Dr. Helen Pluut heeft een artikel gepubliceerd in het gerenommeerde tijdschrift Organizational Behavior and Human Decision Processes (OBHDP) in samenwerking met Remus Ilies (National University of Singapore), Petru Curşeu (Open Universiteit en Babeş-Bolyai University) en Yukun Liu (University of Western…

Why do sexual violence policies still fail to systematically address men and masculinities, when the need for cultural change among men has been central in public debates since #MeToo?

This thesis is devoted to an in-depth examination of the various effects of disorder in the cuprate high-temperature superconductors.

Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…

Promotor: Prof.dr. H.J.A. Rottgering

Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…

The aim of this thesis was to develop novel treatment strategies for different types of eye melanoma utilizing zebrafish models. We first establish orthotopic and ectopic xenograft models for uveal and conjunctival melanoma by engraftment of the immortalized cells derived from these tumors into zebrafish…

The main aim of my Ph.D. thesis is to further explore the value of using early developing zebrafish larvae (up to 5 dpf) as a model to study anxiety-like behaviour and their pharmacological modulation with drugs.

The use of N fertilizers has increased worldwide in the past century. While this increased input of N has increased food productivity, it has also contributed to decreases in biodiversity, soil quality and environmental health, including increases in greenhouse gas emissions.

This thesis develops a method for direction dependent calibration of the ionosphere in radio interferometric data.

The aim of this thesis was to study phage infection in Streptomyces, focused on cell wall-deficient cells. Bacteriophages (or phages in short) attach to the cell wall of bacteria after which they replicate and lyse the host cell.

Promotor: G.R. de Snoo, Co-promotores: M.G. Vijver, J.P.M. Vink

The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.

Op 22 januari jl. verscheen het artikel: 'Drie valkuilen en denkfouten in de drang naar een kleinere overheid' van prof. dr. Frits M. van der Meer & Mr. dr. G.S.A. Dijkstra op de site van Mejudice:

Onderwijs- en Onderzoeksmedewerker Ola Al Khatib (afdeling Staats- en bestuursrecht) schrijft over ad hoc biases door 'supervised machine learning' algoritmes in de publieke sector en betoogt dat dit fenomeen aanleiding geeft om het debat over onze huidige opvatting over discriminatie intensiever te…

Deze minor is bedoeld voor studenten met een brede interesse in het functioneren van de publieke sector in al haar verscheidenheid die, bovendien, een bijdrage willen leveren aan het verbeteren van publieke dienstverlening.

This article examines the consequences of stereotypical beliefs regarding gender, traits, and leadership styles for manager preferences.

Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman

Welke rol spelen stress en angst bij de vorming van nocebo hyperalgesie?

Vrijdag 6 november heeft een symposium plaatsgevonden naar aanleiding van de publicatie van het Research Handbook on Crisis Management in the Banking Sector, geredigeerd door professor Haentjens en professor Wessels.

De masteropleiding Law and Society, aangeboden door het Van Vollenhoven Instituut voor Recht, Bestuur en Samenleving aan de Universiteit Leiden, biedt je de vaardigheden en kennis die nodig zijn voor een succesvolle carrière in zowel de private als de publieke sector.

Het Leiden Institute of Advanced Computer Science (LIACS) verzorgt het bachelor- en masteronderwijs voor informatica aan de Universiteit Leiden.

Lipid formulations have demonstrated strong potential for nucleic acid delivery,particularly with the success of COVID-19 vaccines. Despite these advances, manyaspects of lipid formulations remain unclear.

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

Promotor: K. Kuijken, Co-Promotor: H. Hoekstra

Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn

Promotor: A. Achúcarro Co-promotor: A. Boyarsky

This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

Promotor: V. Vitelli, Co-promotor: J. Paulose

De afdeling Environmental Biology (CML-EB) houdt zich bezig met vraagstukken rondom biodiversiteit en natuurlijke hulpbronnen op het platteland in westerse en niet-westerse gebieden.

The main goal of the research described in this thesis was the development of new photoactivated chemotherapy (PACT) ruthenium(II) complexes bearing a non-toxic photolabile ligand.

Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang

Advanced UHF MRI techniques provide powerful tools for studying the zebrafish brain, an emerging model in neurological research. In this work, various MRI and localized MRS methods are optimized and employed for UHF strength for studying the zebrafish brain.

This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn

The main research question of this thesis was: Can nitrogen cycling on dairy farms on peat soil in the Dutch Green Heart area be improved by adapting management to the nitrogen supply from soil and by using other grassland species and crops without affecting milk production?

One of the effects of climate change is the phenomenon of desertification, a process that occurs in semi-arid and arid areas and causes land degradation as well as vegetation loss. Due to the lack of resources, vegetation self-organizes to sustain itself by forming large-scale spatial patterns.

The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.

Atherosclerosis is the most prominent underlying pathology of cardiovascular disease and an important cause of major adverse cardiovascular events.

Pseudomonas Aeruginosa is a Gram-negative bacterium which can form biofilms, increasing its resistance against antibiotics and the host immune system. Polysaccharides are an integral part of this biofilm, one of these polysaccharides is called Psl. PslG is a glycosidase, able to cleave this polysaccharide,…

Consequences for sediment stability and seston trapping

Endothelial dysfunction and microvascular diseases are key drivers of cardiovascular disease, the world's leading cause of death.