50 zoekresultaten voor “organ transplantation” in de Publieke website
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Online Course Clinical Kidney, Pancreas and Islet Transplantation
Kidney transplantation is a major advance of modern medicine. This course will give you state of the art updates about what used to be an experimental, risky, and very limited treatment option more than 50 years ago and is now routinely performed in many countries worldwide.
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Individualized dosing of serotherapy in allogeneic hematopoietic cell transplantation - a delicate balance
Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius
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Gene networks-based mechanistic assessment of drug-induced organ toxicity: a focus on liver and kidney
Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.
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Bioengineering and biophysics of viral hemorrhagic fever
Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…
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Innovative strategies to clinically characterize the human tear proteome
Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.
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Preclinical validation of putative targets in cardiovascular and metabolic disease
Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.
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Targeting macrophages in renal transplantation
Promotie
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Mitochondria in chemical-induced toxicity
Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…
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Patient-relevant outcomes after kidney transplantation
Promotie
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Targeting Inter-Organ Cross-Talk in Cardiometabolic Diseases
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pharmacometrics to optimize immunosuppressive therapy in kidney transplantation
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Improving survival prediction models for liver transplantation candidates
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pharmacokinetics and dynamics in pediatric allogeneic stem cell transplantation
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Metabolomic characteristics of Catharanthus roseus plants in time and space
Promotor: R. Verpoorte, Co-promotores: Y.H.Choi, N.R. Mustafa
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Online Course Anatomy of the Abdomen and the Pelvis: a journey from basic to clinic
In this course, you will explore the organs involved in our food digestion and discover the common causes of abdominal and pelvic pain. The latest graphics and animations will give you new insights and understandings of this part of the body.
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Development of an Adverse Outcome Pathway (AOP) for metallic nanoparticles
What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?
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Development of an in vitro vascular network using zebrafish embryonic cells
One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.
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HLA epitopes in kidney transplantation: from basic science to clinical application
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Studying the short-term complications of kidney transplantation: from bed to bench.
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Fecal microbiota transplantation and dietary interventions in Inflammatory Bowel Disease; efficacy and challenges for the future
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Marlies Reinders
Integratie van MOOC in campus
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Modulation of leukocyte homeostasis in atherosclerosis
Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel
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Development of hyaluronan-based dissolving microneedle arrays for dermal vaccination
Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.
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Uncovering vulnerabilities in triple-negative breast cancer
Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.
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Multi Modal Representation Learning and Cross-Modal Semantic Matching
Humans perceive the real world through their sensory organs: vision, taste, hearing, smell, and touch. In terms of information, we consider these different modesalso referred to as different channels of information or modals.
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Microneedle-mediated vaccine delivery
Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot
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Functions of P38 and ERK kinases in zebrafish early development
Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar
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Towards automated identification of metabolites using mass spectral trees
Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers
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Developmental effects of polystyrene nanoparticles in the chicken embryo
There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.
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difficile and multidrug-resistant bacteria, and faecal microbiota transplantation as an intervention strategy
Promotie
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Gratis grootschalig online onderwijs: MOOCs
De gratis online academische cursussen van de universiteit zijn voor iedereen over de hele wereld te volgen.
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challenge of quality assessment and regional perfusion to increase donor organ utilisation
Promotie
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Systematics, Epidermal defense and Bioprospecting of Wild Orchids
This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.
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Evolution and development of flowers, fruits and inflorescences of Phalaenopsis and other orchid species
The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.
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The evolution of shell form in tropical terrestrial microsnails
Promotor: Prof.dr. M. Schilthuizen
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Novel role of the AT-HOOK MOTIF NUCLEAR LOCALIZED 15 gene in Arabidopsis meristem activity and longevity
Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.
