Het Leiden University Centre for the Arts in Society (LUCAS) is wereldwijd een van de weinige onderzoeksinstituten waar wetenschappers op het gebied van literatuur, beeldende kunst, architectuur, design en mediastudies samenkomen om onderzoek te doen naar de culturele productie van de westerse wereld,…

Vind jouw thuis bij LUC! Wij zijn gevestigd in het hart van Den Haag. Met ons eigen gebouw en internationale profiel biedt LUC een omgeving voor iedereen die op zoek is naar een interculturele ervaring en die een verantwoordelijke wereldburger wil worden.

Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.

The aim of this thesis is to expedite and ensure the systematic accuracy of clearance scaling from adults to paediatric patients, with a special focus on drugs undergoing hepatic metabolism.

In this course, you will explore the organs involved in our food digestion and discover the common causes of abdominal and pelvic pain. The latest graphics and animations will give you new insights and understandings of this part of the body.

Bachelor, Master

Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.

Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

Leiden University College The Hague (LUC) is het internationale honours college van de Universiteit Leiden. Het LUC The Hague biedt gemotiveerde en getalenteerde studenten van over de hele wereld een innovatieve Liberal Arts & Sciences bacheloropleiding.

In this thesis, we consider various (electro)chemical phenomena at surfaces and nanoparticles and their underlying atomistic processes, which we studied using first-principles methods such as density functional theory.

IoT technology poses serval opportunities to supply chains. This thesis employs grey correlation and forecasting models, system dynamics, agent-based modeling, and ex-ante LCA to investigate and quantify the opportunities and risks of IoT-enabled sustainable supply chain operations from both industrial…

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: G.J. Herczeg

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)

In this thesis, the role of mast cells in atherosclerosis and novel therapeutic strategies to inhibit atherosclerosis progression are discussed. The first part of the thesis specifically focuses on the relation between mast cells and advanced human atherosclerotic plaque characteristics.

Promotor: J.S. Kaastra Co-promotor: E. Constantini

Classical statistical methods, such as p-values, are difficult for researchers to apply correctly. They for example do not allow drawing conclusions from a study early, or for extending a study with extra research groups that want to make their data available later.

Promotor: Jaap Brouwer, Co-promotor: Remus Th. Dame

This thesis is a (biased) journey through very different topics in astrophysics: quasars and new populations of active galactic nuclei, gravitational waves from merging black holes, and protoplanetary discs around young stars.

In this thesis, I focused on studying the above- and belowground interactions of J. vulgaris from a plant-soil feedback (hereafter, PSF) perspective. I investigated the temporal variation of negative PSF and examined the effects of root-associated bacteria on plant performance and aboveground herbiv…

A single self-assembled semiconductor quantum dot in a high-finesse optical microcavity - the subject of this thesis - is an interesting quantum-mechanical system for future quantum applications. For instance, this system allows trapping of an extra electron and thus can serve as a spin quantum memory,…

Nanoparticles can be used as delivery systems for both small molecules and macromolecules such as proteins, peptides or oligonucleotides. This thesis focuses on the use of liposomes, nanometric vesicles formed by a lipid bilayer enclosing an aqueous core. Liposomes are highly versatile delivery syst…

Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…

Bij Leiden University College (LUC) in Den Haag staan ‘Global Challenges’ centraal. Global Challenges zijn de grote, maatschappelijke uitdagingen van de 21ste eeuw waar we gezamenlijk een oplossing voor moeten vinden, zoals klimaatverandering, armoede, ongelijkheid, vrede en recht. Onze opleiding is…

Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.

Promotor: H.J.A. Röttgering, Co-promotor: M. Haverkorn

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…

Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.

Over the past years it has been discovered that the population of extra-solar planets is large and diverse.

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

Vanaf de koloniale tijd tot heden hebben grote aantallen Javanen hun woonplaats verlaten om zich in andere delen van Indonesië of veel verder weg te vestigen. Vaak was deze spreiding gedwongen, vaak met traumatische gevolgen.

Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm

This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.

Dit deelproject pleit voor een nauwkeurige en forensische reconstructie van de financiële stromen van en naar de Sovjetrepublieken in Centraal-Azië in de naoorlogse periode.

Dit project bekijkt het Oudgrieks vanuit het perspectief van de alledaagse schrijvers. Een corpus van meer dan 60.000 Griekse teksten op papyrus, van privébrieven tot petities en contracten geeft ons toegang tot de Griekse taal zoals die werd geschreven door gewone mensen in de oudheid (van 300 v.Chr.…

This Thesis describes the synthesis of D-alanylated ribitol-based wall teichoic acids from S. aureus to probe their interaction with immune-binding partners.

Electoral Systems and Turnout: Evidence From a Regression Discontinuity Design. In dit artikel, gepubliceerd op de website SAGE research methods, bespreken auteurs Jaroslaw Kantorowicz en Tobias M. Hlobil hoe een Regression Discontinuity Design uitgevoerd kan worden.

This dissertation presents new cryptographic protocols, which can be divided into two families.

In dit artikel onderzoeken Thijs van Dooremalen en Philip Smith hoe het publieke discours over hittegolven is verschoven in Britse kranten.

Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)

The global agri-food system plays a critical role in food security and environmental issues.

Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua

In dit interdisciplinaire project worden data science technieken toegepast om de interactie tussen de Universiteit en stad Leiden (Town&Gown) kwalitatief en kwantitatief zichtbaar te maken vanaf 1575. Een van de mogelijke invalshoeken voor vervolgonderzoek is diversiteit, met name vanuit de internationale…

Irene Khan, expert op het gebied van mensenrechten, werpt een aantal vragen op: Wat kan men verstaan onder een ‘Culture of Justice’? Wie bepaalt wat 'Justice' is? Hoe realistisch is de bevordering van ‘Rule of Law’ en ‘Justice’ in landen waar sprake is van ernstige conflictsituaties en armoede?

Data theory research on the analysis on the multidimensional data

The Leiden University Centre for the Digital Humanities (LUCDH) invites applications from Leiden University staff and students for funding aimed at developing Digital Humanities activities.