Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.

We present an extensive study of methods for exactly solving stochastic constraint (optimisation) problems (SCPs) in network analysis. These problems are prevalent in science, governance and industry.

Humans can see the world through the eyes of other humans and imagine what they know, want, and intend. This competence is known as Theory of Mind.

In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.

Industrial manufacturing processes, such as the production of steel or the stamping of car body parts, are complex semi-batch processes with many process steps, machine parameters and quality indicators.

With tomography it is possible to reconstruct the interior of an object without destroying.

Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)

Promotor: S.M. Verduyn Lunel, Co-promotor: O. van Gaans

Promotores: Prof.dr. G.A. van der Marel, M. van Heel

We consider the propagation of electrical signals through nerve fibres.

The increasing resistance of pathogenic bacteria to antibiotics necessitates the discovery of new medicines.

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman

Promotor: Prof.dr. T. Schmidt

Promotores: K.J. Batenburg, B. Koren

Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

The aromatic infrared bands (AIBs) seen throughout the interstellar medium (ISM) are generally thought to be carried by polycyclic aromatic hydrocarbons (PAHs) and their nitrogen analogues (PANHs).

Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.

Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma

Promotores: W. Th. F. den Hollander, M.O. Heydenreich

Balsaminaceae is a diverse plant family characterized by a huge floral morphological diversity.

In this Yearbook you will find some fascinating examples of what was done in 2021, not only by ourselves, but also by our international colleagues.

Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.

Promotores: B. van de Water; P. Hogendoorn; J. Bovée Co-Promotor: E.H.J. Danen

Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe

Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.

Promotor: Prof.dr. J.N. Kok, Co-promotor: A.J. Knobbe

Every organisms in the tree of life faces the same challenge: the length of its DNA exceeds the volume of the cell it needs to fit in. Several strategies have evolved to solve this problem, one of them being the expression of proteins that bind and organize the DNA.

Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.

Promotor: K.J. Batenburg

The sequence-dependence of biomolecular interactions involving nucleic acids and proteins is essential for numerous processes inside the cell. Insights into the underlying molecular mechanisms have been obtained using various biochemical and biophysical methods on two different levels — bulk and sin…

Promotor: E.F. Smets Co-promotor: J. Geml

Promotores: J.N. Kok, H.J. Hoogeboom

Complex Organic Molecules (COMs) have been detected in objects across different stages of stellar evolution.

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

Marine sponges are important members of reef ecosystems, as they play ecological roles that are essential for the health of the reef.

Why do black holes emit thermal radiation? And how does a closed quantum system thermalize?

Promotor: B.van de Water, Co-promotor: L.S.Price

The plant hormone auxin plays a central role in the growth and development of plants. Auxin acts in a concentration dependent manner and polar cell-to-cell transport of this hormone determines its distribution in the tissues of plants. This polar auxin transport is mediated by several families of auxin…

In this PhD-thesis several new and existing data science application are described that are particularly focused on applications for tax administrations.

In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.

Where does the urge to collect come from? What are the explicit or underlying reasons for gathering large amount of objects?

Promotor: Prof.dr. E. F. van Dishoeck

The demand for neodymium-iron-boron (NdFeB) magnets is rapidly growing, while the neodymium supply chain is under pressure. Recycling can alleviate these issues. This thesis investigates the potential for deploying novel magnet recycling technologies and their environmental consequences.

Het doel van het RAISE Onderzoek is om te onderzoeken hoe veerkrachtige mensen omgaan met stress. We kijken specifiek naar hoe belangrijke biologische systemen, zoals de HPA-as en het immuunsysteem, samenwerken met de hersenen en de sociale omgeving om veerkrachtig functioneren na moeilijkheden in de…

In this thesis we explore machine and deep learning approaches that address keychallenges in high dimensional problem areas and also in improving accuracy in wellknown problems. In high dimensional contexts, we have focused on computational fluid dynamics (CFD) simulations.

A common method to solve expensive function evaluation problem is using Bayesian Global Optimization, instead of Evolutionary Algorithms.

Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.

Promotor: Prof.dr. E. Smets, M. Stech