Balsaminaceae is a diverse plant family characterized by a huge floral morphological diversity.

In this Yearbook you will find some fascinating examples of what was done in 2021, not only by ourselves, but also by our international colleagues.

Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.

Promotores: B. van de Water; P. Hogendoorn; J. Bovée Co-Promotor: E.H.J. Danen

Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe

Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.

Promotor: Prof.dr. J.N. Kok, Co-promotor: A.J. Knobbe

Every organisms in the tree of life faces the same challenge: the length of its DNA exceeds the volume of the cell it needs to fit in. Several strategies have evolved to solve this problem, one of them being the expression of proteins that bind and organize the DNA.

Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.

Promotor: K.J. Batenburg

The sequence-dependence of biomolecular interactions involving nucleic acids and proteins is essential for numerous processes inside the cell. Insights into the underlying molecular mechanisms have been obtained using various biochemical and biophysical methods on two different levels — bulk and sin…

Promotor: E.F. Smets Co-promotor: J. Geml

Promotores: J.N. Kok, H.J. Hoogeboom

Complex Organic Molecules (COMs) have been detected in objects across different stages of stellar evolution.

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

Marine sponges are important members of reef ecosystems, as they play ecological roles that are essential for the health of the reef.

Why do black holes emit thermal radiation? And how does a closed quantum system thermalize?

Promotor: B.van de Water, Co-promotor: L.S.Price

The plant hormone auxin plays a central role in the growth and development of plants. Auxin acts in a concentration dependent manner and polar cell-to-cell transport of this hormone determines its distribution in the tissues of plants. This polar auxin transport is mediated by several families of auxin…

In this PhD-thesis several new and existing data science application are described that are particularly focused on applications for tax administrations.

In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.

Where does the urge to collect come from? What are the explicit or underlying reasons for gathering large amount of objects?

Promotor: Prof.dr. E. F. van Dishoeck

The demand for neodymium-iron-boron (NdFeB) magnets is rapidly growing, while the neodymium supply chain is under pressure. Recycling can alleviate these issues. This thesis investigates the potential for deploying novel magnet recycling technologies and their environmental consequences.

Het doel van het RAISE Onderzoek is om te onderzoeken hoe veerkrachtige mensen omgaan met stress. We kijken specifiek naar hoe belangrijke biologische systemen, zoals de HPA-as en het immuunsysteem, samenwerken met de hersenen en de sociale omgeving om veerkrachtig functioneren na moeilijkheden in de…

In this thesis we explore machine and deep learning approaches that address keychallenges in high dimensional problem areas and also in improving accuracy in wellknown problems. In high dimensional contexts, we have focused on computational fluid dynamics (CFD) simulations.

A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.

Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.

Promotor: Prof.dr. E. Smets, M. Stech

This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.

Time-series forecasting through modelling sequences of temporally dependent observations has many industrial and scientific applications. While machine learning models have been widely used to create time-series forecasting models, creating efficient and performant time-series forecasting models is…

We have conducted a full spectral line survey of the 3-13 micron region of two massive protostars, AFGL 2591 and AFGL 2136, for the first time at high spectral resolution.

Humans and songbirds learn their vocalizations early in life by exposure to the vocalizations of adult conspecifics. Often, better learning outcomes are achieved with live, social, tutors than with audio-only exposure to vocalizations.

In today's volatile market environments, companies must be able to continuously innovate. In this context, innovation does not only refer to the development of new products or business models but often also affects the entire organization, which has to transform its structures, processes, and ways of…

In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…

Over the last three decades, the discovery of exoplanets has revealed the boundless variety of worlds beyond our own Solar System⁠. Majority of planetary systems contain short-period planets that are larger than Earth but smaller than Neptune⁠.

Anionic particles play an important role in biological systems where they fulfil many essential functions for cells.

Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

Op 11 november 2021 verdedigde Mariana Gkliati het proefschrift 'Systemic Accountability of the European Border and Coast Guard'. Het promotieonderzoek is begeleid door promotoren prof.dr. P. Rodrigues en prof.dr. L. Besselink (UvA).

Thermodynamics is one of the founding scientific pillars that has helped us better understand heat engines, biology, ecosystems, and even black holes. While it fundamentally describes large systems by examining the bulk behavior of their constituents, it is anchored in the statistical equivalence of…

Metal production is not only energy-intensive and a major source of greenhouse gas (GHG) emissions, but is also associated with other impacts affecting human health and ecosystems.

In the early universe, the dynamics of the Higgs field can give rise to many interesting phenomena.

Samenwerking vormt de kern van ons werk binnen het thema 'Health and well-being in a healthy society'.

Het Expertisebureau D&I werkt nauw samen met de faculteiten van de Universiteit Leiden.

Studying the impact of urbanisation on the respiratory health of past Dutch populations (1200-1850 CE).

Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.

Promotores: P. Stevenhagen, L. van Geemen (Università degli studi di Milano), Co-Supervisor: Ronald M. van Luijk