Bij sommige jongeren met suïcidale gedachten en gedragingen is er een subtiel maar significant verschil in de hersenstructuur, zo blijkt uit onderzoek. 'Het resultaat vertelt wellicht meer over de mechanismen bij suïcidaal gedrag in een specifieke subgroep', zeggen postdoctoraal onderzoeker Laura van…

Public Administration is a major refereed journal publishing articles on public administration, public policy and public management.

In deep reinforcement learning, searching and learning techniques are two important components. They can be used independently and in combination to deal with different problems in AI, and have achieved impressive results in game playing and robotics. These results have inspired research into artificial…

How can we broaden youth participation in STEM Learning

Workshop

De onderzoeksgroep Oorlog, Vrede en Rechtvaardigheid (WPJ) richt zich op de complexe vraagstukken van mondiale conflicten, vrede en rechtvaardigheid, waarbij onderwijskwaliteit een kernfunctie is. Theorie en praktijk komen hier samen, wat een dynamische leeromgeving creëert voor zowel stafleden als…

Promotor: Prof.dr. T. Schmidt, Co-Promotor: S.J.T. van Noort

Op 23 februari 2022 verdedigde Cale Davis het proefschrift 'Prosecutorial Discretion in International Criminal Justice'. Het promotieonderzoek is begeleid door prof.dr. C. Stahn en dr. J.C. Powderly.

Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm

Promotores: J. Kok, M. Chaudron (Chalmers University)

Promotor: A. Achúcarro, Co-Promotor: J.W. van Holten

In his dissertation Michiel Hooykaas outlines the results of six empirical research projects focused at biodiversity awareness in the Netherlands, specifically people’s knowledge about animals.

Promotor: M. Franx, Co-Promotor: I.F. Labbé

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

From surface science towards industrial practice using high-pressure scanning tunneling microscopy.

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet

In het academisch jaar 2023-2024 biedt het interdisciplinaire onderzoeksprogramma Sociale Veerkracht en Veiligheid vier vakken aan voor studenten die beginnen met het derde jaar van hun bachelor. Deze vakken zijn te volgen binnen de ruimte voor keuzevakken. Je kunt de vakken afzonderlijk als keuzevak…

The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

The research provides insight into disease behavior in both rural and semi-urban areas in Serengeti in Tanzania.

Cryptanalist Marc Stevens van het Centrum Wiskunde & Informatica (CWI) in Amsterdam, bekend van zijn 'kraak' van de MD5 hash-functie voor https-beveiliging in 2008, heeft deze week het recente Flame-virus geanalyseerd. Hij ontdekte dat voor deze spy malware een compleet nieuwe, tot nu toe onbekende…

De Engelstalige, interdisciplinaire minor Violence Studies onderzoekt allerlei facetten van interpersoonlijk geweld. Is de minor iets voor elke Leidse student? Deze twee 'collega's zijn ervan overtuigd.

De komende tijd organiseren we verschillende evenementen om jou kennis te laten maken met de opleiding en je toekomstige medestudenten.

Afgestudeerden van de bachelor Security Studies zijn zeer gewild op de arbeidsmarkt dankzij hun uitgebreide kennis van wereldwijde veiligheidskwesties, academische en professionele vaardigheden en de huidige en toekomstige relevantie van het veiligheidsdomein.

Neuraminidases are enzymes that cleave glycosidic linkages of sialic acid. These enzymes are involved in influenza infections as well as in many cellular processes in mammals and micro-organisms.

The main topic of this PhD thesis is the Arakelov ray class group of a number field, an algebraic object that contains both the ideal class group structure and the unit group structure.

n this thesis we study curves. In the first half, we study moduli spaces of curves and Gromov-Witten invariants, certain kinds of curves counts. We employ logarithmic geometry for this.

Kinase inhibitors are key therapeutic agents, particularly in oncology, yet their clinical efficacy is often hampered by off-target effects and limited understanding of their cellular target profiles.

Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers

Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.

The aromatic infrared bands (AIBs) seen throughout the interstellar medium (ISM) are generally thought to be carried by polycyclic aromatic hydrocarbons (PAHs) and their nitrogen analogues (PANHs).

Promotor: W.T. de Groot

In today's volatile market environments, companies must be able to continuously innovate. In this context, innovation does not only refer to the development of new products or business models but often also affects the entire organization, which has to transform its structures, processes, and ways of…

Monoacylglycerol lipase (MAGL) is the principal enzyme responsible for hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-AG). MAGL inhibition provides several potential therapeutic opportunities, including anti-nociceptive, anti-inflammatory and anti-cancer activity.

Promotor: Prof.dr. J.N. Kok, Co-Promotor: W.A. Kosters

This thesis discusses several questions regarding the double ramification cycle as a Chow class on the moduli space of stable n-pointed genus g curves using tools from so-called logarithmic geometry.

A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

Promotor: P.D. Grünwald

Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.

We present an extensive study of methods for exactly solving stochastic constraint (optimisation) problems (SCPs) in network analysis. These problems are prevalent in science, governance and industry.

Streptomyces bacteria are a valuable source of natural products, many of which are used in the clinic or in biotechnology.

Promotores: Prof.dr. G. Miley & Prof.dr. J.M. van den Broek

Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

A century ago, it was unclear whether the stars in the sky were clustered in groups, or widely spread in the universe.

Breast cancer is the most common cancer in women worldwide. Metastasis, the process by which cancer cells spread to other parts of the body, makes treatments less effective. It is important to unravel the mechanism of metastasis.

Promotores: F.H. van Lunteren, F.P. Israel