Gaucher disease is a rare metabolic disorder, in which a mutation of the enzyme glucocerebrosidase (GBA1) causes buildup of its substrate glucosylceramide and the deacylated counterpart glucosylsphingosine in lysosomes.

For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.

Religion, Philosophy, and the Pre-modern World

How should jurisdictions, both on the national and on the supra-national level, handle the interaction between public and private law where it regards the regulation of financial markets?

This thesis has described novel synthetic methods to produce a variety of (glyco)peptides and their application in the study of various immunological processes.

Op 23 juni 2020 verdedigde Santy Kouwagam haar proefschrift 'How lawyers win land conflicts for corporations: Legal Strategy and its influence on the Rule of Law in Indonesia'. Het promotieonderzoek is begeleid door promotoren prof.dr. A.W. Bedner en prof.dr. C.E. von Benda-Beckmann.

In this thesis we use Josephson and noise scanning tunneling microscopy for the study of conventional, unconventional (iron-based) and disordered superconductors. On the one hand, Josephson scanning tunneling microscopy allows us to directly visualize the superfluid density with high spatial resolut…

Promotor: W. Jiskoot, Co-promotor: A. Kros

Promotor: M. Ubbink, Co-Promotor: R. T. Dame

The use of N fertilizers has increased worldwide in the past century. While this increased input of N has increased food productivity, it has also contributed to decreases in biodiversity, soil quality and environmental health, including increases in greenhouse gas emissions.

This dissertation contains four works during my PhD. Different biomaterials have been designed based on coiled-coil peptides. These biomaterials have a range of applications, inclusing drug delivery, cell sorting to cell-cell fusion.

Promotor: Prof.dr. J.N. Kok

In the past decade many population studies have been performed with the Atacama Large Millimeter/submillimeter Array (ALMA) to understand the bulk properties of protoplanetary disks around young stars. These population studies mostly consisted of low mass stars, with relatively few of the disks around…

Promotores: Prof.dr. M. Franx, Prof.dr. P.G. van Dokkum (Yale University)

Kunnen we van quantum-verrassingen quantum toepassingen maken? Kunnen we het leven onderzoeken en opbouwen vanuit de nano-schaal?

Carbohydrates, alongside proteins and nucleic acids, constitute a crucial and versatile family of biomolecules present in all life forms. They manifest as monosaccharides, oligosaccharides, and polysaccharides, covalently bonded to proteins and fats. Carbohydrates are integral to plant and arthropod…

When a star is born in our Galaxy, it is quite likely that it has formed within a massive cluster, which hosts numerous high-mass stars bathing their lower mass neighbours in UV radiation.

In this thesis, we address two problems concerning the tautological rings of the moduli space of curves.

Understanding how chemical complexity emerges during star formation requires connecting molecular material preserved in interstellar ices with that observed in the gas phase after protostellar heating begins.

Promotores: P. Stevenhagen, L. van Geemen Co-promotor: R.M. van Luijk

Kidney transplantation is a major advance of modern medicine. This course will give you state of the art updates about what used to be an experimental, risky, and very limited treatment option more than 50 years ago and is now routinely performed in many countries worldwide.

Staatsrechtelijk analfabetisme Wie de politiek sindsdien volgt, zou misschien geneigd zijn om een stap verder te gaan en te spreken over staatsrechtelijk analfabetisme. Het lijkt er soms wel op dat vele spelers in het politieke veld zich niet meer bewust zijn van de regels van het spel en de achterliggende…

African oral literatures, new media and technologies: challenges for research and documentation

De abortuswetgeving in de Verenigde Staten staat op het punt om strenger te worden. In het radioprogramma OVT vertelt universitair docent Sara Polak waarom abortus zo’n belangrijk politiek thema is geworden.

The work described in this thesis focuses on the development of linear or cyclized peptide probes against protein N-methyltransferases to characterize their specific binding behavior, providing further binding details for inhibitory activity study.

The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.

In this top-rated course, you will learn how the European Union prepares and decides on policy, and how policy is transferred to member states and implemented by various authorities. It discusses the challenges of the European multi-level governance structure and the main causes of policy failure or…

This thesis attempts to interrogate post-1991-2015 political development in Ethiopia, focusing on the political discourses espoused by the government and opposition, using the discourse analysis method and securitization theory.

Leiden University College The Hague (LUC) biedt een 3-jarige bacheloropleiding aan waarin je je focust op Global Challenges; grote uitdagingen waar de mensheid mee te maken heeft: Vrede & Rechtvaardigheid, Diversiteit, Duurzaamheid en Welvaart. Je hebt ruimte om de opleiding zo in te richten als je…

Leiden University College The Hague (LUC) biedt een 3-jarige bacheloropleiding aan waarin je je focust op Global Challenges; grote uitdagingen waar de mensheid mee te maken heeft: Vrede & Rechtvaardigheid, Diversiteit, Duurzaamheid en Welvaart. Je hebt ruimte om de opleiding zo in te richten als je…

Overzicht van de vacatures bij de afdeling Economie.

Lezing

The Hague Journal of Diplomacy (HJD) sluit 2020 af met een gratis uitgave over de impact van de coronacrisis. Dertien auteurs op vier continenten schrijven over ‘Diplomacy after Covid19’.

The thesis mainly contributes to the characterization of Majorana fermions as they appear in the Condensed Matter context.

De Leiden Teachers’ Academy organiseert jaarlijks een symposium over onderwijsvernieuwing aan de Universiteit Leiden.

Subproject of the ERC project 'Challenging the Liberal World Order from Within: The Invisible History of the United Nations and the Global South'.

Faciliteiten waar LIBC leden gebruik van kunnen maken (in het Engels):

De Tweede Kamer vraagt om advies van de Raad van State over het combineren van het Tweede Kamerlidmaatschap met een post in het kabinet. Dat wijst er volgens Boogaard op dat Nederland toegroeit naar een constitutioneel hof.

Er is een nijpend tekort aan medicijnen. Volgens onderzoek van NRC is bijna één op de zeven Nederlandse patiënten aangewezen op geneesmiddelen uit het buitenland. Promovendus Koosje van Lessen Kloeke sprak over dit tekort met Mr.: ‘De Nederlandse geneesmiddelenwetgeving rammelt.’

Lecturer Andrew Gawthorpe of Leiden University discusses in The Conversation the growing influence of far-right activist Laura Loomer in Donald Trump’s administration.

Computational thinking, programming, and algorithms form the basic of many of the things that are shaping our world, the way we work, interact, organize ourselves, and even spend our free time with social networks, streaming media, and games. And this transformation is far from being complete, it is…

Webinar with Q&A

Atoms and molecules are the basic units of matter. If we keep dividing a bar of gold or a glass of water into smaller parts, at the end we are left with a single gold atom or a water molecule.

Promotor: Prof.dr. S. Haring

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

Carbonaceous asteroids preserve a record of early solar system processes, where minerals and organic molecules, like polycyclic aromatic hydrocarbons (PAHs), offer clues to planetary evolution and prebiotic chemistry.

Promotor: S.M. Verduyn Lunel

To study how planetary systems come into existence we study much younger systems still in formation.