In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.

One of the major limitations in culturing complex tissues or organs is the lack of vascularization in the cultured tissue. Development of a functional capillary bed could overcome this problem.

This thesis advance our understanding and the application of molecular catalysts relevant to the reduction of oxygen as well as reduction of nitrite.

Binnen FSW is er een kernteam gevormd met contactpersonen binnen de instituten en op faculteitsniveau.

Promotor: Prof.dr. H.V.J. Linnartz

Promotor: Prof.dr. J.N. Kok

Gedurende de coronapandemie veranderde de digitale communicatie van de Chinese overheid met haar burgers. Steeds vaker werd harde propaganda vervangen door ‘soft nieuws’. Promovendus Dechun Zhang bracht de ontwikkelingen in de digitale maatschappij in kaart.

De onderzoeksgroep Organizational & Entrepreneurial Behavior onderzoekt het gedrag van individuen en groepen die in organisaties werken, organisaties starten, of organisaties leiden, met als doel om organisatorische praktijken te informeren. Door zich te concentreren op het gedrag van (groepen) werknemers,…

Kunstmatige fotosynthese heeft als doel om via chemische processen zonne-energie om te zettn in brandstof. Semi-kunstmatige fotosynthese is een hybride aanpak waarbij chemische maar ook biotechnologische processen worden gebruikt. Wij hebben als doel om een hybride systeem te ontwikkelen met behulp…

How and to what extent the historic house (re-)constructs identity through image-making in China.

Xin Zhang, promovendus bij het ICLON, deed onderzoek naar de relatie tussen leermotivatie van docenten en de kwaliteit van hun onderwijs. Promotie op 6 juli.

In this dissertation (titled: Exploring the Synergies between Transfer in Reinforcement Learning and Procedural Content Generation) we explore how the two research fields named in the title, namely Transfer in Reinforcement Learning (TRL) and Procedural Content Generation (PCG) can synergize togethe…

What holds people together and what makes them willing to fit within larger political structures? Our project examines this question in the practices of dynastic rulership in Eurasia ca. 1300-1800.

Goed werkgeverschap is net als goed werknemerschap een open norm. Daarmee is het onduidelijk en onzeker waar werkgevers zich op dienen te richten en welke rechten (en plichten) werknemers hebben in dat verband. De doelstelling van dit onderzoek is om invulling te geven aan de norm goed werkgeverschap…

Optimally solving real-world expensive Black-Box Optimization (BBO) problems w.r.t. real-world constraints, such as wall-clock time and computational costs, is extremely difficult and tedious.

Na het ontvangen van je diploma van LUC, kun je als alumni overal ter wereld heen. Velen die je voor zijn gegaan hebben ervoor gekozen om een master als vervolgopleiding te doen. Sommigen beginnen meteen aan hun professionele carrière of volgen een PhD. Door de vele academische vakgebieden die op LUC…

Promotor: Prof.dr. L.J. Slikkerveer

Op 16 december 2021 verdedigde Lisanne van Houten het proefschrift 'Flexing the Slot Regime'. Het promotieonderzoek is begeleid door prof.dr. P. Mendes de Leon en prof. L. Pierallini (Luiss University Of Rome).

In this thesis,

Promotor: Prof.dr. S. Haring

This dissertation is an experimental study of laser-generated, atmospheric pressure, transient toroidal helium plasmas.

The book ‘Bestrijdingsmiddelen en Milieu' gives a transparent overview of facts and figures concerning pesticide use in the Netherlands and the impact of pesticides on the environment.

Promotor: P.D. Grünwald

Promotor: Prof.dr. G.P. van Wezel

Fungal infections pose a significant threat to individuals with compromised immune systems and despite advancements in diagnosis and treatment, they continue to jeopardize patient’s health.

Patterned detectors are an existing technology that can be found in almost all color cameras.

Lipid formulations have demonstrated strong potential for nucleic acid delivery,particularly with the success of COVID-19 vaccines. Despite these advances, manyaspects of lipid formulations remain unclear.

Freshwater and brackish water ecosystems are arguably the most vulnerable ecosystems on earth, due to concentrated human developments in and around them. The Pontocaspian (PC) region located at the border of Europe and Asia contains a variety of brackish water ecosystems and unique inhabitants, known…

DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.

Curved single crystals provide variable, but well-defined surface structures.

Many galaxy clusters exhibit bright diffuse radio emission that traces the underlying structure of the intracluster medium (ICM).

This work is dedicated to interpreting in cohomological terms the special values of zeta functions of arithmetic schemes.

Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn

An Active Galactic Nucleus (AGN) is a highly luminous region at the center of a galaxy, powered by the accretion into a supermassive black hole and emitting energy from radio waves to gamma rays, often outshining the host galaxy.

Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.

This study attempts to understand how indigenous community institutions pose an important role in sustainable community-based development, including the integration between local culture and development.

Image segmentation is a fundamental task in computer vision, with applications ranging from medical diagnostics to archaeological research.

We developed the bitterling as a unique, well-studied model organism in the area of the evolutionary ecology of brood parasitism. The bitterling-mussel relationship, interspecific mussel host preference, and mussel gill structure are studied in detail, to help understand the developmental adaptation…

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri

In the last decade, the redox interconversion between metal thiolate and disulfide compounds has been extensively investigated for copper, but not for other transition metal ions.

The focus of the dissertation

Natural history collections provide invaluable sources for researchers with different disciplinary backgrounds, aspiring to study the geographical distribution of flora and fauna across the globe as well as other evolutionary processes.

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

The explosive radiation and diversification of the advanced snakes (superfamily Colubroidea) was associated with changes in all aspects of the shared venom system. Morphological changes included the partitioning of the mixed ancestral glands into two discrete glands devoted for production of venom ormucous…

Promotores: Wim Jiskoot; Ferry Ossendorp

The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

Planets are formed in disks of gas and dust around young stars.

This thesis explores the theoretical and observational properties of distant massive galaxies that harbour active black holes in their centres and shine brightly at radio wavelengths.

This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.

This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.