This thesis investigates how galaxies form and what diversifies the evolutionary histories of galaxies.

Promotor: Prof.dr. D. Bouwmeester, Co-Promotor: M.J.A. de Dood

To this day, all cyclophellitol-based inhibitors and ABPs have been close analogues of their natural substrate counterparts. As a result, these probes showed high selectivity towards their target glycosidases.

Promotores: A.P. IJzerman, H.W.T. van Vlijmen

Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman

All the data stored and processed by our computers is encoded as sequences of zeros and ones, called bits. Quantum computers offer an alternative to this traditional way of encoding and manipulating information.

Promotor: Prof.dr. E.F. van Dishoeck, Prof.dr. F.F.S. van der Tak (RUG)

De genomineerden voor de Prof. Dr. J.Th.J. van den Berg-prijs 2024 en de IRO Thesis Prize 2024. Wie schreven de beste politicologische bachelorscripties?

De genomineerden voor de Prof. Dr. J.Th.J. van den Berg-prijs 2025 en de IRO Thesis Prize 2025. Wie schreven de beste politicologische bachelorscripties?

This dissertation presents a new perspective on the life, work and character of the Dutch physical chemist Jacobus Henricus van ’t Hoff, first recipient of the Nobel Prize in Chemistry, and one of the most important and colourful scientists in Dutch history. The image of Van ’t Hoff that emerges from…

Op 10 november 2021 verdedigde Carmel van Niekerk-Jacobs het proefschrift 'Realising the right to reproduce with assistance in South Africa'. Het promotieonderzoek is begeleid door prof.dr. J.J. Sloth-Nielsen en prof.dr. T. Liefaard.

The thesis is part of a bigger project, the HEPGAME (High Energy Physics Game). The main objective for HEPGAME is the utilization of AI solutions, particularly by using MCTS for simplification of HEP calculations.

The confinement of molecular catalysts in metal-organic frameworks has the potential to lead to significant improvements in selectivity, long term activity and catalyst stability.

Despite their ecological, cultural, and economic importance, lion (Panthera leo) populations in Kenya are declining rapidly due to retaliatory killings following livestock depredation, depletion of wild prey, habitat loss driven by human activities, climate change, and disease.

Cell-based medicinal products (CBMPs), such as CAR T cells, are highly complex biopharmaceutical products offering various treatment options for serious illnesses such as cancer or autoimmune diseases.

Promotor: Prof.dr. M. Danhof

Promotor: Prof.dr. S. Haring

The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…

Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.

What is the current relevance of the ethics of counterterrorism and what is the added value of ethics support within the practice of counterterrorism?

Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.

With the dramatic growth of the image data on the web, there is an increasing demand of the algorithms capable of understanding the visual information automatically.

The work presented in this thesis is based on ALMA surveys of protoplanetary disks in three star-forming regions: Lupus, OMC-2, and NGC 2024.

Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

Promotor: K. Kuijken, Co-Promotor: H. Hoekstra

Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

In this thesis, we study systems of electrons in which strong correlations give rise to emergent exotic physics.

Cathodic corrosion is a relatively unknown phenomenon that can severely etch metallic electrodes at cathodic (negative) potentials.

This work is dedicated to interpreting in cohomological terms the special values of zeta functions of arithmetic schemes.

The research described in this thesis centered on retaining exo-β-glucosidases implicated in health and disease, in particular the human inherited lysosomal storage disorder, Gaucher disease (GD).

Trigonostemon Blume is a plant genus in the family Euphorbiaceae comprising 59 species.

Mycorrhizas are symbiotic associations between soil fungi and most plant species.

The effects of anthropogenic noise on interactions between predators and their prey are still little understood.

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

Organic amendments applied to agricultural fields can partially offset our carbon emissions to the atmosphere and improve the resilience of agriculture to the effects of climate change. Driving these benefits, however, are complex and poorly understood interactions between organic amendment properties,…

The prevalence of obesity (BMI >40 kg/m2) has increased rapidly over the recent years, not only in adults, but also in children and adolescents.

Promotor: Prof.dr. A.W. van der Vaart

Promotor: C.A.J. Knibbe, Co-promotor: J.J. Boelens, R.G.M. Bredius

Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp

The CC chemokine receptor 2 (CCR2), a member of the G protein-coupled receptor (GPCR) superfamily, is widely involved in autoimmune and inflammatory diseases. However, no drugs for this receptor have made it to the pharmaceutical market yet.

Promotor: E. Gittenberger, Co-promotor: B.W. Hoeksema

In this thesis, we use low-frequency and high-frequency radio observations to address the following questions regarding quasars: is the radio loud/quiet quasar dichotomy real?

Tin electrodeposition applications have rapidly evolved in the past 25 years.

This thesis describes the design, characterization and application of dextran based crosslinked network.

Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown

This thesis is a collection of theoretical works aiming at adjusting quantum algorithms to the hardware of quantum computers.

A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

Promotor: W. Jiskoot, Co-promotor: A. Hawe

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

Microscopic insight on lipid-based nanomedicine in vivo remains limited to the perception of the knowledge that could be obtained: if we interpret only what we see, then we only believe to know. Although believing to know encapsulates an undefined amount of uncertainty in the exploration of lipid-based…