Verken ons wonderbaarlijke universum vanuit de plaatselijke kroeg!

Schuurman onderzoekt hoe Rusland zijn geheime operaties tegen Europese landen laat escaleren.

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

With an emphasis on developing novel miktoarm star polymers termed PeptoMiktoStars, this thesis leverages asymmetric polymeric polypept(o)ide frameworks to advance their effectiveness in delivering hydrophobic drugs and nucleic acids.

Promovenda Luisa Prochazkova deed samen met haar collega's van cognitieve psychologie onderzoek naar de effecten van microdoseringen psychedelische drugs op creativiteit. Hun eerste voorzichtige conclusie: je wordt inderdaad creatiever van een klein beetje LSD.

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

Promotor: S.M. Verduyn Lunel, Co-promotor: S.C. Hille

This dissertation consists of two parts, with the common theme

This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…

The main research question of this thesis was: Can nitrogen cycling on dairy farms on peat soil in the Dutch Green Heart area be improved by adapting management to the nitrogen supply from soil and by using other grassland species and crops without affecting milk production?

Promotor: C. W. J. Beenakker, Co-promotor: J. K. Asboth

Het Leiden Advocacy Project on Plastic (LAPP) is een pro bono initiatief aangaande juridische vraagstukken omtrent plastic. LAPP is opgericht om het toenemende probleem van plasticvervuiling aan te pakken en onderzoek te doen naar juridische kwesties gerelateerd hieraan. Studenten werken hierbij als…

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

Promotores: J. Jonkers, K.E. de Visser

The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.

DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.

Like a mixture of oil and water, lipid membranes separate into two liquid phases.

The research presented in this thesis makes use of small molecules (as H2 , D2 and O2 ) on well-defined single crystal surfaces (flat Pt(111), flat Cu(211) and curved Pt(111)) to elucidate the role of surface structure and degrees of freedom in the reactant in specific surface reactions.

This thesis describes how complex and real-world relevant analytical solutions can be found starting from a simple Nagumo problem posed on one or two-dimensional lattices.

Dissociative chemisorption is an important reaction step in many catalytic reactions.

Promotor: G. J. Kroes

Promotor: M. Danhof, Co-promotor: E.C.M. de Lange

In this thesis we study bistable reaction-diffusion equations on lattice domains.

Congres/symposium

This thesis investigates opinion dynamics on random graphs through the lens of the voter model, a classical interacting particle system used to describe how consensus emerges in networks.

Understanding interactions in quantum many-body systems remains one of the most profound and difficult challenges in condensed matter physics.

The dissertation describes TEM experiments on heterogeneous catalysts.

The main topic of this PhD thesis is the Arakelov ray class group of a number field, an algebraic object that contains both the ideal class group structure and the unit group structure.

Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

Promotor: M.T.M. Koper, Co-Promotor: L.B.F. Juurlink

Promotores: R. Cramer, A.K. Lenstra, Co-Promotor: B.M.M. de Weger

To answer questions that look beyond individual entities, network science studies the interactions taking place in complex systems. These complex systems can often have temporal information on when an interaction occurs.

Promotor: Prof.dr. P. Stevenhagen, Jan-Hendrik Evertse, Co-promotor: Pascal Autissier

The aim of this thesis was to develop aluminium salt-based nanoparticles that may ultimately be used as adjuvant in human vaccines.

Microscopic insight on lipid-based nanomedicine in vivo remains limited to the perception of the knowledge that could be obtained: if we interpret only what we see, then we only believe to know. Although believing to know encapsulates an undefined amount of uncertainty in the exploration of lipid-based…

The research described in this thesis centered on retaining exo-β-glucosidases implicated in health and disease, in particular the human inherited lysosomal storage disorder, Gaucher disease (GD).

Promotor: A. Achúcarro, Co-Promotor: J.W. van Holten

Waarom zijn niet alle kinderen even gevoelig voor variaties in hun sociale omgeving?

My PhD research is devoted to studies of the conjectural cluster-algebraic symmetry in the theory of topological string, which is the simplest, however already non-trivial sector in the theory of string.

Polycyclic aromatic hydrocarbons (PAHs) are the most abundant class of organic compounds in space. The PAH field evolves from the constant interaction between experimentalists, theorists, modellers and observers. While laboratory research and quantum chemical calculations together set up the molecular…

Promotor: Prof.dr. C.W.J. Beenakker

Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: V. Vitelli

Shape and biological function are tightly connected. Physical descriptions are used to connect the shape of a biological system with its function.

This thesis deals with properties of Jacobians of genus two curves that cover elliptic curves.

This Thesis focuses on the design and synthesis of ADP-ribosylated compounds that can be applied in biological studies.

Promotor: G.R. de Snoo

De masterspecialisatie Philosophical Perspectives on Politics and the Economy van de Universiteit Leiden was voorheen bekend onder de naam Philosophy, Politics and Economics.

Who are open-source intelligence activists and how reliable are their contributions to public understanding of Russia’s war in Ukraine?

Deze week verscheen 'Dutch Post-war Fiction Film through a Lens of Psychoanalysis' van Peter Verstraten bij Amsterdam University Press, het vervolg op Humour and Irony in Dutch Post-war Fiction Film uit 2016. Elk hoofdstuk in zijn 482 pagina's tellende nieuwe studie begint met een titel van Fons Rademakers…