Het Central Innovation District (CID) vormt het economisch hart van de stad Den Haag .

Religion and ethnicity are inextricably linked in discourse within and about Central Asia. One common narrative suggests that as a result of differences between historically sedentary and nomadic populations, ethnic Tajiks and Uzbeks are naturally more religious and more likely to radicalise than their…

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

Houden en fokken van proefdieren voor onderzoeks- en onderwijsdoeleinden.

Nout Wellink sprak over de rol van de centrale bank in het huidige roerige financiële klimaat. Daarbij gaat hij ook in op de gewijzigde kapitaaleisen die voor banken gelden.

In Chapter 1 we provide some background information about modular forms, describe the correspondence between half-integral and integer weight modular forms and explain how the coefficients of half-integral weight modular forms encode the central values of L-functions of twisted modular forms.

In times of hardships or crisis, local people know how to deal with it using their resourcefulness. Although efforts are sometimes made by the government to help them, they are fully aware that community support is at least equally important.

Dit artikel belicht hoe betere monetair-fiscale coördinatie zich naar verwachting zal ontwikkelen in zeer verschillende politiek-economische contexten.

In dit artikel onderzoeken Adriana Cerdeira en Dovile Rimkute hoe bepaalde dynamieken het gedrag van banken bepalen.

In dit artikel onderzoeken Antoaneta Dimitrova en anderen wat demonstranten in Midden- en Oost-Europa motiveert.

Central Limit Theorem associated to a particular case of ergodic total automorphisms. Finally, Chapter 6 proves that the isoperiodic foliation is connected for a meromorphic differential with three poles on a torus.

Leiden University would like to express its concern about the proposed Hungarian higher education draft law, which, if adopted, would make the functioning of Central European University (CEU) in Budapest nearly impossible. These changes would endanger the academic freedom vital for CEU’s continued operation…

The Department of Historical Studies at Central European University (Vienna, Austria) is pleased to announce its call for applications for the 2025/2026 academic year. The deadline is February 1, 2025.

In this thesis, I targeted the orchid genus Lepanthes, one of the six genera of angiosperms that surpasses 1,000 species in the Neotropics, as a study model to investigate the evolutionary processes that promoted species diversifications.

This dissertation consists of two parts, each of which considers a different research area related to random interval maps. In the first part we are interested in random interval maps that are critically intermittent.

De Campus Den Haag van de Universiteit Leiden gaat uitbreiden in het zogenoemde Central Innovation District in het centrum van Den Haag. Er zijn plannen voor een Campusboulevard met een nieuw universiteitsgebouw in het gebied tussen het Prins Bernhardviaduct en de Schedeldoekshaven.

Accurate prediction of the unbound drug concentration-time profile at the CNS target site is crucial for the assessment of the right drug concentration-effect relationship. PBPK models have supported the PK prediction of the CNS target sites and the translation of PK data between species and between…

This thesis focuses on enhancing predictions of central nervous system drug exposure using the LeiCNS-PK3.0, a physiologically based pharmacokinetic model.

CEU's Department of Historical Studies is organizing two online info sessions for anyone interested in applying to their MA and PhD programs on Friday 6 and 13 December and Friday 10 and 17 January.

The subject of this thesis, ‘Approach to Markov Operators on Spaces of Measures by Means of Equicontinuity’, combines an analytical and probabilistic approach to Markov operators.

This thesis explores Breaking of Ensemble Equivalence (BEE) in random graph models by examining the spectral properties of adjacency matrices. The goal is to identify spectral characteristics that differentiate random graph ensembles, enhancing the understanding of complex network structures and beh…

This thesis explores Breaking of Ensemble Equivalence (BEE) in random graph models by examining the spectral properties of adjacency matrices. The goal is to identify spectral characteristics that differentiate random graph ensembles, enhancing the understanding of complex network structures and beh…

Het Westen, de VS en de EU voorop, probeert voor Rusland de prijs van de oorlog op te voeren, door Oekraïne met geld en wapens te steunen en door Rusland uit te sluiten van financiële markten. Maar een voortdurende anti-Russische politiek, betoogt politicoloog Hans Oversloot (Universiteit Leiden), is…

Lezing

Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.

Plants, are sessile organisms, have developed strategies to adapt to changes in their environment, in part by altering their growth and development.

Following the Big Bang, structure in the Universe started collapsing under the force of gravity. This resulted in the formation of the first stars, galaxies and clusters of galaxies.

Promotor: Prof.dr. G.R. de Snoo

The increasing competition in the automotive industry requires the tailored, swift development of technologically sophisticated vehicles. Therefore, the computationally expensive state-of-the-art simulation technologies are combined with optimization algorithms. An example of a real-world optimization…

Het Perzisch en de Perzische poëzie zijn nauw verbonden met de geschiedenis van Centraal-Azië. Sommige middeleeuwse dichters werden later door één staat geclaimd, maar hun invloed was grenzeloos. Dat stelt Gabrielle van den Berg, hoogleraar Cultuurgeschiedenis van Iran en Centraal-Azië, in haar oratie…

In this project of the Center for Public Values & Ethics (CPVE) ongoing research is conducted on the history of advice to Dutch central government by so-called State committees from 1814 to 2014. State committees have been installed by Dutch central government since 1814 to provide expert advice, research…

The impact of the phenotypic plasticity of P. aeruginosa and the distinct CF lung microenvironments on antibiotic drug effects and resistance remains poorly understood.

How are new drugs developed? This question is central to the Minor Modern Drug Discovery (MDD), which covers the entire trajectory from disease to drug molecule and vice versa. The various research groups involved offer a complementary and interdisciplinary perspective by connecting the diverse subjects…

In this Yearbook you will find some fascinating examples of what was done in 2021, not only by ourselves, but also by our international colleagues.

Het Instituut Politieke Wetenschap heeft een zeer divers onderzoeksprogramma. Dit programma dient twee doelen: het bevorderen van de eenheid van het Instituut als een intellectuele gemeenschap van sociale wetenschappers en politicologen en om collega’s met overlappende interessegebieden in staat te…

Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.

The research group Science Communication and Society aims to understand how science communication works to improve the interaction between science and society. Central themes are ‘Bridging the gap between experts and the general public’ and ‘Evaluating Science Communication’.

This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: M.R. Hogerheijde

Promotor: G.A. van der Marel, Co-promotor: D.C. Codée

This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

To study how planetary systems come into existence we study much younger systems still in formation.

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

The plant hormone auxin regulates plant growth and development through polar cell-to-cell transport-generated maxima and minima. PIN FORMED (PIN) auxin efflux carriers determine the direction of this auxin flow through their asymmetric placement on the plasma membrane (PM).