The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.

Workshop

Promotors: Prof.dr. P.J. Punt, Prof.dr. C.A.M.J.J. van den Hondel

How should jurisdictions, both on the national and on the supra-national level, handle the interaction between public and private law where it regards the regulation of financial markets?

Catharanthus roseus (Madagascar periwinkle) produces valuable monoterpenoid indole alkaloids (MIAs) such as vincristine and vinblastine, crucial for cancer treatment.

Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.

Are you planning to conduct clinical research in the Netherlands? In this online course, you are introduced to legislation and procedures on clinical research in the Netherlands. It will help you prepare and submit your research file efficiently. The first three themes ‘The Dutch Review System’ , ‘The…

Dit boek neemt je stapsgewijs mee in het schrijven van een scriptie, met (voornamelijk) een focus op experimenteel onderzoek, dat het meest veel voorkomt. Door de stappen van experimenteel onderzoek in chronologische volgorde op te splitsen en bij elke stap tips te geven, hopen de auteurs enig houvast…

Promotor: P.M. Brakefield

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

Promotie

Promotie

Metastasis is responsible for over 90% of cancer-related deaths and arises from the ability of a small subset of tumor cells to detach from the primary tumor, overcome multiple biochemical and mechanical barriers, disseminate through the body, and colonize distant organs.

This thesis introduces a relational interaction model and a practical tool for describing, visualising and generating interactive dialogues.

Plants, are sessile organisms, have developed strategies to adapt to changes in their environment, in part by altering their growth and development.

Kinase inhibitors are key therapeutic agents, particularly in oncology, yet their clinical efficacy is often hampered by off-target effects and limited understanding of their cellular target profiles.

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

Irene Khan, expert op het gebied van mensenrechten, werpt een aantal vragen op: Wat kan men verstaan onder een ‘Culture of Justice’? Wie bepaalt wat 'Justice' is? Hoe realistisch is de bevordering van ‘Rule of Law’ en ‘Justice’ in landen waar sprake is van ernstige conflictsituaties en armoede?

Dit boek presenteert een nieuw kader voor de regulering van robots die zijn ontworpen voor emotionele en seksuele interactie, vaak aangedreven door AI.

Op 11 november 2021 verdedigde Evelien Campfens het proefschrift 'Cross-border Claims to Cultural Objects'. Het promotieonderzoek is begeleid door prof.dr. N.J. Schrijver en prof.dr. W.J. Veraart (VU Amsterdam).

The plant hormone auxin regulates plant growth and development through polar cell-to-cell transport-generated maxima and minima. PIN FORMED (PIN) auxin efflux carriers determine the direction of this auxin flow through their asymmetric placement on the plasma membrane (PM).

Dit proefschrift behandelt de vraag of er een level playing field is tussen Europese beleggers die beleggen in EU-beleggingsinstellingen en Europese beleggers die beleggen in Amerikaanse beleggingsinstellingen en, als dit niet het geval is, of de Europese wetgever aanvullende regelgeving zou moeten…

Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

Neurodegenerative diseases pose a large medical and societal challenge. The etiology of these diseases is still poorly understood, which makes drug discovery for these diseases difficult.

Promotor: J. A. Bouwstra

Promotor: Prof.dr. J.W.M. Frenken

This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.

Promotor: S.M. Verduyn Lunel, Co-Promotor: O.W. van Gaans

The thesis explores how interstellar chemistry evolves as a function of time and changing physical architectures during the formation of stars.

By growing in a soil plants change the biotic and abiotic properties of the soil in which they grow.

The aim of this thesis was to study phage infection in Streptomyces, focused on cell wall-deficient cells. Bacteriophages (or phages in short) attach to the cell wall of bacteria after which they replicate and lyse the host cell.

The origin and evolution of galaxies are closely linked to many different physical phenomena.

In this course, you will explore the organs involved in our food digestion and discover the common causes of abdominal and pelvic pain. The latest graphics and animations will give you new insights and understandings of this part of the body.

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.

The global agri-food system plays a critical role in food security and environmental issues.

Cynthia van Vonno, politicoloog aan de Universiteit Leiden, verklaart in haar proefschrift waarom individuele parlementariers meestemmen met hun fractie.

Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.

This course explains the functions of each international court and tribunal in The Hague. On the basis of cases and interviews with judges and lawyers, this course explores the role of these courts and tribunals and their potential to contribute to global justice.

Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…

In deze bundel wordt de regulering behandeld van politieke partijen in de post-communistische EU-landen, met name Bulgarije, Croatië, Tsjechië, Estland, Hongarije, Letland, Litouwen, Polen, Slowakije, Slovenië en Roemenië.

Op 10 oktober 2019 verdedigde Laure d'Hondt haar proefschrift 'Addressing Industrial Pollution in Indonesia. The Nexus between Regulation and Redress seeking'. Het promotieonderzoek is begeleid door promotor prof.dr. A.W. Bedner.

Matthias Haentjens, Jouke Tegelaar en Dorine Verheij schreven het hoofdstuk Financial Market Regulation and Supervision, dat recentelijk is gepubliceerd in het belangwekkende handboek The Law of the European Union (voorheen Kapteyn & VerLoren van Themaat).

The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…

Promotor: J.M. Memelink

Participants in this course will learn to support student teachers and new colleagues in their professional development as teachers, with particular emphasis on the context of bilingual or international education, as in the ICLON World Teachers Programme (WTP).

uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.