1,515 zoekresultaten voor “fundamental right” in de Publieke website
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Surface-structure dependence of water-related adsorbates on platinum
Promotor: M.T.M. Koper, Co-promotor: J.B.F. Juurlink
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Interaction of oxygen and carbon monoxide with Pt(111) at intermediate pressure and temperature: revisiting the fruit fly of surface science
Promotor: M.T.M. Koper, Co-promotors: A.I. Yanson, L.B.F. Juurlink
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Determination of surface formation energies on curved single crystals from STM images
In this thesis, we study different curved single crystals because of the diversity of surface structures across their curvature.
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Design and Synthesis of Click Lipids as Tools to Study Immune Cell Metabolism
This thesis advances our understanding of lipid uptake, a vital first step in lipid metabolism, by developing innovative click chemistry-based tools to study how immune cells internalize lipids.
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Stereoelectronic and conformational effects in oxocarbenium, iminium and iminosugar ammonium ions
Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée
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CellEKT: a chemical proteomics platform to study the kinome
Kinase inhibitors are key therapeutic agents, particularly in oncology, yet their clinical efficacy is often hampered by off-target effects and limited understanding of their cellular target profiles.
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Design and Synthesis of Immunomodulatory Peptide Conjugates
This dissertation explores new chemical strategies for the synthesis of self-adjuvanting peptide conjugates and immunomodulatory ligands aimed at targeted activation of the immune system.
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Kinetic and Non-Kinetic Effects for the Alkaline Oxygen Evolution Reaction on NiFeOOH Electrocatalysts
Green hydrogen is produced via a process called water electrolysis. During electrolysis water is split into oxygen and hydrogen.
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Proton transport through non-covalently functionalized graphene
Single-layer graphene (SLG) has attracted considerable interest as a proton exchange membrane for direct methanol fuel cells (DMFCs), owing to its atomic thickness, mechanical robustness, and unique proton permeability.
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Synthesis, structure and epitope mapping of well-defined Staphylococcus aureus capsular polysaccharides
This dissertation presents the synthesis and evaluation of antibody recognition for various capsular polysaccharide (CP) fragments of Staphylococcus aureus (S. aureus).
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Coupled Electronic and Nuclear Dynamics at Interfaces of Artificial Photosynthesis Devices
Reducing greenhouse gas emissions is one of the most pressing challenges that humanity faces in the coming decades.
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Unravelling Glycosylation Reaction Mechanisms
A key step in the synthesis of oligosaccharides and glycoconjugates is the formation of the glycosidic bond.
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Operando Spectro-electrochemical investigations of Pt and Pt-alloys as Fuel Cell Catalysts
The overall theme of this thesis is to complement the electrochemical data acquired in fuel cell research with in situ X-ray photoelectron spectroscopy (XPS) and soft X-ray absorption spectroscopy (XAS).
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Advances in 2D Material Synthesis, Transfer, and Device Integration
This thesis focuses on developing wafer-scale two-dimensional (2D) materials by combining synthesis, transfer, characterization, and device integration of graphene, hexagonal boron nitride (h-BN), and BN-doped amorphous carbon.
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Benoeming Dr. Leila Akkari tot bijzonder hoogleraar aan de Universiteit Leiden
Per 15 december 2025 is Dr. Leila Akkari benoemd tot bijzonder hoogleraar bij het Leiden Institute of Chemistry (LIC). Haar leerstoel met de opdracht Kanker-Immuun Interacties is gevestigd door het Nederlands Kankerinstituut (NKI), alwaar Dr. Akkari werkzaam is als onderzoeker.
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Willemien den Ouden spreekt met Kamerleden over het uitdaagrecht
Op woensdag 3 april jl. organiseerde de vaste Kamercommissie voor Binnenlandse Zaken een rondetafelgesprek over het uitdaagrecht (ook wel het 'Right to Challenge' genoemd). Dit uitdaagrecht houdt in dat burgers het recht zouden krijgen om een gemeentelijke taak zelf uit te voeren als zij dat beter k…
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Esmée Driessen wint scriptieprijs UM
Esmée Driessen, onderzoeks- en onderwijsmedewerkster van de afdeling Staats- en bestuursrecht aan de universiteit Leiden, heeft de facultaire scriptieprijs van de Universiteit van Maastricht gewonnen. Ieder jaar rijkt de Stichting Wetenschapsbeoefening UM prijzen uit aan de studenten die de beste scriptie…
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Joeri ReindersFaculteit Governance and Global Affairs
j.b.reinders@luc.leidenuniv.nl | +31 70 800 9500
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Darinka Piqani over transparantie en het recht op informatie binnen Europees Recht
Van 16 tot 20 januari 2023 was Darinka Piqani op bezoek bij de Rechtenfaculteit van de Universiteit van Tirana (Albanië). Zij gaf een serie colleges over transparantie en het recht op informatie binnen het Europees Recht. Deze colleges werden georganiseerd als onderdeel van de Research Expertise from…
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Onderzoek
De Faculteit der Rechtsgeleerdheid verricht hoogwaardig onderzoek naar acht onderzoeksprogramma's.
