We strive to address the challenge of constructing a modeling language to write software which can take advantage of recent hardware developments (multicore, cloud) without compromising in its abstraction levels.

One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…

The overarching goal of this PhD thesis is to investigate the taxonomic and functional diversity of yeasts in the wheat phyllosphere and their interactions with the mycotoxigenic fungal pathogen Fusarium graminearum.

Het project is gefinancierd door SoFoKleS en mede mogelijk gemaakt door steun vanuit en samenwerking met de Universiteit Utrecht en verschillende partijen binnen de Universiteit Leiden.

In deze opleiding verbreed je je kennis over de veiligheid en kwaliteitscontrole bij het produceren van medicinale producten en ben je goed voorbereid op een carrière in Quality Assurance en Quality Control in de biotechnologische en farmaceutische industrie.

We gingen het water op! Op zaterdag 30 augustus 2025 gingen onze studenten samen met Plastic Soup Surfer Merijn Tinga de Leidse grachten op om te suppen én afval uit het water te vissen.

Antibiotica, bacteriën en resistentie zijn zeer geschikte onderwerpen voor een profielwerkstuk. Hier vind je alvast een aantal handige links.

Promotor: A. Doelman, Co-promotor: J.D.M. Rademacher

Op 16 juni 2020 verdedigde Andrea Varga haar proefschrift 'Establishing State Responsibility in the Absence of Effective Government'. Het promotieonderzoek is begeleid door promotoren prof. dr. N.J. Schrijver en prof. dr. F. Baetens (University of Oslo).

Synthetic microswimmers take an important place within the interdisciplinary field of active soft matter.

Promotores: C.A.M.J.J. van den Hondel, V. Meyer, Co-promotor: A.F.J. Ram

The emergence of complex diseases resulting from abnormal cell-cell signaling and the spread of infectious diseases caused by pathogens are significant threats to humanity. Unraveling the dynamic mechanisms underlying cell-cell signaling and infectious disease spreading is crucial for effective disease…

Promotor: G.R. de Snoo Co-promotor: C.J.M. Musters

Het belangrijkste doel van dit onderzoek is om de steden van het Romeinse Nabije Oosten in de keizertijd in kaart te brengen, met een focus op locatie, stadsgrootte en stedelijke kenmerken, om de vorm van het stedelijke systeem en de niveaus van integratie te bestuderen.

Promotie

This dissertation aims to advance understanding of amoeboid single cell migration under the influence of changing physicochemical environmental properties. The particular focus is on the relatively unknown influence of differing physical properties in the extracellular environment, such as the migratory…

The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…

With an emphasis on developing novel miktoarm star polymers termed PeptoMiktoStars, this thesis leverages asymmetric polymeric polypept(o)ide frameworks to advance their effectiveness in delivering hydrophobic drugs and nucleic acids.

Promotor: K.H. Kuijken

Promotor: J.M. Memelink

A structural investigation of coiled coil peptides used as membrane fusogens, mimicing naturally occuring coiled-coil fusion proteins. Synthetic modifications have been made to alter lipid attachment, secondary structure and to insert photoactive azobenzene moieties for active control over coiled coil…

This thesis describes the importance of being able to control the selectivity of potential drug candidates.

Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.

This thesis focuses on two processes involved in fighting infections: metabolism and immune cell motility and navigation.

Promotor: Prof.dr.ir. J.G.E.M. Fraaije, Co-promotor: A. Kros

The marine shipping industry is one of the strongest emitters of nitrogen oxides (NOx), a pollutant detrimental to ecology and human health. Over the last 20 years, the pollution produced by power plants, the industry sector, and cars has been decreasing.

Online scriptiebegeleiding

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Veel mensen houden van muziek. Maar waarom precies – dat weten we nog niet. Ook weten we weinig over individuele verschillen in muziekbeleving. Rebecca Schaefer gaat hiernaar onderzoek in aanloop naar het SNAAR-festival in Utrecht. Op een unieke manier: mbo-studenten worden de onderzoekers.

Wij zijn aangesloten bij Una Europa: een alliantie van elf vooraanstaande Europese universiteiten.

De leerstoel Democratische Vertegenwoordiging in het Koninkrijk richt zich op de politieke relaties tussen Europees Nederland en de zes Caribische eilanden in het Koninkrijk; de zogenaamde Koninkrijksrelaties. In het kader van de leerstoel doet Prof. dr. Wouter Veenendaal onderzoek naar de kwaliteit…

Promotores: R. Cramer, A.K. Lenstra, Co-Promotor: B.M.M. de Weger

This PhD-thesis presents a study on micron-sized particles, so-called colloids. By controlling the chemical and physical properties of these particles, such as the interparticle interaction and the particles’ shape, colloids can act as building blocks that self-assembly into larger structures.

The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)

The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

Mechanical metamaterials are carefully engineered materials whose properties are controlled by their structure, not by their composition, which allows using metamaterials to study and control physical effects in detail⁠.

Growth hormone profiles are pulsatile and highly variable between individuals, limiting the implementation of mathemathical models to quantify an individual's secretion.

In november 2020 is het Engelstalige boek ‘Financial Collateral; Law and Practice’ verschenen. Het boek is gepubliceerd door Oxford University Press en geredigeerd en geschreven door professor Matthias Haentjens. Voorts hebben meegeschreven Anthony Zacaroli (High Court, Chancery Division), Yael Diamant…

Promotor: G.P. van Wezel

This thesis describes how to scale down concepts of macroscopic mechanical metamaterials to the thermal scale using a system of flexibly-linked colloids.

During post-embryonic development into adults, animals face an environment that fluctuates constantly. For example, in nutrient availability, temperature, and osmolarity (e.g., salt concentration).

Promotores: W. Th. F. den Hollander, M.O. Heydenreich

Promotor: B. van de Water

The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.