The 2025 Data for Policy conference at Leiden University explored how digital and green transitions can shape a more sustainable and inclusive future.

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

OB associations are loose groups of young, massive stars. They constitute the last stage of the massive starformation process, and the context in which new stars are formed.

n this thesis we study curves. In the first half, we study moduli spaces of curves and Gromov-Witten invariants, certain kinds of curves counts. We employ logarithmic geometry for this.

Denk je aan geesteswetenschappen, denk je misschien niet meteen aan een nieuwe superserver. Toch is die inmiddels net in gebruik genomen. Universitair docent Jelena Prokic van het Centre for Digital Humanities vertelt meer over deze ontwikkeling.

The intradermal administration route is attractive for vaccine delivery, because of the highly populated antigen-presenting cells in the skin. However, the skin’s main physical barrier, the stratum corneum, prevents vaccines from entering the skin.

Cristina Grasseni’s project

Promotors: Prof.dr. T.H.W. Bäck, Prof.dr. B. Sendhoff (Technische Universität Darmstadt)

Promotor: K.J. Batenburg, Co-promotor: A.W. van der Vaart, B. de Smit

Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe

Natural vanilla flavor is one of the most important in the world. However, the cost of this flavor is expensive. Production of this flavor by alternative methods, could reduce the cost.

This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.

This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.

The thesis focuses on synthesis strategies in oligosaccharide campaigns, and the influence of protecting groups.

The idea of citizens and public professionals collaborating to provide public services has widely spread in several countries around the globe. Co-production is often presented as the go-to solution for challenges like a legitimacy crisis of both the government and the market, and financial concerns.…

Why do sexual violence policies still fail to systematically address men and masculinities, when the need for cultural change among men has been central in public debates since #MeToo?

Material circularity and energy efficiency are highly relevant and intertwined issues for the transition towards a carbon-neutral and circular built environment. In the Netherlands, the building sector has been rendered a priority towards a circular and low-carbon society.

Promotor: Prof.dr. M. Ubbink

Dit project onderzoekt de professionalisering van universiteitsbibliotheken in de negentiende en vroege twintigste eeuw, door de lens van het middeleeuwse handschriftenbezit. Met de Leidse Universiteitsbibliotheek als uitgangspunt werpt het licht op de veranderende praktijken rond het conserveren, behandelen…

Het Leiden University Centre for Digital Humanities (LUCDH) heeft per 1 februari een nieuwe directeur. Universitair hoofddocent Angus Mol wil in zijn nieuwe rol mensen en kennis verbinden.

Traditional hypothesis testing requires researchers to set a fixed sample size in advance. After collecting data, the test determines whether to reject the null hypothesis.

In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.

Promotor: Prof.dr. M. Ubbink, Co-promotor: G. Siegal

In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.

In this thesis,

Promotor: P.D. Grünwald

In meta-analysis, heterogeneity often exists between studies. In such cases, it is essential to investigate the sources of heterogeneity and understand the relationship between effect size and study characteristics (i.e., moderators).

Image segmentation is a fundamental task in computer vision, with applications ranging from medical diagnostics to archaeological research.

Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…

This thesis studies the geometry of representation varieties and character stacks. These are spaces parametrizing the representations of a finitely generated group, typically the fundamental group of a compact manifold, into an algebraic group G.

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.

In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.

Building a Deep Cross-media Transfer Network to extract visual relations that relieve the problem of insufficient training data for visual tasks.

Predictive maintenance (PdM) is a maintenance policy that uses the past, current, and prognosticated health condition of an asset to predict when timely maintenance should occur.

Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma

Promotor: R. Verpoorte, Co-promotores: Y.H.Choi, N.R. Mustafa

Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros

In some condensed matter systems, such as the surface of a 3D topological insulator, the electrons are effectively massless and we must necessarily use the massless Dirac equation to describe them.

In my research, we developed a method to distinguish knots. A knot is a mathematical depiction of the everyday knot that occurs in ropes and cords.

Promotor: Thomas Hankemeier, Co-promotores: Heiko van der Linden, Paul Vulto

In the first part of this thesis we study the geometry of folding patterns.

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