization Pipelines for Real- World Applications
Machine Learning is becoming a more and more substantial technology for industry.
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Internationalisering
De Universiteit Leiden wil haar studenten toerusten voor de wereld van morgen. In ons onderwijs stimuleren we internationale kennis, mondiaal bewustzijn en interculturele vaardigheden.
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Waarom Universiteit Leiden?
Je kiest voor de studie Bio-Farmaceutische Wetenschappen wanneer je sterk geïnteresseerd bent in de ontwikkeling van en het onderzoek naar de werking van geneesmiddelen.
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Lil'Scientist
Kinderen zijn van nature kleine wetenschappers. De beste manier om ze kennis te laten maken met wetenschap is door ze aan het werk te zetten en ze daadwerkelijk wetenschappelijk onderzoek te laten doen.
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Generalized Strictly Periodic Scheduling Analysis, Resource Optimization, and Implementation of Adaptive Streaming Applications
This thesis focuses on addressing four research problems in designing embedded streaming systems.
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Internationale consortia: de toekomst voor de wetenschap?
Internationale wetenschappelijke consortia zijn steeds belangrijker binnen de wetenschap. Ze staan tegenwoordig vaak centraal bij de aanpak van mondiale vraagstukken op het gebied van gezondheid, milieu en schone energie. Ze kennen echter ook unieke uitdagingen. Om die in kaart te brengen, ontving hoogleraar…
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Wie is er aan de beurt? De rol van spraakmelodie bij beurtwisselingen in het Nederlands
Als mensen met elkaar praten wisselen sprekers elkaar soepel af, met gemiddeld zeer korte tussenliggende pauzes. Gesprekspartners moeten daarom steeds vooruit plannen wat ze willen zeggen en wanneer ze de beurt kunnen overnemen. Spraakmelodie speelt hier hoogstwaarschijnlijk een rol bij, maar onduidelijk…
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ERC Synergy-beurs voor het ontcijferen van suiker-barcodes voor gezondheid en duurzaamheid
Hermen Overkleeft en zijn collega’s Gideon Davies (Universiteit van York) en Carme Rovira (Universiteit van Barcelona) ontvangen een ERC Synergy Grant ter waarde van 9,1 miljoen euro. Samen zullen zij het Carbocentre Synergy-team vormen voor onderzoek naar enzymen die werken op glycans: complexe koolhydraten.…
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A chemical biology approach for targeting of ligand-drug conjugates
Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot
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Tijdreizen met Clusius
Vijfhonderd jaar Charles de l'Écluse
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Tijdreizen met Clusius
Vijfhonderd jaar Charles de l'Écluse
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Robust rules for prediction and description.
In this work, we attempt to answer the question:
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The quantification of growth hormone secretion : application of model-informed drug development in acromegaly
Growth hormone profiles are pulsatile and highly variable between individuals, limiting the implementation of mathemathical models to quantify an individual's secretion.
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Discovery of novel inhibitors to investigate diacylglycerol lipases and α/β hydrolase domain 16A
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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Business incubators: the impact of their support
A New Technology-Based Firm (NTBF) is a significant enabler of job creation and a driver of the economy through stimulating innovation.
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Iron complexes as electrocatalysts for the water oxidation reaction
In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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Innovative strategies to clinically characterize the human tear proteome
Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.
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Understanding the value of social media metrics for research evaluation
The availability of indicators based on social media has opened the possibility to track the online interactions between social media users and scholarly entities.
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Analysis of sub-visible particles in complex injectable formulations
Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik
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The tension between nature conservation and economic valuation of ecosystem services
Promotores: G.R. de Snoo, W.T. de Groot, Co-promotor: C.J.M. Musters
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Understanding functional dynamics and conformational stability of beta-glycosidases
Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.
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Reconstruction Methods for Combined HAADF-STEM and EDS Tomography
The research in this thesis is focused on tomographic reconstruction based on two imaging modalities in electron microscopy.
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An Algebra for Interaction of Cyber-Physical Components
Modeling and analysis of cyber-physical systems are still challenging. One reason is that cyber-physical systems involve many different parts (cyber or physical), of different nature (discrete or continuous), and in constant interaction via sensing and actuating.
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Graphene at fluidic interfaces
In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…
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Mechanistic studies of the water oxidation reaction with molecular iron catalysts
In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.
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Omics data integration with genome-scale modelling of dopaminergic neuronal metabolism
Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.
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Musems, Collections and Society | Yearbook 2021
In this Yearbook you will find some fascinating examples of what was done in 2021, not only by ourselves, but also by our international colleagues.
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Quantitative pharmacology of antimicrobials
Antimicrobial drugs constitute a fundamental part of modern medicine. The global rise in antimicrobial resistance poses a major threat to global health.