604 zoekresultaten voor “cognitive formation” in de Publieke website
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The interplay between stars, gas and dust in faint star-forming galaxies
When observing star-forming galaxies, we are not only seeing stellar light, but we also see how this interacts with galactic gas and dust. This thesis contains studies of the stellar, nebular and dust properties of low mass star-forming galaxies.
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Functional analysis of agrobacterium tumefaciens virulence protein VirD5
Supervisor: P.J.J. Hooykaas
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When galaxy clusters collide: the impact of merger shocks on cluster gas and galaxy evolution
Promotor: Prof.dr. H.J.A. Rottgering
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Inextricable ties between chemical complexity and dynamics of embedded protostellar regions
Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh
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Molecular characterization of copper-dependent enzymes involved in Streptomyces morphology
Promotor: G.P. van Wezel, Co-promotor: D. Claessen
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Selectivity and competition between the anodic evolution of oxygen and chlorine
Sustainable energy from wind and solar is most readily available near the sea.
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Shining Light on PAHs in Space
Polycyclic aromatic hydrocarbons (PAHs) are the most abundant class of organic compounds in space. The PAH field evolves from the constant interaction between experimentalists, theorists, modellers and observers. While laboratory research and quantum chemical calculations together set up the molecular…
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High-contrast imaging polarimetry of exoplanets and circumstellar disks
Understanding the formation and evolution of planetary systems is one of the most fundamental challenges in astronomy. To directly image and study young exoplanets and the circumstellar disks they form from, dedicated high-contrast imaging instruments are built.
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Innovation and stasis
The name ‘Jambi flora’ refers to fossil plants found as part of a rock formation from the Early Permian (296 million years old), located in the Jambi Province of Sumatra, Indonesia.
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Big simulations for big problems
In this thesis we investigate cosmology and the large scale structure of the Universe using cosmological simulations.
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Tales of Orion: the interplay of gas, dust, and stars in the interstellar medium
Promotores: Prof.dr. A.G.G.M. Tielens, Prof.dr. L. Kaper (UvA)
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The connection between mass and light in galaxy clusters
Promotor: Koen Kuijken Co-promotor: Henk Hoekstra
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Multiscale mathematical biology of cell-extracellular matrix interactions during morphogenesis
During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.
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Resolving gas-phase metallicity in galaxies
Galaxies are environments where gas coalesces, cools, and is converted into stars. However, it remains unclear the exact mechanisms through which galaxies acquire, redistribute and lose their gas.
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Gold nanoparticle-peptide conjugates for biomedical applications
Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.
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The environmentally-regulated interplay between local three- dimensional chromatin architecture and gene expression
Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.
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Involvement of host and bacterial factors in Agrobacterium-mediated transformation
Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.
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Visualizing strongly-correlated electrons with a novel scanning tunneling microscope
Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.
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Forever Young: How AHL15 delays developmental phase transitions to prevent ageing in plants
The AT-Hook Nuclear Localized 15 (AHL15) gene belongs to a plant-specific gene family of DNA-binding proteins. Overexpression of AHL15 in Arabidopsis thaliana delays developmental phase transitions whereas its loss of function causes a slight acceleration.
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Arabidopsis AGC3 kinases and PIN plasma membrane abundance
The plant hormone auxin plays a central role in the growth and development of plants. Auxin acts in a concentration dependent manner and polar cell-to-cell transport of this hormone determines its distribution in the tissues of plants. This polar auxin transport is mediated by several families of auxin…
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Systems pharmacology of the amyloid cascade
According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).
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Insights into the mechanism of electrocatalytic CO2 reduction and concomitant catalyst degradation pathways
This work describes several studies into the electroreduction of carbon dioxide (CO2RR), both regarding mechanistical aspects and catalyst stability considerations. Mechanistic insights into carbon-carbon bond formation on a silver catalyst are described in Ch 2, were we find an acetaldehyde-like surface…
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The Role of Linker DNA in Chromatin Fibers
The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.
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Novel analytical approaches to characterize particles in biopharmaceuticals
Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).
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A time-space translation mechanism for patterning the vertebrate anteroposterior axis
My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.
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Exploring Reactive Interfaces: Nanoplastics, Catalysts, and 2D Materials
This thesis investigates reactive interfaces in surface science across three domains: heterogeneous catalysis, environmental nanoplastics, and two-dimensional materials.
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Innovative diagnostics and treatments
Hoe meer we leren over een (neuro-)psychologische of lichamelijke aandoening en de hieraan gerelateerde gedragsfactoren, hoe beter we deze niet alleen kunnen signaleren, maar ook behandelen. Het is dus belangrijk dat recente inzichten over (neuro-)psychologische problemen en daaraan gerelateerde gedragsfactoren…
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Onderzoek
In de Faculteit der Sociale Wetenschappen is de verwevenheid van onderzoek, onderwijs en impact vanzelfsprekend.