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Arabidopsis AGC3 kinases and PIN plasma membrane abundance
The plant hormone auxin plays a central role in the growth and development of plants. Auxin acts in a concentration dependent manner and polar cell-to-cell transport of this hormone determines its distribution in the tissues of plants. This polar auxin transport is mediated by several families of auxin…
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Evolution and development of orchid flowers and fruits
To gain more insight into the evolutionary development of orchid flowers and fruits, the orchid species Erycina pusilla was studied. The evolutionary origin of the median petaloid sepal, the callus on the labellum, and the stelidia was studied.
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Value-Based Healthcare in Long-term Follow-up after Pediatric Stem Cell Transplantation for Nonmalignant Diseases
Promotie
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Leids Universitair Medisch Centrum
Het LUMC staat voor de verbetering van de gezondheidszorg en de gezondheid van mensen. Deze missie brengen de medewerkers van het LUMC dagelijks in de praktijk met toonaangevend onderzoek, vernieuwend onderwijs en optimale, innovatieve zorg.
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Jantine Brussee tweede in PhD-competitie
Farmacologe Jantine Brussee won op 4 oktober de tweede prijs in de Figon-Pfizer PHD Student competition tijdens de DUtch Medicine Days in Ede.
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Alumni
Sinds 2009 behaalden 84 kandidaten hun doctoraat in Creative en Performing Arts. Op deze pagina een overzicht van ACPA's alumni.
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MOOCs zijn meer dan online onderwijs
De Universiteit Leiden biedt inmiddels bijna twintig Massive Online Open Courses (MOOCs) aan. Het maken en doceren in zo’n online cursus levert meer op dan enthousiaste cursisten, vertellen MOOC-docenten Marlies Reinders en Edwin Bakker. ‘Je brengt een wereldwijde community bijeen.’
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Nederland wordt wereldspeler met ‘organ-on-chip’ technologie
Organ-on-chip technologie wordt ingezet bij geneesmiddelenonderzoek en op maat gemaakte behandelingen van patiënten. Kennisinstellingen en industrie verenigen hun krachten binnen het ‘Institute for human Organ and Disease Model Technologies’ (hDMT) dat 18 mei officieel van start is gegaan. Door faciliteiten,…
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Postdoc Computational Modeling for Drug Safety Prediction
Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)
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MOOC ‘Miracles of Language’: divers en interactief
Bent u geïnteresseerd in taal? In de Leiden MOOC ‘Miracles of Language’, laat prof.dr. Marc van Oostendorp cursisten kennis maken met de veelzijdige studie van de talen van de wereld. Analyseer uw moedertaal en leer hoe uw taal lijkt op en verschilt van veel andere talen.
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Ziektes beter begrijpen dankzij organ-on-a-chip
Voor het doen van medisch onderzoek bouwen onderzoekers vaak weefsel na in het laboratorium. Met de zogeheten organ-on-a-chiptechnologie wordt een soort kunstorgaantje gemaakt, inclusief bloed dat er doorheen stroomt. Zo ontstaat een levensechte testsituatie voor medicijnen of het onderzoeken van ziekteprocessen.…
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Tycho de Graaf (nieuwe Universitair Docent) en Frank Bentvelzen en Ruben van Uden (nieuwe Ph.D.-fellows) bij Instituut voor Privaatrecht
Per 1 augustus is Tycho de Graaf gestart als Universitair docent bij het Instituut voor Privaatrecht. Daarnaast zijn per 1 september Frank Bentvelzen en Ruben van Uden verbonden als Ph.D-fellows aan het Instituut voor Privaatrecht. Zij vertellen over hun werkzaamheden en het onderzoek dat zij zullen…
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Media en interactie
Media & interactie is waar kunstmatige intelligentie en machine learning samenkomen met filosofie, cognitieve wetenschap en de creatieve kunsten. Voorbeelden van onderzoeksvragen in dit domein zijn: ‘Kan een algoritme naar menselijke maatstaven creatief zijn?', 'Kunnen creatieve processen, zoals het…
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Online Master’s Experience: Master Transfusion Medicine and Cellular and Tissue Therapies
Studievoorlichting