249 zoekresultaten voor “density functional circulations” in de Publieke website
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Advances in 2D Material Synthesis, Transfer, and Device Integration
This thesis focuses on developing wafer-scale two-dimensional (2D) materials by combining synthesis, transfer, characterization, and device integration of graphene, hexagonal boron nitride (h-BN), and BN-doped amorphous carbon.
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
Control of infectious diseases poses continuous challenges for human health.
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Noonan and LEOPARD syndrome in zebrafish: molecular mechanisms and cardiac development
Promotor: Prof.dr. J. den Hertog
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Abstract Behavioral Specification: unifying modeling and programming
We strive to address the challenge of constructing a modeling language to write software which can take advantage of recent hardware developments (multicore, cloud) without compromising in its abstraction levels.
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Adaptive Streaming Applications: Analysis and Implementation Models
Promotor: Prof.dr. E. Deprettere
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Cryo Electron Tomography Studies On Bacterial Chemosensory Arrays
Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.
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Design and development of conformational inhibitors and activity-based probes for retaining glycosidases
Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.
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The role of the Arabidopsis AHL15/REJUVENATOR gene in developmental phase transitions
This thesis describes the functional analysis of the Arabidopsis AHL15 gene.
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Cellular Forces: Adhering, Shaping, Sensing and Dividing
Promotor: Prof.dr. T. Schmidt
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A fixed point approach towards stability of delay differential equations with applications to neural networks
Promotor: S.M. Verduyn Lunel, Co-Promotor: O.W. van Gaans
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Reverse engineering of drug induced QT(c) interval prolongation: Towards a systems pharmacology approach
Promotor: M. Danhof Co-promotor: O.E. Della Pasqua
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Stochastic resetting and hierarchical synchronisation
Stochastic resetting is simple enough to be approached analytically, yet modifies stochastic processes in a non-trivial way.
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The dynamic organization of prokaryotic genomes: DNA bridging and wrapping proteins across the tree of life
Every organisms in the tree of life faces the same challenge: the length of its DNA exceeds the volume of the cell it needs to fit in. Several strategies have evolved to solve this problem, one of them being the expression of proteins that bind and organize the DNA.
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Exploring charge transport properties and functionality of molecule-nanoparticle ensembles
Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen
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Ecological functions and environmental fate of exopolymers of Acidobacteria
Acidobacteria is a widely distributed phylum but their functional roles in ecosystem processes are still largely elusive.
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Impact of land use changes on the human-elephant conflict
Promotor: G.R. de Snoo, W. Kustiawan, Co-promotor: H.H. de Iongh
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Acquired resistance in pancreatic cancer: characterization and exploration of actionable targets of a multifactorial disease
Pancreatic ductal adenocarcinoma (PDAC) is among the cancers with the highest mortality rate, despite a relatively low incidence.
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Blueprints of Disease: Precision Platforms for Modelling Breast Cancer
Breast cancer (BC) is a clinically and biologically heterogeneous disease.
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Of Marks and Men
Daniel Soliman verdedigde zijn proefschrift op 15 september 2016.
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Time is of the essence: investigating kinetic interactions between drug, endogenous neuropeptides and receptor
Promotor: A.P. IJzerman Co-promotor: L.H. Heitman
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Synthesis of oligosaccharide libraries from GBS capsular polysaccharides for structure-based selection of vaccine candidates
Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.
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Systems pharmacology of the endocannabinoid system
In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).
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The impact of defense hormones on the interaction between plants and the soil microbial community
The soil ecosystem consists of the largest reservoir of biodiversity on Earth.
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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Reactivity and Selectivity in Glycosylation Reactions
The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.
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Resolving the Dynamic Structure of Chlorosomes in Green Sulfur Bacteria by MAS NMR
Understanding how nature captures and transfers solar energy is essential both for elucidating biological photosynthesis and for guiding the design of artificial light-harvesting systems.
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Metabolomics Insights into the Gut Microbiome and Infants with Cow’s Milk Allergy
The rapid expansion of research on human gut microbiome in recent decades has highlighted its role in human metabolism, immune regulation, and behavior.
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The unexplored functions of Toll-like receptor signaling: Immunometabolism, development and microbiome interactions
Toll-like receptors (TLRs) are central components of the innate immune system, functioning as pattern recognition receptors that detect microbial- and damage-associated molecular patterns and initiate antimicrobial and inflammatory responses.
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Mathematical models for mechanically induced morphogenetic pattern formation
During the development of the (human) body from a single fertilized egg, organs and structures must form. The development and growth of biological forms is called morphogenesis.
