Promotor: Prof.dr. E. Eliel, Co-Promotor: M.J.A. de Dood

Galaxies in the local Universe fall into two main categories of spirals and ellipticals. In this Thesis, we explore the structural evolution of galaxies into this bimodal distribution.

Global Environmental Extensions Multi-Regional Input-Output (EE-MRIO) analysis is often used to analyze how changes in global and national demand for products lead to socioeconomic and environmental impacts at the national level.

The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity.

While ecosystems have concrete benefits for human society, these benefits are typically overlooked in decision-making.

This thesis explores the theoretical and observational properties of distant massive galaxies that harbour active black holes in their centres and shine brightly at radio wavelengths.

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

This thesis investigates how cell shape and collective behavior influence the dynamics and structure of biological tissues, which are crucial for understanding processes like embryonic development, tissue regeneration, and metastasis.

Human civilization consumes a huge amount of fossil fuels, which has resulted in an atmospheric CO2 level which has not been higher in over 800 millennia.

This thesis describes the role of pollution, specifically neonicotinoid insecticides, as an actor of the ongoing biodiversity decline.

Promotores: G.W. Canters, T.J. Aartsma

Promotores: Prof.dr. E.F. van Dishoeck, Prof.dr. C.P. Dullemond

This thesis investigates opinion dynamics on random graphs through the lens of the voter model, a classical interacting particle system used to describe how consensus emerges in networks.

Green hydrogen is produced via a process called water electrolysis. During electrolysis water is split into oxygen and hydrogen.

Promotor: Jelle S. Kaastra Co-promotor: Jelle de Plaa

A dense region of a gaseous and dusty cloud collapses to form a protostar surrounded by a disk and an envelope. This thesis uses both observations and models to study physical and chemical conditions of these protostellar systems which are likely where planets start to form.

Promotor: Roeland M.H. Merks

Advanced UHF MRI techniques provide powerful tools for studying the zebrafish brain, an emerging model in neurological research. In this work, various MRI and localized MRS methods are optimized and employed for UHF strength for studying the zebrafish brain.

The specialisation Science Communication and Society (SCS) concerns science communication in a broad sense. The program focuses on the link between science and society and covers knowledge and skills in the field of science communication.

This thesis examines the link between simple molecules and the underlying structure and chemistry within protoplanetary disks - the birthplaces of planets.

The transition to electric vehicles (EVs) reduces vehicle emissions to combat climate change. EVs raise concerns regarding the production of lithium-ion batteries and related emissions; while batteries can also provide energy storage services for the electricity system.

Promotor: Prof.dr. V. Icke, Co-Promotor: T.I. Madura

Over the last three decades, the discovery of exoplanets has revealed the boundless variety of worlds beyond our own Solar System⁠. Majority of planetary systems contain short-period planets that are larger than Earth but smaller than Neptune⁠.

Thirty years ago, mutations in the BRCA1 gene were first linked to hereditary breast and ovarian cancer, establishing a genetic basis for cancer development.

Cardiovascular diseases are a leading cause of death worldwide, and better models are urgently needed for disease progression studies and drug development.

Promotor: Prof.dr. P.G.L Klinkhamer, Co-promotor: K. Vrieling

Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

n this PhD thesis, the recombination of different atomic lattices in stacked 2D materials such as twisted bilayer graphene is studied. Using the different possibilities of Low-Energy Electron Microscopy (LEEM), the domain forming between the two atomic layers with small differences is studied.

Promotor: Prof.dr. M.L. van Heck, Co-Promotor: B.P. Tighe

Hospital pharmacies face significant challenges: the demand for sterile drug reconstitutions is increasing, while specialized personnel remain scarce. Automation offers a potential solution, but its practical implementation in hospitals is still unclear.

Nietzsches beroemdste en beruchtste boek Aldus sprak Zarathoestra is misschien het meest gelezen, maar waarschijnlijk ook het minst begrepen boek uit Nietzsches oeuvre. Zelf beschouwde hij het als zijn hoogtepunt. Hij noemde het een symfonie, een heilig boek, een vijfde evangelie en zelfs het grootste…

One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…

The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).

Promotors: Prof.dr. T.H.W. Bäck, Prof.dr. B. Sendhoff (Technische Universität Darmstadt)

We study the interplay of topology and geometry with chirality for several passive and active systems, employing both analytical and numerical methods.

Promotor: Prof.dr. E Gittenberger, Co-Promotores: C.H.J.M. Fransen, B.W. Hoeksema

This thesis is devoted to an in-depth examination of the various effects of disorder in the cuprate high-temperature superconductors.

Control of infectious diseases poses continuous challenges for human health.

Promotor: Prof.dr. T.H.W. Bäck

Promotor: Prof.dr. J. den Hertog

Continuous optimization is never easy: the exact solution is always a luxury demand and the theory of it is not always analytical and elegant.

Prof.dr. J. Memelink

Promotor: J.W.M. Frenken

Atherosclerosis is the most prominent underlying pathology of cardiovascular disease and an important cause of major adverse cardiovascular events.

In this thesis, we show how MRFM can usefully contribute to the field of condensed-matter.

Promotoren: R. Tijdeman, A.K. Lenstra, Co-promotor: H.J.J. te Riele

Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.