The main topic of this PhD thesis is the Arakelov ray class group of a number field, an algebraic object that contains both the ideal class group structure and the unit group structure.

A Josephson junction is a device where a thin insulating barrier or a nanostructure is placed between two superconducting leads. Such a junction is essential to superconducting qubits that store quantum information due to its anharmonic spectrum.

How are new drugs developed? This question is central to the Minor Modern Drug Discovery (MDD), which covers the entire trajectory from disease to drug molecule and vice versa. The various research groups involved offer a complementary and interdisciplinary perspective by connecting the diverse subjects…

Onderzoek naar taal levert een schat aan informatie over de mens: onze geschiedenis, verklaring van cultuurverschillen tot de manier waarop we leren. De universiteit deelt haar kennis en passie over het onderwerp op nieuwe manieren, via de MOOC ‘Miracles of Human Languages’ en het webdossier Taaldiv…

In this thesis, I studied the origin and evolution of the non-thermal radiation in merging galaxy clusters.

My PhD research is devoted to studies of the conjectural cluster-algebraic symmetry in the theory of topological string, which is the simplest, however already non-trivial sector in the theory of string.

This dissertation contains four works during my PhD. Different biomaterials have been designed based on coiled-coil peptides. These biomaterials have a range of applications, inclusing drug delivery, cell sorting to cell-cell fusion.

This thesis consists of three papers that are centered around the common theme of Hausdorff uo-Lebesgue topologies and convergence structures on vector lattices and on vector lattices and vector lattice algebras of order bounded operators.

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: G.J. Herczeg

Promotie

This thesis is about augmented reality (AR). AR is commonly considered a technology that integrates virtual images into a user’s view of the real world.

The origin and evolution of galaxies are closely linked to many different physical phenomena.

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

A plasma is an ionized gas with very low electrical resistivity. As such, magnetic field lines are 'frozen in' and move with the fluid. Magnetic field lines that are linked, knotted and tangled, cannot be undone by the fluid motions.

Dissochaeta Blume (Melastomataceae, tribe Dissochaeteae) is well-known as a scrambling plant genus found in Southeast Asia, where it is an inhabitant of the tropical rainforests or evergreen forests.

In this PhD study, I aim to deepen our understanding of the influence of major mycorrhizal types, namely arbuscular mycorrhizae (AM) and ectomycorrhizae (EM), on the global soil carbon cycle and their potential distribution changes under future environmental shifts.

This thesis studies operator-algebraic aspects of subproduct systems, a generalization of product systems of Hilbert spaces.

The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.

Promotor: S.J. Edixhoven

Promotor: Prof.dr. P. Stevenhagen, Jan-Hendrik Evertse, Co-promotor: Pascal Autissier

In this thesis we have discussed several parameters that affect the electrochemical conversion of enviromentaly harmful molecules such as nitrates and carbon dioxide to more valuable and less deleterious compounds, in order to cast light onto the mechanism of the reaction to achieve an efficient and…

Promotor: K.H. Kuijken

The main objective of this thesis was to develop clinically relevant survival models for patients with high-grade soft tissue sarcoma of the extremities, in particular the development and validation of prediction models for use in clinical practice.

The main object of study in this thesis is an Arakelov inequalitywhich bounds the degree of an invertible subsheaf of the direct image ofthe pluricanonical relative sheaf of a semistable family of curves.

In this thesis, we developed new ways to use a technique called electroextraction (EE) to extract charged molecules from one liquid into another using an electric field.

In this thesis, we have studied cell images from two types of cells, including pollen grains and the immune cells, neutrophils. These images are captured using a bright field microscope and a confocal microscope.

Promotor: F. Arbab, R. De Nicola, Co-Promotor: M. Tribastone

Promotores: Prof.dr. M. Franx, Prof.dr. P.G. van Dokkum (Yale University)

Metabolomics is a powerful tool that can provide a comprehensive insight into the complexity of human biology and the pathophysiology of diseases. By analyzing the metabolome, which refers to the complete set of small (endogenous) molecules (with a mass <1500 Da) present within a given biological system,…

Cardiovascular diseases are still a major concern for the global health.

Data Science (DS) and Artificial Intelligence (AI) are omni-present and have the potential to be incorporated in various fields. However, in order to live up to this expectation, a good understanding of the techniques, their implications and limitations is required. In this minor you develop insights…

De nominaties voor de jaarlijkse Prof. dr. J.Th.J. van den Berg-prijs voor de beste bachelorscriptie van de opleiding Politicologie/Internationale Betrekkingen en Organisaties zijn bekend. Het betreft elf scripties over diverse onderwerpen, van bootvluchtelingen tot kiesgedrag, en van democratie tot…

Human language is constantly evolving with its linguistic structure being shaped by language users at both individual and population levels. Focusing on the interplay between processes of language acquisition and communicative need in shaping human languages, this thesis introduces a novel computational…

Dankzij een succesvolle crowdfundingscampagne wordt er in het najaar een nieuwe module toegevoegd aan de vervolgsessie van de succesvolle Leidse Massive Online Open Course (MOOC) 'the Miracles of Human Language'; an Introduction to Linguistics. Ruim 240 donateurs hebben het doelbedrag van 10.000 euro…

Misha Plagis, universitair docent aan het Grotius Centre of Public International Law, schreef samen met Dr. Nicole De Silva (Concordia Universiteit) een paper over NGO's, internationale rechtbanken en het verzet van staten tegen de verantwoordingsplicht inzake mensenrechten bij het Afrikaanse Hof voor…

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Promotie

Op 2 juni heeft Mariana Gkliati deelgenomen aan het debat ‘Europe on Trial' in De Balie.

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.

The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…

Promotor: M.T.M. Koper, Co-promotor: L. Juurlink

A large diversity of exoplanetary systems has been found, but it is still unclear what drives this diversity.

Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…

In this thesis, we use low-frequency and high-frequency radio observations to address the following questions regarding quasars: is the radio loud/quiet quasar dichotomy real?