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Activity-Based Proteasome Profiling
Promotor: Prof.dr. H.S. Overkleeft
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Upconverting nanovesicles for the activation of ruthenium anti-cancer prodrugs with red light
Promotor: E. Bouwman, Co-promotor: S. Bonnet
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Dynamic organization of bacterial chromatin by DNA bridging proteins
Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.
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Mononuclear spin-transition materials based on the bapbpy scaffold
Promotor: Prof.dr. E. Bouwman, Co-Promotor: S. Bonnet
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Biophysical characterization of membrane protein-small molecule interactions
Promotor: Prof.dr. M. Ubbink
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Stable single molecules for quantum optics and all-optical switches
Promotor: Prof.dr. M.A.G.J. Orrit
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Algorithms for finite rings
Promotores: H.W. Lenstra, K. Belabas (University of Bordeaux)
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Inhibitor discovery of phospholipases and N-acyltransferases
In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.
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Leiden-Benghazi onderzoek naar conflicten rond onroerend goed in Libië
Dr. Suliman Ibrahim van het Van Vollenhoven Instituut doet in opdracht van het Ministerie van Buitenlandse Zaken onderzoek naar problemen rond onroerend goed in Libië.
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Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
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Fundamenteel onderzoek: Onderliggende mechanisme van ziekte en welzijn
Om de juiste klinische beslissingen te nemen of effectieve diagnostische testen en behandelingen te kunnen ontwikkelen, is het belangrijk om de onderliggende mechanismen van een aandoening of een bepaald gedrag te begrijpen.
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Deciphering the complex paramagnetic NMR spectra of small laccase
Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.
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Synthetic, Physical and Computational Chemistry of Propeller-shaped Polycyclic Aromatic Hydrocarbons
This thesis systematically studies the physicochemical properties of non-planar, propeller-shaped, polycyclic aromatic hydrocarbons. The synthesis of several so-called propellerenes is described on a gram scale, using optimized procedures aimed at using less hazardous reagents and reducing the amount…
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Linking the gene regulatory network with the functional physical structure of whole-genome engineered Arabidopsis mutants : an HR-MAS NMR-based
Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.
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Ab initio molecular dynamics calculations on reactions of molecules with metal surfaces
Promotor: Prof.dr. G.J. Kroes
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Synthesis of oligosaccharide libraries from GBS capsular polysaccharides for structure-based selection of vaccine candidates
Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.
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Photocatalytic redox reactions at the surface of liposomes
Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet
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Reactivity and Selectivity in Glycosylation Reactions
The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.
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Monitoring Alzheimer's disease in transgenic mice with ultra high field magnetic resonance imaging
Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia
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Mining the kinematics of discs to hunt for planets in formation
Detecting planets during their formation stages is crucial for understanding the history and diversity of fully developed planetary systems like our own. However, observing young planets directly is challenging because they are often deeply embedded within their host protoplanetary discs, rich in gas…
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A chemical biology approach for targeting of ligand-drug conjugates
Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot
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Microneedle-mediated vaccine delivery
Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot
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The Diving Dutchman: het marien-gravimetrisch onderzoek van F.A. Vening Meinesz (1887-1966)
Promotores: Prof.dr. F. van Lunteren, Prof.dr. F.S. Gaastra
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Chemical tools to monitor and control proteasome activities
Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea
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The heart of oxygenic photosynthesis illuminated
Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia
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Towards photo-CIDNP MAS NMR as a generally applicable enhancement method
Promotores: Prof.dr. H.J.M. de Groot, Prof.dr. J. Matysik (Universitaet Leipzig)
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Taking control of charge transfer: strategic design for solar cells
Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda
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Innovative diagnostics and treatments
Hoe meer we leren over een (neuro-)psychologische of lichamelijke aandoening en de hieraan gerelateerde gedragsfactoren, hoe beter we deze niet alleen kunnen signaleren, maar ook behandelen. Het is dus belangrijk dat recente inzichten over (neuro-)psychologische problemen en daaraan gerelateerde gedragsfactoren…
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Synthesis of phosphodiester-containing bacterial cell wall components: teichoic acids, capsular polysaccharides and phosphatidyl glycerol analogues
Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée
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Microscopy and Spectroscopy on Model Catalysts in Gas Environments
In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.