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A radio view of dust-obscured star formation
Promotie
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Microscopy and Spectroscopy on Model Catalysts in Gas Environments
In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska
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Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
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Heterogenized molecular (pre)catalysts for water oxidation and oxygen reduction
Before the large scale use of renewable energy sources can be implemented in our society, the storage of electrical energy needs to be tackled. Storage the energy as hydrogen via the reduction of protons is a good option.
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Van woord tot akkoord. Een analyse van de partijkeuzes in CPB-doorrekeningen van verkiezingsprogramma's en regeerakkoorden, 1986-2017
This PhD-thesis analyses the relationship between the parties’ choices in the CPB Netherlands Bureau for Economic Policy Analysis’ assessments of the election manifestos and coalition agreements over the period 1986-2017, and tries to explain this relationship.
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The holographic glass bead game: from superconductivity to time machines
Promotores: Prof.dr. J. Zaanen, Prof.dr. K.E. Schalm
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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The assembly history of the milky way nuclear star cluster
Promotor: P. T. de Zeeuw, Co-promotor: N. Neumayer; G. van de Ven
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Photo-activation of ruthenium-decorated upconverting nanoparticles
Metal-based prodrugs based on ruthenium(II) polypyridyl complexes have proven to be very suitable for application in both photodynamic therapy (PDT) and photo-activated chemotherapy (PACT).
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Cholesterol metabolism in mouse models of atherosclerosis and adrenal steroidogenesis
Cholesterol influences many pathways, including serving as precursor for adrenal steroidogenesis. Imbalance of cholesterol levels has been implicated in several diseases including cardiovascular diseases and its underlying pathology, atherosclerosis.
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Strategy Dynamics
In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.
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De verzamelwoede van Martinus van Marum (1750-1837) en de ouderdom van de aarde
Promotor: F.J. van Lunteren, E. Jorin
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Massieve sterren als fabriek voor de bouwstenen van het leven
NASA’s telescoop SOFIA geeft een nieuw kijkje in de chemie nabij jonge sterren: de geboorteplaats van nieuwe planeten. De Leidse promovendus Andrew Barr schrijft erover in de Astrophysical Journal. Hij en zijn collega’s vonden enorme hoeveelheden water en organische moleculen in de wervelende, schijfvormige…
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Juridische oordeelsvorming in het aansprakelijkheidsrecht en financieel toezicht
Het vertrekpunt van dit onderzoek is de bevinding dat het menselijk brein vatbaar is voor allerlei denkfouten en vooringenomenheden (biases), die onze percepties kleuren en onze redenaties beïnvloeden, zonder dat we dit bewust doorhebben. Integendeel, mensen hebben veelal het gevoel dat zij slechts…
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op: “The Circle of Life: from the beginning of the universe to the formation of life”
Lezing, Kaiser Lente Lezing
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Premasterprogramma
Maak je plannen voor een masteropleiding Psychologie? Beschik je over een verwante, afgeronde Nederlandse hbo- of wo-bacheloropleiding? Dan kán het eenjarige premasterprogramma Psychologie iets voor jou zijn.
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Wat zit er achter het scherm? Verwachtingen van baby's van 10 maanden over verborgen voorwerpen
Het begrijpen van de wereld om ons heen hangt af van het vermogen om de wereld te ontleden in verschillende objecten en deze in hun geheugen op te slaan. Dit proces wordt gedefinieerd als object individuatie. Onderzoek wijst uit dat dit voor baby’s niet altijd gemakkelijk is.
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Welkom bij de Leidse Faculteit der Sociale Wetenschappen
Actuele vraagstukken uit zowel Nederland als de internationale gemeenschap, zetten we in om de nieuwsgierigheid van studenten en onderzoekers te prikkelen.
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Francien Dechesne benoemd tot bijzonder hoogleraar AI en recht aan Tilburg University
Met ingang van 1 november 2025 is universitair hoofddocent Ethics and Digital Technologies Francien Dechesne benoemd tot bijzonder hoogleraar ‘Data and AI for the Rule of Law’ aan de Tilburg School of Humanities and Digital Sciences van Tilburg University.
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Meertaligheid van Friese kinderen: Evelyn Bosma wint Keetje Hodshonprijs
Postdoc en taalwetenschapper Evelyn Bosma ontvangt voor haar proefschrift de Keetje Hodshonprijs. Voor haar onderzoek over meertaligheid van Friese kinderen won Bosma eerder al de Klokhuis Wetenschapsprijs en de Wetenschapsprijs Campus Fryslân.
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Canonical Cultures network
Religion, Philosophy, and the Pre-modern World