In de serie Humans of Humanities, lichten wij iedere twee weken een van onze wetenschappers, medewerkers of studenten uit.

During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.

Wat is 'Interaction between Legal Systems' (ILS) en wat betekent het als profileringsgebied binnen de Faculteit der Rechtsgeleerdheid? Hier meer over op de startbijeenkomst van ILS 2.0 op 26 oktober 15.00 – 17.00 in de Grotiuszaal (A051 KOG). De middag wordt afgesloten met een borrel in de Global Lo…

Promotor: A.P. IJzerman Co-promotor: L.H. Heitman

In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.

Van zelfrijdende auto’s tot innovatieve medicijnontwikkeling, kunstmatige intelligentie (AI) gaat ons leven op uiteenlopende manieren fundamenteel veranderen. Onze computerwetenschappers bestuderen de technologie op een diep en fundamenteel niveau. Maar we zoeken ook naar medische toepassingen en antwoorden…

There is no human society that does not employ a rich and diverse language. This course introduces you to linguistics, featuring interviews with well-known linguists and with speakers of many different languages. Join us to explore the miracles of human language!

The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.

Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri

Het LUMC iPSC Hotel biedt de generatie van research grade humane geïnduceerde pluripotente stamcellen (iPSC's) uit verschillende weefselbronnen met behulp van de modernste herprogrammeringstechnieken.

Melanie Fink, Postdoctoraal Onderzoeker bij het Europa Instituut van de Universiteit Leiden, heeft haar boek Frontex and Human Rights, Responsibility in 'Multi-Actor Situations' under the ECHR and EU Public Liability Law gepubliceerd. Dit boek is gebaseerd op haar proefschrift, dat zij in december 2017…

The endophytic microbiota is a community of various microorganisms that reside in plant tissue. These microbes are known to promote plant health and resilience, and their members do not simply exist side by side.

A management strategy has been developed for field margins to reduce pesticide drift to non-target areas and to promote biodiversity on arable land. To this end, 3 and 6 m wide strips along the edges of winter wheat, sugar beet and potato crops have been left unsprayed with herbicides and insecticides…

This project explores themes at the intersection of maritime history and environmental history by looking at the problems Dutch ships encountered in the different climates of the Atlantic and Indian Ocean worlds, and the solutions they could provide.

Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…

Leiden University’s Master of Law in European and International Human Rights Law (L.L.M.) looks at the various protection mechanisms applied to human rights across different political, social and cultural settings.

This thesis combines field and laboratory studies to address some of the most pressing questions in the field of microplastic research.

Promotor: Prof.dr. M. Ubbink

This thesis focus on the interaction between M dwarf stellar winds and Galactic cosmic rays and the possible effects on the habitability of exoplanets.

Promotor: Prof.dr. M. Ubbink, Co-promotor: G. Siegal

Op 21 februari 2019 verdedigde Ruben Zandvliet zijn proefschrift 'Trade, Investment and Labour: Interactions in International Law'. Het promotieonderzoek is begeleid door promotor prof. dr. N.J. Schrijver.

The primary goal of this research is to deepen our understanding of substrate-enzyme interactions in Glycoside hydrolases. For this purpose, Bacillus circulans xylanase (BcX) has been selected as a well-established model to examine the Michaelis complex and glycosyl-enzyme adduct.

Plants and their pollinators form complex interaction networks. Within these networks, species differ widely in the number of species they interact with.

Woensdag 13 december verdedigde Melanie Fink haar proefschrift ‘Frontex and Human Rights: Responsibility in “Multi-Actor Situations” under the ECHR and EU Public Liability Law’.

Promotor: Prof.dr. M. Danhof

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

The way organisms develop from the initial single-cellular state to a complex final assembly like the human body, and how the final body is maintained throughout life, is one of the greatest mysteries and it’s understanding one of the biggest scientific challenges.

Op 21 januari 2020 verdedigde Patrick van Berlo zijn proefschrift 'Human Rights Elephants in an Era of Globalisation: Commodification, Crimmigration, and Human Rights in Confinement'. Het promotieonderzoek is begeleid door promotoren prof.dr. J.P. van der Leun en prof.mr.dr. M.A.H. van der Woude.

Humans share meaning through language. Over time, repeated interactions have shaped languages into forms that match our cognitive preferences, making them structured, expressive, easy to learn, and ultimately, meaningful.

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

In this thesis, the role of mast cells in atherosclerosis and novel therapeutic strategies to inhibit atherosclerosis progression are discussed. The first part of the thesis specifically focuses on the relation between mast cells and advanced human atherosclerotic plaque characteristics.

Almost three years after receiving her honorary doctorate, Dr Graça Machel returned to Leiden University. Over the course of two days she spoke with students, researchers, and other interested persons, about human rights – particularly those of women and children – in a world in which these are continually…

Bij Cambridge University Press (CUP) verscheen onlangs van Ingrid Leijten het boek Core Socio-Economic Rights and the European Court of Human Rights. Het boek maakt onderdeel uit van de serie Cambridge Studies in European Law and Policy en heeft als onderwerp de bescherming van sociaaleconomische rechten…

The thesis describes the development, synthesis and biological evaluation of several proteasome inhibitor designs. Mainly, this work focusses on designing proteasome inhibitors that selectively inhibit the immunoproteasome, while leaving the constitutive proteasome mostly, if not completely, untouch…

The Encyclopedia of Global Human Migration biedt een complete verkenning van de prominente thema's, gebeurtenissen en theoretische onderbouwingen van de verplaatsingen van menselijke bevolkingsgroepen van de prehistorie tot heden.

Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.

Kom naar onze online en oncampus events om ons beter te leren kennen!

Op vrijdag 24 februari zal Prof. Judith Masson (Bristol University), Hoogleraar Rechtssociologie en Fellow bij the UK Academy of Social Science, een lezing geven binnen de Leiden Socio-Legal Series.

Sinds 1974 wordt Wereldmilieudag elk jaar gevierd op 5 juni, waarbij regeringen, bedrijven en burgers worden betrokken bij een poging dringende milieukwesties aan te pakken.

The European Council and the European Commission have a similar role in agenda setting. Both place issues on the EU agenda. However, these institutions have distinct designs. They have different political attributes (the European Council has considerably more political authority) and information-processing…

The studies described in this thesis deal with glycosidases, in particular alpha-galactosidases.

The findings in this thesis improve the understanding of 1) the relationship between exposure characteristics and toxicity of ENPs, 2) the joint toxic action of ENP mixtures and the comparison to metal salt mixtures, 3) how NOM affects the individual and joint toxicity of ENPs, 4) the extent of trophic…

Promotor: J.S. Kaastra Co-promotor: E. Constantini

The rapidly increasing commercial application of metallic nanoparticles within products will inevitably enhance the amount of NPs being released into soil.

This thesis has shed light on some of the ways in which the local electrolyte composition can differ from the bulk and how these changes in the local reaction environment can determine the activity and/or selectivity of two important electrocatalytic reactions, namely, electrochemical CO2 reduction…

Promotor: M.T.M. Koper, Co-promotors: A.I. Yanson, L.B.F. Juurlink

This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.

Promotores: G.R. de Snoo, B. Sinsin, Co-Promotor: H.H. de Iongh