In the past decade many population studies have been performed with the Atacama Large Millimeter/submillimeter Array (ALMA) to understand the bulk properties of protoplanetary disks around young stars. These population studies mostly consisted of low mass stars, with relatively few of the disks around…

Promotor: Prof.dr. E.F. van Dishoeck, Co-Promotor: G.J. Herczeg

What is the effect of light at night on plant phenology and physiology, and how does this affect plant interactions with other species?

De Verenigde Naties hebben 11 februari uitgeroepen tot International Day of Women & Girls in Science. De Universiteit Leiden viert deze dag met een open publieksevenement met vrouwelijke topwetenschappers van haar bètafaculteit. Iedereen is welkom vanaf 13:30 uur in het Kamerlingh Onnesgebouw in Lei…

This dissertation revolves around the design and implementation of novel instrumentation and related measurement techniques, at the single molecule level, for use in biophysical research. Chapter 1 presents an introduction to the field of fluorescence-based single molecule measurements. In particular,…

Promotor: Prof.dr. M. Danhof

This thesis is a collection of experimental attempts to enhance photoluminescence of fluorescent molecules and quantum dots with single gold nanorods (GNRs) and relevant applications.

Promotor: Prof.dr. S. Haring

In human cells, a meter-long DNA is condensed inside a micrometer-sized cell nucleus. Simultaneously, the genetic code must remain accessible for its replication and transcription to functional proteins.

This dissertation is an experimental study of laser-generated, atmospheric pressure, transient toroidal helium plasmas.

The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.

The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…

Promotor: K.E. Schalm, Co-promotor: S.S. Lee

In this thesis, we study systems of electrons in which strong correlations give rise to emergent exotic physics.

Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn

Promotor: Prof.dr. E. Eliel, Co-Promotor: M.J.A. de Dood

Organic amendments applied to agricultural fields can partially offset our carbon emissions to the atmosphere and improve the resilience of agriculture to the effects of climate change. Driving these benefits, however, are complex and poorly understood interactions between organic amendment properties,…

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

Tin electrodeposition applications have rapidly evolved in the past 25 years.

This thesis describes the role of pollution, specifically neonicotinoid insecticides, as an actor of the ongoing biodiversity decline.

Promotor: M.T.M. Koper, Co-promotors: A.I. Yanson, L.B.F. Juurlink

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

Green hydrogen is produced via a process called water electrolysis. During electrolysis water is split into oxygen and hydrogen.

Promotor: Roeland M.H. Merks

There are many interpretations of quantum mechanics, and ultimately experiments are needed to verify or falsify these interpretations.

Promotor: Prof.dr. M.L. van Hecke

In most applications, electrocatalysts exhibit a large surface area to volume ratio, for example using nanoparticles.

Promotor: Prof.dr. P.G.L. Klinkhamer, Co-Promotor: T.J. de Jong

The research in this thesis is focused on tomographic reconstruction based on two imaging modalities in electron microscopy.

Promotor: J.W.M. Frenken

Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.

In this thesis, we describe the latest advances in SQUID-detected Magnetic Resonance Force Microscopy (MRFM).

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

Despite the history of studies on methanol formation from CO2, the dominant elementary reaction steps that constitute the chemical mechanism for this catalyzed process are not determined.

The focus throughout this thesis will be on gathering fundamental studies of the detailed structure and composition of the electrode/electrolyte interface effect on the rate and mechanism of key electrocatalytic reactions.

Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…

Humans can see the world through the eyes of other humans and imagine what they know, want, and intend. This competence is known as Theory of Mind.

This PhD thesis concerns the topic of arithmetic geometry. We address three different questions and each of the questions in some way is about counting how big some set is or can be.

Promotores: E. van Dijk, G.R. de Snoo. Co-promotor: H. Staats

Promotores: J. Jonkers, K.E. de Visser