Control of infectious diseases poses continuous challenges for human health.

Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.

This dissertation presents new cryptographic protocols, which can be divided into two families.

This thesis mainly extends the theory of positive operators on Riesz spaces to a setting of pre-Riesz spaces.

This thesis presents pioneering work on the panchromatic emission of some of the most luminous galaxies in the early Universe: star forming galaxies and active galactic nuclei.

Promotoren: R. Tijdeman, A.K. Lenstra, Co-promotor: H.J.J. te Riele

Promotor: M.K. Richardson, Co-Promotor: F. Witte

Nowadays, it is well known that hydrogen and helium (and small traces of lithium and beryllium) were created shortly after the Big Bang, while the heavier elements are created in the cores of stars at different evolutionary stages. When these stars explode as supernovae, they expel metals synthesised…

Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)

Regeneration is the ability of an organism to restore damaged or lost tissue with a functional replacement, and without scarring. Many lizards can regenerate their tails.

This thesis describes the functional analysis of the Arabidopsis AHL15 gene.

We consider the propagation of electrical signals through nerve fibres.

Promotores: J. Jonkers, K.E. de Visser

The unit residue group, to which the present thesis is devoted, is defined using the norm-residue symbol, which Hilbert introduced into algebraic number theory in 1897.

Promotor: Prof.dr. P. Stevenhagen

Of all the mass in our Universe, 80% is thought to consist of a hypothetical and invisible substance called dark matter (DM).

All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).

LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.

Promotor: Prof.dr. J. Kuiper

The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.

Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

The marine shipping industry is one of the strongest emitters of nitrogen oxides (NOx), a pollutant detrimental to ecology and human health. Over the last 20 years, the pollution produced by power plants, the industry sector, and cars has been decreasing.

Promotor: A. Kros

Artful Mathematics: The Heritage of M. C. Escher

The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.

Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez.

Where does the urge to collect come from? What are the explicit or underlying reasons for gathering large amount of objects?

A remarkable population of short period transiting rocky exoplanets with equilibrium temperatures on the order of 2,000 K has recently been discovered.

Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…

This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.

The overarching goal of this thesis is to set the foundations, but also make the first essential steps towards establishing a comprehensive, mesoscopic, hydrodynamic theory of epithelial tissues. The stage is set by an exhaustive study of topological defects in passive p-atic liquid crystals, singularities…

Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.

This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.

Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.

Technologies that help to enhance our educational environments can be found everywhere.

Promotor: Bas Edixhoven, Promotor: Qing Liu

Promotor: Prof.dr. P.C. van Welzen

This thesis describes the Multi-site All-Sky CAmeRA (MASCARA), which consists of two small robotic telescope designed to detect exoplanets around the brightest stars in the sky.

Systems are called real-time systems, if the correctness of the system does not only depend on the correctness of the system output but also on whether the output is delivered on time.

Promotores: W. Jiskoot, F. Ossendorp

Taalstudenten in het hoger onderwijs voeren steeds vaker zelfgestuurd leren buiten de klas uit, gefaciliteerd door mobiele technologie. Dit project heeft tot doel te onderzoeken hoe studenten mobiele technologie gebruiken voor hun zelfgestuurd leren van talen en en welke factoren hun zelfgestuurd leren…

Reconstructie van de taalgeschiedenis en prehistorie in de context van de Indo-Europese taalfamilie.

De eenjarige master Linguistics van de Universiteit Leiden combineert de expertise van vooraanstaande wetenschappers met een flexibel programma.

Niet altijd werd in Japan Japans gesproken. Wetenschappers verbinden de komst van de taal naar Japan met de migratie van boeren rond 400 v. Christus. Taalkundige Elisabeth de Boer gaat met een ERC Starting Grant onderzoek doen naar de verdere verspreiding van de taal in Japan.

Learning a programming language is challenging. Even one of the first –but crucial– concepts to learn, variables, is hard to grasp. Variables can represent different roles and functions within a code and need to be named appropriately to support code comprehension and debugging.

Hoe gebruiken moslimautoriteiten en schrijvers het Russisch om islamitische inhoud over te brengen en leidt dit tot een specifiek “islamitisch sociolect” van de Russische taal?

Dit project combineert een uitgebreide nieuwe open database over taalkundige distributies, ruimtelijke modellering en areale taalkunde om de rollen van sociale en omgevingsfactoren bij het ontstaan van taalkundige diversiteitspatronen in Zuid-Amerika te ontrafelen.

Stagemogelijkheden en opdrachten voor studenten

Aan de hand van een verzameling tekstuele, literaire en andere bronnen wordt nieuw licht geworpen op de leeftijd waarop vrouwen in de middeleeuwen bevielen.

Laat je op deze pagina inspireren door best practices van onderwijsvernieuwende voorbeelden die in ons onderwijs invulling geven aan de ambitie Internationalisering en diversiteit.