Hoe moet de EU omgaan met Oekraïne, Wit-Rusland en Moldavië? Hoe kunnen we de Europese Unie helpen om, in een uiterst moeilijke en veeleisende geopolitieke context, zijn politiek ten aanzien van deze landen te heroverwegen?

Streptomyces bacteria are a valuable source of natural products, many of which are used in the clinic or in biotechnology.

Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.

Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

Promotie

As a member of the Research School you can take part in join-in courses. Join-in courses are MA-courses in medieval topics given in set MA-programs of the six participant universities of the Research School. These courses allow you to further specialize in certain topics.

Promotores: Prof.dr. G.A. Persoon & Prof. dr. H.H. de Iongh

Op 5 september 2019 verdedigde Jennifer Doekhie haar proefschrift 'Dimensions of desistance: A qualitative longitudinal analysis of different dimensions of the desistance process among long-term prisoners in the Netherlands'. Het promotieonderzoek is begeleid door promotor prof.dr. P. Nieuwbeerta.

In this thesis chemical and physical processes in the ice mantles on interstellar dust grains are studied.

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

Promotor: P.D. Grünwald

Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.

This thesis is concerned with the constitution of chiral responsive matrix assemblies that may undergo light-driven conformational changes and self-select vibrations to develop vibronic states for driving semi-classical coherent transfer with nearly 100% yield in a lossless NCAP process.

On the largest scale, the Universe resembles a cosmic spiderweb. Most galaxies coexist in small groups within the threads of this web. At the nodes of the threads are enormous groups of galaxies forming the largest structures in the universe still held together by gravity: clusters of galaxies.

De letter M is ontstaan uit een tekeningetje van kabbelend water. Dat leert het kinderboek ‘A is van Os’ waaraan de Leidse egyptoloog Ben Haring een belangrijk aandeel had. In juni kwam het uit.

In this thesis we study the landscape of gravitational models which modify GR by introducing an additional scalar degree of freedom (d.o.f.) to source Cosmic Acceleration.

Studievoorlichting

Workshop

Workshop

Workshop

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.

Studievoorlichting

Neurodegenerative diseases pose a large medical and societal challenge. The etiology of these diseases is still poorly understood, which makes drug discovery for these diseases difficult.

Er zijn voor jou, als kandidaat van de selectie, twee routes die je kunt bewandelen. Afhankelijk van de route (A of B) wordt naar een aantal criteria gekeken. Voor route A kandidaten tellen de 5vwo-overgangscijfers mee; voor kandidaten uit route B niet. Welke route je moet volgen en of je een toelatingsverzoek…

Er zijn voor jou, als kandidaat van de selectie, twee routes die je kunt bewandelen. Afhankelijk van de route (A of B) wordt naar een aantal criteria gekeken. Voor route A kandidaten tellen de 5vwo-overgangscijfers mee; voor kandidaten uit route B niet. Welke route je moet volgen en of je een toelatingsverzoek…

In this dissertation, we work towards an experiment in which we aim to bring a micrometer sized magnet at the tip of a soft cantilever into a superposition.

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…

In this thesis we will explore the use of fuzzy systems theory for applications in bioinformatics.

Surface acoustic waves (SAWs) are mechanical waves that travel along the surface of a material and find many applications in modern technologies due to the ease of excitation on piezoelectric substrates via interdigital transducers (IDTs).

In this dissertation, we study partition-based models that can be used both for interpretable predictive modeling and for understanding data via interpretable patterns.

Deze minor biedt een overzicht van het vakgebied Psychologie.

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

This thesis pioneers diatom molecular identification and quantification through genome-scale methods, with four key aims: (i) reviewing DNA/RNA sequencing methods in aquatic biomonitoring to highlight their strengths and limitations;

Dit boek neemt je stapsgewijs mee in het schrijven van een scriptie, met (voornamelijk) een focus op experimenteel onderzoek, dat het meest veel voorkomt. Door de stappen van experimenteel onderzoek in chronologische volgorde op te splitsen en bij elke stap tips te geven, hopen de auteurs enig houvast…

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: R.G. Boot

We explored the Universe using weak gravitational lensing, a phenomenon that occurs when light from distant galaxies is bent by the gravitational fields of closer cosmic objects, much like how a lens distorts light.

Bij Studeren à la carte of toehoorderschap is er sprake van aanschuifonderwijs: u schuift aan bij een reguliere collegereeks, zonder dat u tentamen aflegt. Na afloop ontvangt u een certificaat van deelname. Hierop staan geen studieresultaten (er is immers geen tentamen afgelegd).

Understanding interactions in quantum many-body systems remains one of the most profound and difficult challenges in condensed matter physics.

Big Science, commonly defined as conventional science made big in three dimensions, namely organizations, machines, and politics, brings a plethora of different stakeholders together, often for a long period of time. This includes policymakers, scientists, (scientific) managers as well as local “host”…

In dit artikel bestuderen de auteurs hoe individuele variabelen en variabelen op landelijk niveau op elkaar inwerken bij het beïnvloeden van politieke genderattitudes in Europa.

Promotie

BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.

Promotor: H.J.M. de Groot

Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.

Promotie

Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.