Mycorrhizas are symbiotic associations between soil fungi and most plant species.

In this thesis,

Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.

In this thesis, I targeted the orchid genus Lepanthes, one of the six genera of angiosperms that surpasses 1,000 species in the Neotropics, as a study model to investigate the evolutionary processes that promoted species diversifications.

Promotor: Prof.dr. P.G.L Klinkhamer, Co-promotor: K. Vrieling

Promotor: C.J. ten Cate

In my research, I used a comparative wood anatomical approach to address wood evolution of the (largely) tropical flowering plant families Apocynaceae and Sapotaceae.

Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.

Dit stappenplan geeft je de nodige hulp en begeleiding bij het indienen van je aanmelding voor de masterspecialisatie Klinische Psychologie aan de Universiteit Leiden.

Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

Science is typically a patchwork of research contributions without much coordination. Especially in clinical trials, the follow-up studies that we do fail to be the most promising.

The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).

Hieronder vind je de antwoorden op een aantal veelgestelde vragen over toelating tot de klinische specialisaties van de Master Psychologie.

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

Explaining treatment response variability between and within patients can support treatment and dosing optimization, to improve treatment of individual patients.

De Universiteit Leiden stimuleert studenten om na hun bacheloropleiding door te gaan met de masteropleiding. Je Leidse bachelordiploma Psychologie geeft je toegang tot de masteropleiding Psychologie in Leiden.

Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.

A neurocognitive investigation of the development of social performance monitoring in youth growing up in stressful versus non-stressful environments

Promotores: J. Jonkers, K.E. de Visser

Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius

Binnen de sectie Gezondheids-, Medische en Neuropsychologie wordt onderwijs verzorgd en onderzoek verricht op verwante deelgebieden van de psychologie: Gezondheids-, Medische en Neuropsychologie.

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…

Het doel van dit onderzoek is om de bijwerkingen tijdens de behandeling met methylfenidaat in kaart te brengen en te onderzoeken hoe kinderen het gebruik van het medicijn (zoals Ritalin, Concerta en Medikinet) ervaren.

This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.

This thesis investigated miniaturized mass spectrometry (MS)-based analytical methods to address challenges in analyzing biomass-restricted biological samples.

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

Atherosclerosis is a progressive disease resulting in the formation of an arterial plaque. Despite lipid lowering, recurrent cardiovascular events remain a risk. While atherosclerosis is primarily lipid-driven, the immune system plays a critical role in the pathophysiology.

Transcutaneous vagus nerve stimulation (tVNS) was tested in chronic worriers. tVNS may reduce spontaneously occurring negative thought intrusions. After a worry induction, there was no longer an effect of tVNS. tVNS did not affect physiological responding to worrying.

We found that, next to the effectiveness of the intervention, it’s also very likely that the intervention is cost-effective compared to attention only.

Tot wel 50% van de mensen met de ziekte van Parkinson ontwikkelt na verloop van tijd cognitieve achteruitgang; deze studie onderzoekt het gebruik van ‘oefeneffecten’ op neuropsychologische tests als een vroege voorspeller van cognitieve achteruitgang.

Seksueel misbruik van kinderen is een veelvoorkomend probleem: wereldwijd wordt ongeveer één op de vijf meisjes en één op de dertien jongens vóór hun achttiende jaar slachtoffer van een vorm van seksueel misbruik. Ondanks de hoge prevalentie zwijgen veel slachtoffers over deze ervaringen en wachten…

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In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.

Structural variants (SVs) are the hidden architecture of the human genome, and are critical for us to understand diseases, evolution, and so on.

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Integratie van MOOC in campus

In het onderzoek “Zwijgen over seksueel misbruik” kijken we naar hoe het gaat met mensen die seksueel misbruik hebben meegemaakt en daar nog nooit over gesproken hebben (m.u.v. eventueel een hulpverlener).

The aims of the project are to: further clarify 'inhibition by safety'; explore and describe all possible sagety factors, with a special focus on the primary human safety source: social connectedness; reviewing prolonged stress responses without stressors.

Optimalisatie, werkingsmechanismen en voorspellers van het resultaat van lichttherapie bij depressie: Een multicenter gerandomiseerde trial

Welke rol spelen ouder-kind interacties bij het ontstaan, in stand houden en de behandeling van depressieve klachten van jongeren?

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