In this thesis, single-cell approaches were applied to characterize the impact of aging on the immunological B cell landscape in different models of atherosclerotic cardiovascular disease, with the goal to identify and study new B cell-associated biomarkers and therapeutic targets to halt atherosclerosis…

Het vertrekpunt van dit onderzoek is de bevinding dat het menselijk brein vatbaar is voor allerlei denkfouten en vooringenomenheden (biases), die onze percepties kleuren en onze redenaties beïnvloeden, zonder dat we dit bewust doorhebben. Integendeel, mensen hebben veelal het gevoel dat zij slechts…

Op 18 april verdedigde Alexandre Tavadian het proefschrift 'De Internationale Publieke Sector: Herdefiniëring van Onafhankelijkheid?'. Het promotieonderzoek is begeleid door Niels Blokker en Brian McGarry.

Op 9 november verdedigde Jonathan Hak het proefschrift 'Niet-tekstueel bewijsmateriaal in internationaal strafrechtelijke vervolgingen: de beste praktijken achterhalen voor het gebruik van audiovisueel materiaal in een digitaal tijdperk. Het promotieonderzoek is begeleid door Carsten Stahn en Jens I…

In this thesis we study the moduli space of genus g curves, and the differential forms that occur naturally on this moduli space.

This thesis is is made of three parts. The first part describes a generalization of the Chabauty's method, that can be used to determine the rational points of a curve such that s+g>r+1, where g is the genusof the curve, r is the rank of the Mordell-Weil group of the jacobian of the curve and s is…

This thesis describes how different colours of light affect various aspects of the growth and development of Arabidopsis and tomato plants⁠.

Promotor: A. Doelman, Co-promotores: P.J.A. van Heijster; A. Zagaris

In this thesis, we have used numerical approaches to study the effects of translational symmetry breaking on strange metallic systems as realised by the holographic duality⁠.

Prof.dr. P. Stevenhagen, Prof.dr. K. Belabas (Universite Bordeaux I)

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.

Promotores: H.W. Lenstra, A. Lucchini

Although plant domestication has significantly altered crop genetics and phenotypes, its effects on the taxonomic and functional diversity of plant-associated microbiomes are not well understood.

This thesis is dedicated to the exploration of the primordial dark ages: unknown physics during the earliest stages of the Universe’s expansion that have not yet been directly probed by observations. Cosmic inflation is a burst of exponential expansion of space after the “Big Bang”.

To contribute to the body of knowledge aiming at a better coverage of ecosystem service assessment in LCA studies, this thesis dives into the challenges of incorporating existing ecosystem service methods within the impact assessment phase of the conventional LCA framework.

When a star gets too close to a supermassive black hole, it is torn apart by strong tidal forces in a tidal disruption event (TDE).

Promotor: J. N. Kok, Co-promotor: A. J. Knobbe

In astronomy, the interpration of observations and measurements plays a crucial role: we rely purely and fundamentally on the information that reaches us as observers. And 80% of all matter in the universe is undetectable directly.

This dissertation presents the synthesis and evaluation of antibody recognition for various capsular polysaccharide (CP) fragments of Staphylococcus aureus (S. aureus).

Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.

Solar energy is used by photosynthetic organisms to drive energy required cellular processes. Is absorbed by two groups of pigments, located in the LHCs.

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

The physical origin of the dozens of stellar-mass binaries, the mergers of which have been detected by the LIGO-Virgo-KAGRA collaboration via gravitational waves, is still unknown.

This dissertation presents new cryptographic protocols, which can be divided into two families.

Promotor: J.W.M. Frenken

Plants, are sessile organisms, have developed strategies to adapt to changes in their environment, in part by altering their growth and development.

If X is a locally compact Hausdorff space, then a representation of the complex C* algebra C_0(X) on a Hilbert space $H$ is given by a spectral measure that takes its values in the orthogonal projections on $H$.

Humans can see the world through the eyes of other humans and imagine what they know, want, and intend. This competence is known as Theory of Mind.

Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.

The increasing resistance of pathogenic bacteria to antibiotics necessitates the discovery of new medicines.

Promotores: E. van Dijk, G.R. de Snoo. Co-promotor: H. Staats

Galaxies are environments where gas coalesces, cools, and is converted into stars. However, it remains unclear the exact mechanisms through which galaxies acquire, redistribute and lose their gas.

The ability to count is a property not often attributed to materials, despite the abundance of memory in materials. Regardless of how a material stores information, it is often difficult to retrieve exactly ‘what’ a material remembers.

All crested and marbled newts (the genus Triturus) suffer from an unusual genetic abnormality, called a balanced lethal system, that kills exactly half of their offspring. How can a trait so disadvantageous have survived millions of years of natural selection?

Multiple stars, that is two or more stars composing a gravitationally bound system, are common in the universe.

This thesis deals with properties of Jacobians of genus two curves that cover elliptic curves.

This thesis discusses the physical and chemical processes than influence the composition of forming planets.

Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis

Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.

Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…

De LL.M. (specialisatie Governance of Migration and Diversity) biedt diepgaande expertise op het gebied van migratie-, asiel-, diversiteits- en non-discriminatierecht met een internationale en Europese focus. De vakken omvatten meerdere academische disciplines, zoals recht, geschiedenis, sociologie,…

Research

eLaw onderzoekt de rol van het recht in de informatiemaatschappij: hoe kan het recht bijdragen aan een goede werking van informatie- en communicatietechnologie, en het gebruik ervan door burgers, bedrijven en overheden?

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Het onderzoek van de afdeling Economie is ondergebracht bij meerdere facultaire programma's. Het onderzoek van de afdeling richt zich thans met name op sociaal-economische vraagstukken, rechtseconomie en fiscale economie.

Het eerste artikel heeft zij samen met Remus Ilies, Klodiana Lanaj en Zen Goh gepubliceerd in het tijdschrift Journal of Vocational Behavior en gaat over de manieren waarop organisaties kunnen voldoen aan de sociale behoeften van hun werknemers.