Evenement

Op vrijdag 17 september vond een symposium plaats ter gelegenheid van het afscheid van Wim Blockmans als hoogleraar Middeleeuwse geschiedenis. Aansluitend hield hij zijn afscheidsrede en presenteerde daarbij zijn nieuwe boek Metropolen aan de Noordzee.

Sinds 1 september is Jaap Ligthart als AIO verbonden aan het instituut voor Geschiedenis. Hij doet onderzoek naar de financiële problematiek van vijftiende-eeuwse vorsten in de Lage Landen.

Boekpresentatie

This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.

De winnaar van de Master scriptieprijs 2014 van het Holland Historisch Tijdschrift is niemand minder dan alumna van de Universiteit Leiden Sanne Wirken, met haar scriptie Jan Kluit en Hendrik Moerings. Media en identiteit in de Republiek, 1747 – 1800.

Op 18 november 2021 verdedigde Anneke Keulemans het proefschrift 'Het Unierechtelijke verdedigingsbeginsel'. Het promotieonderzoek is begeleid door prof.mr.dr. J.P. Boer en prof.dr.mr. A.O. Lubbers.

In this project of the Center for Public Values & Ethics (CPVE) ongoing research is conducted on the history of advice to Dutch central government by so-called State committees from 1814 to 2014. State committees have been installed by Dutch central government since 1814 to provide expert advice, research…

Alumni-activiteit

All crested and marbled newts (the genus Triturus) suffer from an unusual genetic abnormality, called a balanced lethal system, that kills exactly half of their offspring. How can a trait so disadvantageous have survived millions of years of natural selection?

For centuries astronomers studied the Universe by collecting light. Nowadays, we are living in times of great technological advancements, which allow us to explore our Universe in a new way - though gravitational wave radiation.

Promotor: Thomas Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto

This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.

Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn

Promotor: Prof.dr. J.N. Kok, Co-Promotor: W.A. Kosters

Promotor: Prof.dr. G.P. van Wezel

Promotor: P.D. Grünwald

The sequence-dependence of biomolecular interactions involving nucleic acids and proteins is essential for numerous processes inside the cell. Insights into the underlying molecular mechanisms have been obtained using various biochemical and biophysical methods on two different levels — bulk and sin…

Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.

In this work, I explore the creation of new methods that optimize simulations of the gravitational N-body problem. Specifically, I take advantage of the recent popularity of Machine Learning methods to find tools that can suit this problem.

The marine shipping industry is one of the strongest emitters of nitrogen oxides (NOx), a pollutant detrimental to ecology and human health. Over the last 20 years, the pollution produced by power plants, the industry sector, and cars has been decreasing.

Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…

The progressive loss and degeneration of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD). The onset and progression of PD can be triggered by multiple risk factors, for instance, genetic mutation, environmental exposure, and aging.

Big Science, commonly defined as conventional science made big in three dimensions, namely organizations, machines, and politics, brings a plethora of different stakeholders together, often for a long period of time. This includes policymakers, scientists, (scientific) managers as well as local “host”…

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

Whilst government’s ability to design ‘context-specific’ regional innovation policy is generally assumed to depend on the region’s decision-making power, the aim of this study is to investigate how regional government matters. In order to open up the black box of policy design, the study develops a…

Promotor: S.M. Verduyn Lunel, Co-Promotor: O.W. van Gaans

In light of climate change, it is crucial to determine whether plant species can adapt to future climates to avoid extinction. Plants adapt to various conditions by altering their functional traits, such as leaf size or photosynthetic rate. Some traits appear linked and vary together between species,…

Promotor: J. N. Kok, Co-promotor: A. J. Knobbe

There is an urgent need for more physiologically relevant cell culture methods to guide compound selection in pre-clinical stages of the drug development pipeline.

Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma

Promotor: S.M. Verduyn Lunel

Industrial manufacturing processes, such as the production of steel or the stamping of car body parts, are complex semi-batch processes with many process steps, machine parameters and quality indicators.

This PhD thesis concerns the topic of arithmetic geometry. We address three different questions and each of the questions in some way is about counting how big some set is or can be.

This thesis introduces a relational interaction model and a practical tool for describing, visualising and generating interactive dialogues.

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.

This research delves into the unique cultural approach of the Tenggerese people, an Indigenous community in East Java, Indonesia, regarding elderly care. It focuses on their traditional practices of bakti (‘filial piety’) and sayan (‘mutual aid’), deeply ingrained in the community's lifestyle and va…

Promotor: Prof.dr.ir. E. Deprettere

In condensed matter systems electron-electron interactions, negligible in everyday metals, can dramatically alter the electronic behavior of the system. Examples of such altered behavior include high-temperature superconductivity and modulation of the electron density.

Interactive exploration of large volumes of data is increasingly common, as data scientists attempt to extract interesting information from large opaque data sets. This scenario presents a difficult challenge for traditional database systems, as (1) nothing is known about the query workload in advance,…

Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder

Promotores: J.N. Kok, H.J. Hoogeboom

Promotor: J.A. van Veen, Co-promotor: E.E. Kuramae

This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.

Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen

This thesis studied in depth the energy use and CO2 emissions of the industrial sector in China.