Data worden steeds belangrijker in de topsport. Maar kunnen data op het allerhoogste niveau het verschil maken? Sportdatawetenschapper Rens Meerhoff denkt van wel, zo vertelt hij bij De Kennis van Nu.

Onderzoekreeks van de Afdeling Economie van de Universiteit Leiden op het raakvlak van economie en recht.

The work described in this Thesis is focused on the assembly of oligosaccharide fragments derived from a fungal polysaccharide, galactosaminogalactan (GAG) and fragments of the exopolysaccharide Pel, generated by Pseudomonas aeruginosa.

This thesis consists of two subjects, that are both a consequence of radiation pressure.

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

In this thesis, classes of strongly interacting quantum field theories, have been studied.

The thesis deals with the study of giant radio galaxies (GRGs), which are radio galaxies of megaparsec sizes.

Sociaaleconomisch Beleid: Empirische Analyse, een nieuw vak voor bachelorstudenten Bestuurskunde die de richting Economie, Bestuur en Management volgen.

Waarom Google Maps gebruiken als je je fietsroute ook kunt berekenen aan de hand van je eigen data. Statisticus en wielrenner Alexander Dürre ziet overal statistieken in. Hij analyseert gegevens van voetbalwedstrijden en berekent de mogelijke winnaars van wielerwedstrijden. ‘Als ik tijd te veel heb,…

Prof. Ottervanger, emeritus hoogleraar Europees recht en Nederlands Mededingingsrecht, heeft 36 onherroepelijke uitspraken van de rechter over ACM-besluiten in mededingingszaken geanalyseerd. Het rapport is meegenomen bij de evaluatie van de ACM die door het ministerie van Economische Zaken en Klimaat…

Schaatscoach en bewegingswetenschapper Jac Orie legt al vijftien jaar alles vast over de prestaties van 'zijn' schaatsers. Dankzij datawetenschapper Arno Knobbe, die de verzamelde data op nieuwe manieren doorberekent, kan Orie zijn team nog slimmer trainen in de aanloop naar de Olympische Winterspelen…

Of een bacterie nuttig of schadelijk is voor een plant is nu eenvoudig en goed te voorspellen met de nieuwe software bacLIFE. Door de intuïtieve interface maakt het de geheimen van bacterie-genen veel toegankelijker. Een groep Leidse biologen presenteerde dit staaltje bioinformatica in Nature Commun…

Op 29 november ontvangt Stéphanie van der Pas de ASML Afstudeerprijs voor Wiskunde bij de Koninklijke Hollandsche Maatschappij der Wetenschappen (KHMW) te Haarlem. Ze bewees dat een nieuwe methode om een onderzoeksmodel te kiezen beter werkt dan de gebruikelijke standaardmethode.

In light of climate change, it is crucial to determine whether plant species can adapt to future climates to avoid extinction. Plants adapt to various conditions by altering their functional traits, such as leaf size or photosynthetic rate. Some traits appear linked and vary together between species,…

Studievoorlichting

Hoe vormen cellen samen een structuur? Promovenda Daphne Nesenberend laat met wiskunde zien hoe krachten en samenwerking tussen cellen leiden tot structuur – en hoe simulaties en experimenten elkaar aanvullen.

This study has been carried out in the community of Sukamiskin, a kelurahan (‘village’) in Bandung, the Capital of West Java Province, located in the Sunda Region of Indonesia.

Promotor: G.A. Persoon, Co-promotor: H.H. de Iongh

The confinement of molecular catalysts in metal-organic frameworks has the potential to lead to significant improvements in selectivity, long term activity and catalyst stability.

In this thesis, we study travelling waves in stochastic reaction-diffusion equations. We extend techniques from the deterministic theory for travelling waves to apply to the stochastic version, which allows us to compute the stochastic wave speed and shape, and draw conclusions on the stability of the…

Met anderhalf miljoen euro van de Europese Commissie gaat industrieel ecoloog Stefano Cucurachi op zoek naar duurzamere productiemethoden voor de farmaceutische industrie. Het Italiaanse farmabedrijf Angelini Pharma wil de resultaten gebruiken om haar productieproces duurzamer te maken.

The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.

This thesis has described novel synthetic methods to produce a variety of (glyco)peptides and their application in the study of various immunological processes.

Over the past years it has been discovered that the population of extra-solar planets is large and diverse.

Promotor: M. Ubbink, Co-promotor: G. Siegal

In this thesis we investigated the ability of two-photon multifocal microscopy for single-molecule microscopy in live cells and organisms.

It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

This thesis is largely an experimental study on the formation of solid-state simple and complex organic molecules in the H2O-rich and CO-rich ice phases of dense interstellar clouds and dark cores.

Automated Machine Learning (AutoML) is widely used to automatically build a suitable practical Machine Learning (ML) model for an arbitrary real-world problem, reducing the effort of practitioners in the ML development cycle for real-world applications. Optimization is a key part of a typical AutoML…

This thesis focused on the exploration of monolayer graphene as a membrane in direct methanol fuel cell (DMFC) applications, with improvements achieved through plasma exposure or damage- free chemical functionalization.

My PhD research is devoted to studies of the conjectural cluster-algebraic symmetry in the theory of topological string, which is the simplest, however already non-trivial sector in the theory of string.

The work in this thesis has been focused on two subjects. The first is the assembly of alginate oligosaccharides and the generation of building blocks for the enzymatic synthesis of alginate, and the second is the total synthesis of large fragments of the zwitterionic SP1 polysaccharide.

Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)

The parabolic Anderson model (PAM), which is the Cauchy problem for the heat equation with random potential. The PAM is a mathematical model that describes how mass (i.e. matter or energy) flows in a medium in the presence of a field of sources and sinks.

Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.

This dissertation contains four works during my PhD. Different biomaterials have been designed based on coiled-coil peptides. These biomaterials have a range of applications, inclusing drug delivery, cell sorting to cell-cell fusion.

With an emphasis on developing novel miktoarm star polymers termed PeptoMiktoStars, this thesis leverages asymmetric polymeric polypept(o)ide frameworks to advance their effectiveness in delivering hydrophobic drugs and nucleic acids.

Despite being the second largest transmembrane protein family after GPCRs, the SLC superfamily has only gained significant attention in early drug development over the past decade.

Software development is a complex process. It is important that software products become stable and maintainable assets.

Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.

In this Thesis, novel charge induction mechanisms of ionic liquids are treated, tested and experimented on complex oxides, in particular cuprates.

Promotores: Prof.dr. M. Franx, Prof.dr. P.G. van Dokkum (Yale University)

A structural investigation of coiled coil peptides used as membrane fusogens, mimicing naturally occuring coiled-coil fusion proteins. Synthetic modifications have been made to alter lipid attachment, secondary structure and to insert photoactive azobenzene moieties for active control over coiled coil…

Soil biodiversity is of great importance for the maintenance of multifunctionality in terrestrial ecosystems.

The focus of this thesis is on the technical methods which help promote the movement towards Trustworthy AI, specifically within the Inspectorate of the Netherlands.

The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.

In this thesis, we have used numerical approaches to study the effects of translational symmetry breaking on strange metallic systems as realised by the holographic duality⁠.