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Images of Galois representations
Promotores: S.J. Edixhoven, P.Parent
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Dynamical Gibbs-non-Gibbs transitions: a study via coupling and large deviations
Promotores: F.H.J. Redig, W.T.F. den Hollander
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Evolution of Au(111) Electrode Surface in Different Electrolytes and Conditions Studied with a Home-made EC-STM
In this study, we investigated the electrochemical behavior and surface evolution of Au(111) electrode under different conditions and electrochemical techniques, using a homemade electrochemical scanning tunneling microscope (EC-STM), revealing the intricate interplay between surface roughening, atom…
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Farmacologische conditionering van oxytocine reacties in gezonde vrijwilligers
Is het mogelijk om oxytocine reacties bij gezonde personen farmacologisch te conditioneren en de neurale circuits te identificeren die aan deze conditionering ten grondslag liggen?
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C-SCAPE - Sandy strategies for sustainable coastal climate change adaptation
What is the optimal design of sandy solutions for sustainable climate change adaption, from an ecological, biophysical and societal point of view?
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Diversity and Functional Potential of the Sorghum Root Microbiome to Control Striga hermonthica
Promotie
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exercise therapy in people with axial spondyloarthritis and severe functional limitations
Promotie
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Remote (sensing) functional biodiversity: exploring drivers of trait variation and spectral variability
Promotie
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Advancing Fertility Preservation: Structural and Functional Insights into the Human Ovary
Promotie
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Urban green infrastructure for biodiversity and ecosystem services
Urbanisation is steadily increasing with estimates expecting that 68% of the global population will live in cities by 2050. To accommodate the rural to urban transition, large quantities of land are transformed from natural to urban lands.
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Zenith subsidie voor Hermen Overkleeft
Hermen Overkleeft ontving samen met Bobby Florea een Zenith subsidie van het Horizon-programma van het Nederland Genomics Initiative voor hun voorstel Quantative functional enzyme profiling: a versatile strategy to monitor disease progression and to validate new therapeutic strategies'.
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Rescue of Business in Insolvency Law
The ultimate aim of this project (initiated by the European Law Institute) is to design a framework that will enable the further development of coherent and functional rules for business rescue in Europe.
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Temperature effects on genetic and physiological regulation of adaptive plasticity
Promotor: P.M. Brakefield
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NWO-subsidie voor opsporing dementie in een vroeg stadium
NWO heeft een Onderzoekstalentbeurs toegekend aan de Leidse psycholoog Jeffrey Durieux. Hij doet onderzoek naar mogelijkheden om dementie in een vroeg stadium op te sporen door verschillen in netwerken in onze hersenen te identificeren.
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Masterstudenten European Law winnen Migratie Annotatiewedstrijd 2020
Op dinsdag 1 december hebben masterstudenten European Law Pien Offerhaus en Carina van Os de Migratie Annotatiewedstrijd 2020 gewonnen.
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Bernhard Hommel benoemd tot senator Leopoldina
Bernhard Hommel is benoemd tot senator van de Duitse Nationale Academie van Wetenschappen, de Leopoldina. Hommel is nu voorzitter en spreker van de sectie Psychology and Cognitive Sciences en representeert deze sectie in de senaat van de Leopoldina.
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Minicollege: Hersenpaden van autistische jongens verschillen
Dr. Marcia Goddard ontdekte dat de hersenen van 2 groepen jongens met symptomen van autisme verschillen. Dit is nooit eerder aangetoond. ‘Blijkbaar is er binnen het autisme spectrum op belangrijke punten variatie in de hersenmechanismen die tot bepaald gedrag leiden.’ Dit pleit voor behandeling op maat…
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Studenten International Studies ontvangen diploma
Precies 194 studenten ontvingen op vrijdag 26 augustus hun bachelordiploma International Studies.
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Zomer vol congressen in Leiden
Het wordt een zomer vol conferenties bij de Faculteit Geesteswetenschappen in Leiden. De komende maanden is er voor ieder wat wils te doen aan de universiteit, met name op het gebied van talen en culturen van Afrika en het Midden-Oosten.
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Haarlemse middelbare scholieren bezoeken Babylab Leiden
Leerlingen van het Coornhert Lyceum uit Haarlem bezochten samen met hun docent Roos Bannenberg het Babylab Leiden. De 5-vwo’ers volgen modules van 10 weken voor wetenschapsoriëntatie en zij konden zich lastig voorstellen hoe onderzoek met baby's eruit ziet. Het Babylab Leiden gaf uitkomst.