869 zoekresultaten voor “time microenvironment” in de Publieke website
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mechanistic studies revealing a protective role in the plaque microenvironment
Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.
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Tailor-Made: Leveraging the Tumor Microenvironment to Boost Treatment for Advanced Liver Cancer
Promotie
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Latency, Energy, and Schedulability of Real-Time Embedded Systems
Systems are called real-time systems, if the correctness of the system does not only depend on the correctness of the system output but also on whether the output is delivered on time.
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It's about time
This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.
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Real-time tomographic reconstruction
With tomography it is possible to reconstruct the interior of an object without destroying.
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Data-driven Predictive Maintenance and Time-Series Applications
Predictive maintenance (PdM) is a maintenance policy that uses the past, current, and prognosticated health condition of an asset to predict when timely maintenance should occur.
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Combining monitoring with run-time assertion checking
Promotor: F.S. de Boer, Co-promotor: M.M. Bonsangue
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Methods and Tools for Mining Multivariate Time Series
Mining time series is a machine learning subfield that focuses on a particular data structure, where variables are measured over (short or long) periods of time.
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SAILS Lunch Time-seminars
Ontdek de kracht van interdisciplinair AI-onderzoek bij het SAILS-initiatief van de Universiteit Leiden via dit tweewekelijkse seminar. Het SAILS-netwerk van AI-experts bestrijkt alle zeven faculteiten: Rechtsgeleerdheid, Wiskunde en Natuurwetenschappen, Archeologie, Sociale Wetenschappen, Geesteswetenschappen,…
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Real-time foresight: preparedness for dynamic innovation networks
Promotor: H.J. van den Herik, B.R. Katzy, Co-promotor: K. Sailer
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Metabolomic characteristics of Catharanthus roseus plants in time and space
Promotor: R. Verpoorte, Co-promotores: Y.H.Choi, N.R. Mustafa
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Regulating Working Conditions in Times of Globalization
Op 28 juni 2018 verdedigde Qiuyin Hu zijn proefschrift 'Regulating Working Conditions in Times of Globalization'. Het promotieonderzoek is begeleid door promotoren prof.dr. G.J.J. Heerma van Voss en prof. dr. B. Barentsen.
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Large Time Behaviour of Neutral Delay Systems
Promotor: S.M. Verduyn Lunel
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The holographic glass bead game: from superconductivity to time machines
Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm
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Incubation and latency time estimation for SARS-CoV-2
De incubatietijd (van infectie tot de eerste symptomen) en latente periode (van infectie tot de start van besmettelijkheid) zijn cruciaal voor het informeren van controle maatregelen aan het begin van een infectieziektenuitbraak. Een voorbeeld is de duur van quarantaine voor potentieel geïnfecteerden,…
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Measuring gold molecular gas across cosmic time
Tracing the evolution of the molecular gas content in galaxies is critical for a complete understanding of galaxy formation and evolution, as it provides the direct fuel for star formation. Studies of high-redshift (z>1) molecular gas reservoirs, most commonly traced by carbon monoxide (CO), have seen…
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Drug-target residence time: a case for the adenosine A1 and A2A receptors
Promotor: A.P.IJzerman, Co-Promotor: L.H. Heitman
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Automated machine learning for dynamic energy management using time-series data
Time-series forecasting through modelling sequences of temporally dependent observations has many industrial and scientific applications. While machine learning models have been widely used to create time-series forecasting models, creating efficient and performant time-series forecasting models is…
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Statistical modelling of time-varying covariates for survival data
This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.
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The CIA and Time Magazine: Journalistic Ethics and Newsroom Dissent
Simon Willmetts levert bewijs voor een systematisch beleid van directe samenspanning tussen Time Inc. en de CIA
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Resolving the building blocks of galaxies in space and time
We investigate the buildup of galaxies from various vantage points. The first two chapters focus on the stellar content of galaxies, especially the distribution of stellar masses at birth and potential variations therein in various galactic environments.
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Time Domain Imaging of Transient and Variable Radio Sources
This thesis focuses on the study of transient and variable radio sources in the universe.
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Improved hard real-time scheduling and transformations for embedded Streaming Applications
This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.
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Dynamic real-time substrate feed optimization of anaerobic co-digestion plants
Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska
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Securing the integrity of financial markets in times of crisis
Het Hazelhoff Centre for Financial Law onderzoeksprogramma voor 2020-20203 draait om de integriteit van financiële markten in tijden van crisis en de mogelijke manieren om deze integriteit te bewerkstelligen.
