De wetenschappelijke onderbouwing van beleid wordt cruciaal geacht voor goed bestuur. Maar ondanks de overvloed aan beschikbare kennis uit onderzoek en evaluaties, weten we nog maar weinig over de daadwerkelijke invloed die dergelijke evidence heeft op overheidsbeleid. Het onderzoeksprogramma ‘Power…

How can we quantify the density of species within a community through environmental DNA concentrations?

Promotor: J. Schaye

Although nanoparticles are extensively used in various applications like consumer products and have most probably entered the environment, little is known about the effects of these particles on living organisms.

Does roadside management in the mid-west USA increase invertebrate diversity similar to practices in Europe?

This thesis manuscript explores the use of video games as tools for conceptual exploration and academic research.

Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri

The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

Promotor: G.P. van Wezel, Co-promotor: D. Claessen

Promotor: Prof.dr. J. Kuiper

Promotores: Prof.dr. G.A. van der Marel, M. van Heel

Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.

Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder

Membrane fusion is a vital process in living organisms and is mediated by zipper-like proteins.

Mycorrhizas are symbiotic associations between soil fungi and most plant species.

Promotor: R. Verpoorte, Co-promotores: Y.H.Choi, N.R. Mustafa

The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.

How soil microbial composition impacts structure and composition of the aboveground plant and animal communities?

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

In this thesis, the role of plant-mediated soil legacy effects in shaping aboveground plant-insect interactions was investigated.

Innovation plays an essential role in firms' competitiveness and long-term success. It varies from different types, ranging from run-of-the-mill innovation that brings incremental changes to existing technologies to radical innovation that breaks from existing trajectories.

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

A plasma is an ionized gas with very low electrical resistivity. As such, magnetic field lines are 'frozen in' and move with the fluid. Magnetic field lines that are linked, knotted and tangled, cannot be undone by the fluid motions.

Promotor: Koen Kuijken Co-promotor: Henk Hoekstra

To contribute to the body of knowledge aiming at a better coverage of ecosystem service assessment in LCA studies, this thesis dives into the challenges of incorporating existing ecosystem service methods within the impact assessment phase of the conventional LCA framework.

Heterogeneous catalysis is essential to many industrial applications. These catalysts are often comprised of supported nanoparticles, which contain various different surface sites.

In summary, the collective results described in this thesis show that nanoparticulate vaccines can be delivered intradermally by coated and hollow microneedles and evoke antigen-specific immune responses.

In this PhD study, I aim to deepen our understanding of the influence of major mycorrhizal types, namely arbuscular mycorrhizae (AM) and ectomycorrhizae (EM), on the global soil carbon cycle and their potential distribution changes under future environmental shifts.

Promotores: G.R. de Snoo, W.T. de Groot, Co-promotor: C.J.M. Musters

Mensen die de afgelopen drie maanden antibiotica hebben gebruikt, letten meer op negatieve gezichtsuitdrukkingen, blijkt uit onderzoek van postdoc Katerina Johnson en universitair docent Laura Steenbergen. Dit kan mogelijk verklaren hoe antibiotica het risico op het ontwikkelen van depressie vergroo…

Human vocal communication and music perception represent advanced cognitive skills, seemingly innate and universal. These faculties encompass a range of perceptual and cognitive abilities. Cross-species research sheds light on the origins of musicality by investigating whether these traits are shared…

For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.

n this PhD thesis, the recombination of different atomic lattices in stacked 2D materials such as twisted bilayer graphene is studied. Using the different possibilities of Low-Energy Electron Microscopy (LEEM), the domain forming between the two atomic layers with small differences is studied.

Promotor: M.T.M. Koper, Co-promotor: J.B.F. Juurlink

This thesis investigates how cell shape and collective behavior influence the dynamics and structure of biological tissues, which are crucial for understanding processes like embryonic development, tissue regeneration, and metastasis.

This thesis investigates the evolution and fate of gaseous exoplanets, which are continuously shaped by stellar activity across both short and long timescales.

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Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.

This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.

The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.

The origin and evolution of galaxies are closely tied to the cyclic feedback processes between stars and the interstellar medium (ISM).

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

Promotor: Prof.dr. H.S. Overkleeft

This PhD-thesis presents a study on micron-sized particles, so-called colloids. By controlling the chemical and physical properties of these particles, such as the interparticle interaction and the particles’ shape, colloids can act as building blocks that self-assembly into larger structures.

Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.

This PhD-thesis analyses the relationship between the parties’ choices in the CPB Netherlands Bureau for Economic Policy Analysis’ assessments of the election manifestos and coalition agreements over the period 1986-2017, and tries to explain this relationship.

A tidal basin is an inland sea which is almost entirely enclosed by land and connected to the open sea by a tidal inlet. Through the tidal inlets interaction takes place between the tidal basin and the open sea.

The European Council and the European Commission have a similar role in agenda setting. Both place issues on the EU agenda. However, these institutions have distinct designs. They have different political attributes (the European Council has considerably more political authority) and information-processing…