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Distance-based analysis of dynamical systems and time series by optimal transport
Promotor: S.M. Verduyn Lunel
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Central banking in difficult times
Nout Wellink sprak over de rol van de centrale bank in het huidige roerige financiële klimaat. Daarbij gaat hij ook in op de gewijzigde kapitaaleisen die voor banken gelden.
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Biophysical studies of intracellular and cellular motility
This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.
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On hard real-time scheduling of cyclo-static dataflow and its application in system-level design
Promoter: Ed F. Deprettere, Co-promoter: Todor P. Stefanov
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Plant occurrence in space and time: the importance of land use, habitat structure, and pollination mode
Plant diversity is essential for us and our planet as it sustains the stability of our ecosystems, provides vital materials and food to us and supports many ecosystem services.
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The distribution of stellar mass in galaxy clusters over cosmic time
Promotor: Prof.dr. K.H. Kuijken, Co-Promotor: H.Hoekstra
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A time-space translation mechanism for patterning the vertebrate anteroposterior axis
My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.
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Mechanistic modelling of drug target binding kinetics as determinant of the time course of drug action in vivo
Drug-target binding kinetics determine the time course of the central event in pharmacotherapy: Drug-target interaction.
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Web Privacy Measurement in Real-Time Bidding Systems, A Graph- Based Approach to RTB system classification
Op 29 januari 2019 verdedigde Robbert van Eijk proefschrift 'Web Privacy Measurement in Real-Time Bidding Systems, A Graph- Based Approach to RTB system classification'. Het promotieonderzoek is begeleid door promotor prof. dr. H.J. van den Herik.
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galaxy clusters: probing magnetism and particle acceleration over cosmic time
In this thesis, I studied the origin and evolution of the non-thermal radiation in merging galaxy clusters.
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Time is of the essence: investigating kinetic interactions between drug, endogenous neuropeptides and receptor
Promotor: A.P. IJzerman Co-promotor: L.H. Heitman
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SAPPAO - Optimizing the flight times of airplanes using data science
Met het SAPPAO-project willen we de voorspelling van geplande vluchten nauwkeuriger en betrouwbaarder maken. De volledige naam van het project is ‘A Systems Approach towards Data Mining and Prediction in Airlines Operations’.
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Constructing an ‘emotional community’ in times of crisis: the EU’s response to Russia’s invasion of Ukraine in 2022
Emoties spelen een cruciale rol in de EU-politiek. Dit artikel onderzoekt hoe emoties de EU-reactie op internationale crises door normovertredingen beïnvloeden.
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from them': Holding space for solidarity otherwise and the city in times of Covid‐19
In dit artikel onderzoeken de onderzoekers hoe solidariteit begrepen kan worden, rekening houdend met de diversiteit van verhalen, ruimtes, praktijken, lichamen en tijdsperiodes in een stad.
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Mechanisms of Ewing sarcoma metastasis
Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska
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Dissecting the immune microenvironment of breast cancer
Promotie
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Pedro Russo over gendervooroordelen op Times Higher Education
Drie van de vier wetenschappers afgebeeld in basisschoolboeken zijn mannen, toont een recente studie door Sterrewachtwetenschapper Pedro Russo. In een interview legt hij uit hoe dit de latere loopbaan van kinderen kan beïnvloeden.
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Zebrafish xenograft model: identification of novel mechanisms driving prostate cancer metastasis
Prostate cancer (PCa) is one of the most prevalent cancer in males.
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Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin
Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri
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Microphysiological liver systems for in vitro modeling and industry implementation
This thesis tackles the difficulty of predicting the liver’s clinical response to novel therapies, a challenge arising from interspecies differences and limitations of existing in vitro models.
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Mathieu CherpitelWiskunde en Natuurwetenschappen
m.j.l.cherpitel@liacs.leidenuniv.nl | 071 5272727
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Universiteit Leiden 67e in Times Higher Education Ranking
In de Times Higher Education Ranking gepubliceerd op 30 september, staat de Universiteit Leiden als vijfde Nederlandse Universiteit op plaats 67. Vorig jaar op 64, daarmee is de universiteit licht gedaald. Vanwege veranderingen in de systematiek zegt dat echter niet zoveel.
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Algorithms for finite rings
Promotores: H.W. Lenstra, K. Belabas (University of Bordeaux)
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TGF-β and extracellular vesicles in the tumor microenvironment
Promotie